Abstract: A single-use cartridge, wherein the cartridge defines a plurality of blind bores, each blind bore defining one opening at least one of the plurality of blind bores containing two mutually immiscible liquids, both of which are immiscible with water, one of the two mutually immiscible liquids having a specific gravity greater than water and the other of the two mutually immiscible liquids having a specific gravity less than water.

Abstract: Aspects of the present disclosure provide a composite liquid cell handling system, composite liquid cell processing methods, and dispensing heads for use in the systems and methods.

Abstract: A system for a mooring device is herein disclosed. The mooring device comprises a disc and a collar. The disc comprises a central orifice and one or more holes. The central orifice is mountable to a boat seat post. The holes large enough to accommodate a mooring line to pass through. The collar positionable on an end of the disc. A method for mooring a boat is further disclosed. Specifically, the method comprises mounting a mooring device onto a boat seat post. The mooring device comprises a disc and a collar. The disc comprises a central orifice and one or more holes. The central orifice is mountable to the boat seat post. The holes attachable to a mooring line. Further, the method comprises fastening the collar onto the boat seat post.

Abstract: Devices, systems and methods for making and handling liquid samples are disclosed.

Abstract: Methods, devices and systems for handling sample liquids, encapsulating liquids and magnetic particles are disclosed.

Abstract: The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including: a sampling member for acquiring or dispensing a sample; and a supply of a fluid that is immiscible with the sample; in which the device is configured to provide a continuous flow of immiscible fluid enveloping the sampling member.

Abstract: Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.

Abstract: Devices, systems, and methods for charging fluids are disclosed. The charging of fluids improves the mixing of fluids in microfluidic systems. The charging is performed by producing an ion field (50) between an ionizing electrode (20) and an opposed ground electrode (30). A fluid-containing vessel (40) is positioned between the opposed electrodes and the ion field charges the fluid (41) in the vessel.

Abstract: The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including: a sampling member for acquiring or dispensing a sample; and a supply of a fluid that is immiscible with the sample; in which the device is configured to provide a continuous flow of immiscible fluid enveloping the sampling member.

Abstract: The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including: a sampling member for acquiring or dispensing a sample; and a supply of a fluid that is immiscible with the sample; in which the device is configured to provide a continuous flow of immiscible fluid enveloping the sampling member.

Abstract: The invention is directed toward a sterile bone-tendon-bone assembly with two allograft bone blocks constructed with a cancellous portion and a cortical end portion. Each bone block has an outer curved surface with two opposing longitudinal arcuate grooves cut into the exterior surface which will allow a tendon replacement member to be wrapped around the bone block. The second bone block being in reversed orientation to the first bone block.

Abstract: A surgical punch including an upper jaw and lower jaw that are coupled at their proximal ends. The jaws have cutting edges at their distal end configured to cut in a direction from the distal ends of the jaws towards the proximal ends of the jaws. The center of rotation of the cutting trajectory can be located above the initial cutting point of the lower jaw. The upper jaw can include a reversed slope leading edge. The jaws can be slidably coupled to each other. The coupling member can include a pin and slot to couple the movable jaw to an actuating rod.

Abstract: An isometer for determining isometric graft tunnel placement for lateral side surgical augmentation or reconstruction for anterolateral or posterior lateral rotary knee instability. This graft tunnel placement isometry assessment and measurement device is designed to be used with a graft and an extra-articular technique that restores rotatory, lateral, and anterior/posterior knee stability when used by itself or in combination with intra-articular ACL/PCL reconstruction. The isometer includes an elongated body with a slider rod that slides horizontally within the body and a cannulated fixed stylus attached transversely to the first end of the elongated body. Within that cannulated fixed stylus is a guide pin that slides freely but that can also be fixed using a fixed-stylus set screw.

Abstract: Systems and methods for producing minimally invasive osteotomies to correct angular deformities of bones in and about the knee are disclosed. A method includes locating a plane in which the angle exhibited by the deformity is situated. An oblique cut is then made along a surface of the bone, such that the cut is transverse to the plane in which the angle is situated. Thereafter, the bone pieces are rotated about the cut relative to one another until a desired alignment between the bone pieces is achieved. To maintain the bone pieces in alignment, a device having an elongated body for extending into a tunnel between the bone pieces is provided. The system also includes a rigid member fixedly positioned at one end of the body. The rigid member is transverse to the body to engage one bone piece. The system further includes a locking mechanism at an opposite end of the body to engage the other bone piece.

Abstract: A femoral guide for precisely positioning a guide wire on a femur bone surface. A lumen allows a guide wire extending through the lumen to contact the bone surface at a location spaced a predetermined distance from an edge of the bone surface. With the guide wire driven into the bone, a bone tunnel can be formed substantially concentrically along the guide. Methods of precisely forming bone tunnels include the steps of engaging a bone surface edge with a tongue of the femoral guide, insertion of a guide wile through a femoral guide lumen, driving the guide wire into the bone through the lumen and forming a bone tunnel along the guide wire where a bone tunnel longitudinal axis is disposed from the edge engaged by die tongue a distance substantially equal to the distance that the tongue is disposed from the longitudinal axis of the lumen.

Abstract: Systems and methods for producing minimally invasive osteotomies to correct angular deformities of bones in and about the knee are disclosed. A method includes locating a plane in which the angle exhibited by the deformity is situated. An oblique cut is then made along a surface of the bone, such that the cut is transverse to the plane in which the angle is situated. Thereafter, the bone pieces are rotated about the cut relative to one another until a desired alignment between the bone pieces is achieved. To maintain the bone pieces in alignment, a device having an elongated body for extending into a tunnel between the bone pieces is provided. The system also includes a rigid member fixedly positioned at one end of the body. The rigid member is transverse to the body to engage one bone piece. The system further includes a locking mechanism at an opposite end of the body to engage the other bone piece.

Abstract: An isometer for determining isometric graft tunnel placement for lateral side surgical augmentation or reconstruction for anterolateral rotatory knee instability. This graft tunnel placement isometry assessment and measurement device is designed to be used with a graft and an extra-articular technique that restores rotatory, lateral, and anterior knee stability when used by itself or in combination with intra-articular ACL reconstruction. The isometer includes an elongated body with a slider rod that slides horizontally within the body and a cannulated fixed stylus attached transversely to the first end of the elongated body. Within that cannulated fixed stylus is a guide pin that slides freely but that can also be fixed using a fixed-stylus set screw. Similarly, a cannulated movable stylus is attached transversely to the first end of the slider rod, and within that cannulated movable stylus is a guide pin that slides freely but that can also be fixed using a movable-stylus set screw.

Abstract: A bioabsorbable implantable device for replacing sutures in construction of a composite graft in ligament replacement surgery. In certain embodiments the device has a female component and a male component where the female component receives and secures the male component. In other embodiments the components of the device are in the shape of a rivet or a staple. The bioabsorbable implantable devices can be used for securing tendon grafts to bone blocks and for holding together the fibers of the tendon graft when the bone-tendon-bone graft is inserted into a patient during surgery. The bioabsorbable implantable device may also be part of a package for use in surgery. The package includes a sterile container for holding at least a graft that is of a predetermined length and width. The package may also include bone blocks. The package is marked as to the graft size including the width and the length of the graft. The graft and the bone blocks may be autogenous, allogenic or constructed from man-made materials.

Abstract: A femoral guide for precisely positioning a guide wire on a bone surface of the femur includes a body having a lumen for receiving a guide wire and a tongue protruding from the body for engaging an edge or reference point on the bone surface with the tongue being spaced a predetermined distance from a longitudinal axis of the lumen. The lumen includes an opening allowing a guide wire extending through the lumen to contact the bone surface at a location spaced from the edge substantially the predetermined distance with the tongue engaging the edge. A stylus on the body can be driven into the bone to secure and stabilize the femoral guide prior to driving the guide wire into the bone through the lumen. With the guide wire driven into the bone, a bone tunnel can be formed substantially concentrically or coaxially along the guide wire such that a longitudinal axis of the bone tunnel will be disposed from the edge substantially the predetermined distance.