Abstract: A method includes receiving information indicative of a first vehicle identification number (VIN) for a first vehicle, determining that the first vehicle includes a first recalled component by comparing the first VIN to information in a recall database stored in a memory of an auditing system, receiving first image data generated by a mobile device, the first image data being reproducible as a first image of the first VIN on the first vehicle and associated with a first location of the mobile device, receiving second image data generated by the mobile device, the second image data being reproducible as a second image of at least a portion of the first recalled component and associated with a second location of the mobile device, and validating a status of the first recalled component by comparing the first location of the mobile and the second location of the mobile device.

Abstract: Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. These have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy of polynucleotide sequencing applications.

Abstract: Methods and systems are provided for small molecule analyte detection using digital signals, key encryption, and communications protocols. The methods provide detection of a large numbers of proteins, peptides, RNA molecules, and DNA molecules in a single optical or electrical detection assay within a large dynamic range.

Abstract: Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. These have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy of polynucleotide sequencing applications.

Abstract: Methods are provided for detecting a single compound analyte immobilized to a solid substrate by serially contacting and removing different probes to the same analyte.

Abstract: A method includes receiving information indicative of a first vehicle identification number (VIN) for a first vehicle, determining that the first vehicle includes a first recalled component by comparing the first VIN to information in a recall database stored in a memory of an auditing system, receiving first image data generated by a mobile device, the first image data being reproducible as a first image of the first VIN on the first vehicle and associated with a first location of the mobile device, receiving second image data generated by the mobile device, the second image data being reproducible as a second image of at least a portion of the first recalled component and associated with a second location of the mobile device, and validating a status of the first recalled component by comparing the first location of the mobile and the second location of the mobile device.

Abstract: Electrical detection methods are used to identify and further characterize single-molecule target analytes such as proteins and nucleic acids. A composition including a probe region and a tail region is contacted with a target analyte. The probe region specifically binds to the target analyte. The tail region is coupled to the probe region, and includes a nucleic acid template for polynucleotide synthesis. When conditions are such that polynucleotide synthesis occurs along the tail region, one hydrogen ion is released for every nucleotide that is incorporated into the tail region. A transistor such as an ISFET detects and measures changes in ion concentration, and these measurements can be used to identify the tail region and thus characterize the corresponding target analyte.

Abstract: Electrical detection methods are used to identify and further characterize single-molecule target analytes such as proteins and nucleic acids. A composition including a probe region and a tail region is contacted with a target analyte. The probe region specifically binds to the target analyte. The tail region is coupled to the probe region, and includes a nucleic acid template for polynucleotide synthesis. When conditions are such that polynucleotide synthesis occurs along the tail region, one hydrogen ion is released for every nucleotide that is incorporated into the tail region. A transistor such as an ISFET detects and measures changes in ion concentration, and these measurements can be used to identify the tail region and thus characterize the corresponding target analyte.

Abstract: The present invention discloses a method of determining the delivery of a dosage from an inhaler able to deliver an active pharmaceutical ingredient (API) as an inhalable aerosol to a user comprising at least the steps of (i) measuring user inhalation airflow during a use occasion of the inhaler to determine the portion of the inhalation above an airspeed threshold F1; (ii) measuring the volume of air inhaled by the user during the use occasion of the inhaler to determine the portion of inhalation occurring prior to a swept volume threshold V1; (iii) determining a first portion P1 of the dosage provided by the inhaler during the use occasion above the threshold F1 and provided prior to threshold V1.

Abstract: Methods are provided for detecting a single compound analyte immobilized to a solid substrate by serially contacting and removing different probes to the same analyte.

Abstract: Electrical detection methods are used to identify and further characterize single-molecule target analytes such as proteins and nucleic acids. A composition including a probe region and a tail region is contacted with a target analyte. The probe region specifically binds to the target analyte. The tail region is coupled to the probe region, and includes a nucleic acid template for polynucleotide synthesis. When conditions are such that polynucleotide synthesis occurs along the tail region, one hydrogen ion is released for every nucleotide that is incorporated into the tail region. A transistor such as an ISFET detects and measures changes in ion concentration, and these measurements can be used to identify the tail region and thus characterize the corresponding target analyte.

Abstract: Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. These have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy of polynucleotide sequencing applications.

Abstract: Electrical detection methods are used to identify and further characterize single-molecule target analytes such as proteins and nucleic acids. A composition including a probe region and a tail region is contacted with a target analyte. The probe region specifically binds to the target analyte. The tail region is coupled to the probe region, and includes a nucleic acid template for polynucleotide synthesis. When conditions are such that polynucleotide synthesis occurs along the tail region, one hydrogen ion is released for every nucleotide that is incorporated into the tail region. A transistor such as an ISFET detects and measures changes in ion concentration, and these measurements can be used to identify the tail region and thus characterize the corresponding target analyte.

Abstract: Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. These have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy of polynucleotide sequencing applications.

Abstract: Methods and systems are provided for small molecule analyte detection using digital signals, key encryption, and communications protocols. The methods provide detection of a large numbers of proteins, peptides, RNA molecules, and DNA molecules in a single optical or electrical detection assay within a large dynamic range.

Abstract: Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. These have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy of polynucleotide sequencing applications.

Abstract: A non-combustible tobacco article for use in conjunction with a heat source to produce an inhalable aerosol includes at least one tobacco derived portion, at least one distal filter portion and at least one mouth-end filter portion held together in an overwrap; the complete article having a compressibility factor in the longitudinal axis of <10%.

Abstract: In one aspect, a device includes at least one processor, a display accessible to the at least one processor, and storage accessible to the at least one processor. The storage includes instructions executable by the at least one processor to present an image of an object on the display, and present a graphical user interface (GUI) on the display with the GUI indicating the object. The instructions are also executable by the processor to present, on the GUI, at least one link to content that an end-user may associate with the object or that an end-user has associated with the object.

Abstract: Creating security enclaves includes determining one or more parameters of one or more applications and one or more services operating in the network. An optimal number of clusters for grouping the one or more applications and the one or more services is determined based on the one or more parameters. Then, the one or more applications and the one or more services are grouped into the clusters and one or more security enclaves are applied to each of the clusters so as to maximize operational security of the network.

Abstract: A method, electronic device, and accessory for carrying out functions based on reflected electromagnetic radiation are provided. According to one implementation, an electronic device transmits electromagnetic radiation (“EMR”) to an accessory and detects a reflection of the transmitted EMR off of the accessory. A characteristic of the reflected EMR maps to a predetermined function associated with the accessory, which the electronic device performs.