Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.

Abstract: A system and method for promoting and safeguarding the wellbeing of patients in relation to a fluid injection may obtain patient data; determine, based on the patient data, an initial risk prediction for a patient for a fluid injection to be administered to the patient, the initial risk prediction including a probability that the patient experiences at least one adverse event in response to the fluid injection; provide, to a user device, before the fluid injection is administered to the patient, the initial risk prediction; determine, after the fluid injection is started, sensor data associated with the patient; determine, based on the sensor data determined after the fluid injection is started, a current risk prediction including a probability that the patient experiences the at least one adverse event in response to the fluid injection; and provide, to the user device, the current risk prediction.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: A circuit connector for a humidification system, the system comprising a base unit configured to be engaged by a humidification chamber. The circuit connector comprises an inlet to fluidly connect to an outlet of the humidification chamber to receive humidified gases therefrom, an outlet to sealably connect to or integral with a conduit for directing the humidified gases to a user, and an electrical terminal for electrically coupling the circuit connector to an electrical terminal associated with the base unit. The circuit connector may be releasably and lockably connectable to the outlet of the humidification chamber and/or orientation features may control orientation of component parts of the system as they are assembled.

Abstract: Aspects of the subject technology relate to systems, methods, and computer-readable media for maintaining a heating, ventilation, and air conditioning (HVAC) system in a vehicle. Factors associated with operation of an HVAC system in a vehicle are monitored. Input data generated by monitoring the factors are applied to a machine learning model. The machine learning model is configured to predict a health of the HVAC system in relation to the operation of the HVAC system in the vehicle. An output of the machine learning model that is indicative of the health of the HVAC system is accessed. Information associated with a likelihood that the HVAC system will fail in relation to a specific time is identified based on the output of the machine learning model.

Abstract: A heat exchanger for a motor vehicle that includes at least two flat tubes and at least two corrugated fins. The flat tubes and the corrugated fins are stacked alternately one above the other in a height direction (HR) to form a stack. The flat tubes and the corrugated fins are displaced in the stack in such a way that a central height axis (HMA) of the stack is aligned at an inclination angle (NVV) to the height direction (HR).

Abstract: The present disclosure provides herbicide composition for control of annual and perennial grasses and broadleaf weeds. In one example, a non-selective herbicide composition comprises: a post-emergent herbicidal active agent; and a burndown agent. In another example, a non-selective herbicide composition comprises: a post-emergent herbicidal active agent; a residual control active agent, and a burndown agent.

Abstract: A heat exchanger for a motor vehicle that includes at least two flat tubes and at least two corrugated fins. The flat tubes and the corrugated fins are stacked alternately one above the other in a height direction (HR) to form a stack. The flat tubes and the corrugated fins are displaced in the stack in such a way that a central height axis (HMA) of the stack is aligned at an inclination angle (NW) to the height direction (HR).

Abstract: An inclined heat exchanger for use in a motor vehicle. The heat exchanger contains at least two flat tubes and at least two corrugated fins. The flat tubes and the corrugated fins are stacked alternately one above the other in a height direction (HR) to form a stack. The corrugated fins include a rhombic cross-section. A corrugated fin is also provided for use in the heat exchanger, as well as a method for manufacturing the corrugated fin.

Abstract: The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.

Abstract: A columnic actuated spring loader can be incorporated into existing structures. The system includes: a base that is positioned on a floor, a vertical column having a proximal end that is secured to the base and a distal end, dual vertical rods having proximal ends that are secured to the base and distal ends, and upper and lower spring mechanisms. The distal ends of the column and rods support an upper bearing plate. Each spring mechanism includes a support member that is slidably secured to the dual vertical rods, dual springs that are slidably attached to the dual rods, and bracing which is a network of rigid members that interconnect the support member, column and dual rods. Loads are transferred from the upper bearing plate and support plates to the base. The energy is dissipated into the foundation. The bracings distribute energy between the dual rods and the column.

Abstract: A columnic actuated spring loader can be incorporated into existing structures. The system includes: a base that is positioned on a floor, a vertical column having a proximal end that is secured to the base and a distal end, dual vertical rods having proximal ends that are secured to the base and distal ends, and upper and lower spring mechanisms. The distal ends of the column and rods support an upper bearing plate. Each spring mechanism includes a support member that is slidably secured to the dual vertical rods, dual springs that are slidably attached to the dual rods, and bracing which is a network of rigid members that interconnect the support member, column and dual rods. Loads are transferred from the upper bearing plate and support plates to the base. The energy is dissipated into the foundation. The bracings distribute energy between the dual rods and the column.

Abstract: The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.

Abstract: A fluid friction clutch includes a drivable housing having a working chamber and a reservoir, at least one opening between the reservoir and the working chamber configured to provide fluid communication between the reservoir and the working chamber, a driven disk supported for rotation in the working chamber, and a rotor mounted in the reservoir and rotatably coupled to the driven disk for rotation about an axis of rotation, the rotor having a plurality of arms, separated by a plurality of gaps, projecting away from its axis of rotation.

Abstract: A fluid friction clutch includes a drivable housing having a working chamber and a reservoir, at least one opening between the reservoir and the working chamber configured to provide fluid communication between the reservoir and the working chamber, a driven disk supported for rotation in the working chamber, and a rotor mounted in the reservoir and rotatably coupled to the driven disk for rotation about an axis of rotation, the rotor having a plurality of arms, separated by a plurality of gaps, projecting away from its axis of rotation.