Patents by Inventor David McKenney

David McKenney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8663654
    Abstract: The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. The invention also relates to the use of the PS/A as a vaccine for inducing active immunity to infections caused by Staphylococcus aureus, S. epidermidis, other related coagulase-negative staphylococci and organisms carrying the ica (intracellular adhesin) locus, and to the use of antibodies directed to PS/A for inducing passive immunity to the same class of infections.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: March 4, 2014
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Gerald B. Pier, Julia Wang, David McKenney
  • Publication number: 20100260801
    Abstract: The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. The invention also relates to the use of the PS/A as a vaccine for inducing active immunity to infections caused by Staphylococcus aureus, S. epidermidis, other related coagulase-negative staphylococci and organisms carrying the ica (intracellular adhesin) locus, and to the use of antibodies directed to PS/A for inducing passive immunity to the same class of infections.
    Type: Application
    Filed: December 22, 2006
    Publication date: October 14, 2010
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventors: Gerald B. Pier, Julia Y. Wang, David McKenney
  • Patent number: 7252828
    Abstract: The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. The invention also relates to the use of the PS/A as a vaccine for inducing active immunity to infections caused by Staphylococcus aureus, S. epidermidis, other related coagulase-negative staphylococci and organisms carrying the ica (intracellular adhesin) locus, and to the use of antibodies directed to PS/A for inducing passive immunity to the same class of infections.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: August 7, 2007
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Gerald B. Pier, Julia Y. Wang, David McKenney
  • Publication number: 20060207687
    Abstract: Systems for orienting strands and/or other types of particles are provided. The systems may have tabs which extend from orienting disks and/or collars and/or spacers which may be disposed on shafts. The tabs may prevent accumulation of strands between disks utilized within an orienting system. For example, the tabs may contact strands and/or other particles and guide or force the particles to be moved past the disks toward successive disks, or onto a screen or conveyor line.
    Type: Application
    Filed: March 15, 2005
    Publication date: September 21, 2006
    Inventors: Mark Churchland, David McKenney, Joseph Jenkins, Dylan Gates, Paul Chambers
  • Publication number: 20020119166
    Abstract: The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. The invention also relates to the use of the PS/A as a vaccine for inducing active immunity to infections caused by Staphylococcus aureus, S. epidermidis, other related coagulase-negative staphylococci and organisms carrying the ica (intracellular adhesin) locus, and to the use of antibodies directed to PS/A for inducing passive immunity to the same class of infections.
    Type: Application
    Filed: January 26, 2001
    Publication date: August 29, 2002
    Inventors: Gerald Pier, Ying Wang, David McKenney