Abstract: Apparatus and method for measuring ophthalmic formulation retention on the surface of an eye include dissolving a fluorescent macromolecule in an ophthalmic formulation to form a fluorescently labelled formulation; topically administering the fluorescently labelled formulation to an eye, said fluorescently labelled formulation forming a thin film on the eye surface. Apparatus is provided for illuminating the eye to cause fluorescence of the fluorescently labelled formulation as the fluorescently labelled formulation thin film is eliminated from the eye by normal blinking and lacrimation; and for measuring fluorescence from the thin film as a function of time.

Abstract: Apparatus and method for measuring ophthalmic formulation retention on the surface of an eye include dissolving a fluorescent macromolecule in an ophthalmic formulation to form a fluorescently labelled formulation; topically administering the fluorescently labelled formulation to an eye, said fluorescently labelled formulation forming a thin film on the eye surface. Apparatus is provided for illuminating the eye to cause fluorescence of the fluorescently labelled formulation as the fluorescently labelled formulation thin film is eliminated from the eye by normal blinking and lacrimation; and for measuring fluorescence from the thin film as a function of time.

Abstract: A system for providing controlled release of an active agent in an eye includes a device with a shape thereof for enabling placement of the device under a conjunctiva of an eye and additionally preventing migration of the device in the eye after placement of the device under the conjunctiva. The device may be formed of a material permeable to the passage of an agent disposed in said device. In addition, a tracer may be incorporated in the device to enable visual indication of the amount of active agent in said device when said device is disposed under the conjunctiva. To selectively treat specific areas of the eye, an impermeable layer may be provided for preventing diffusion of the active agent from a selected area of the device.

Abstract: A method for treating hydrophilic and rigid gas permeable contact lenses, as well as the manufacture of protein adhesion resistant and gas permeable enhanced lenses, is obtained through purging the hydrated contact lens, formed from polymer comprising hydrogen atoms, substantially all water and oxygen, and thereafter exposing the purged contact lens to a fluorine-containing gas in non-plasma conditions for a period of time and at a temperature sufficient to replace hydrogen atoms in the polymer in order to inhibit protein deposits on the contact lens. The conditions of fluorine exposure can be controlled in order to provide a gas permeable enhanced contact lens.

Abstract: The invention is a method for accumulating and displaying digital waveform data, representing the behavior over time of an electrical signal that includes the steps of: repeatedly acquiring and digitizing (10) waveform data during a first set of time intervals, repeatedly acquiring and digitizing (10) waveform data during a second set of time intervals, the second set of time intervals alternating with the first set of time intervals, during each one of the time intervals in the first set of time intervals, ORing (83) each acquired and digitized waveform together to produce first composite waveforms, during each one of the time intervals in the second set of time intervals, ORing (86) each acquired and digitized waveform together to produce second composite waveforms, displaying (81,84) each first composite waveform during a next occurring time interval in the second set of time intervals, and displaying (81,84) each second composite waveform during a next occurring time interval in the first set of time inte

Abstract: Apparatus and method for measuring ophthalmic formulation retention on the surface of an eye include dissolving a fluorescent macromolecule in an ophthalmic formulation to form a fluorescently labelled formulation; topically administering the fluorescently labelled formulation to an eye, said fluorescently labelled formulation forming a thin film on the eye surface. Apparatus is provided for illuminating the eye to cause fluorescence of the fluorescently labelled formulation as the fluorescently labelled formulation thin film is eliminated from the eye by normal blinking and lacrimation; and for measuring fluorescence from the thin film as a function of time.

Abstract: A method for treating hydrophilic and rigid gas permeable contact lenses, as well as the manufacture of protein adhesion resistant and gas permeable enhanced lenses, is obtained through purging the hydrated contact lens, formed from polymer comprising hydrogen atoms, substantially all water and oxygen, and thereafter exposing the purged contact lens to a fluorine-containing gas in non-plasma conditions for a period of time and at a temperature sufficient to replace hydrogen atoms in the polymer in order to inhibit protein deposits on the contact lens. The conditions of fluorine exposure can be controlled in order to provide a gas permeable enhanced contact lens.

Abstract: A system for providing controlled release of an active agent in an eye includes a device with a shape thereof for enabling placement of the device under a conjunctiva of an eye and additionally preventing migration of the device in the eye after placement of the device under the conjunctiva. The device may be formed of a material permeable to the passage of an agent disposed in said device. In addition, a tracer may be incorporated in the device to enable visual indication of the amount of active agent in said device when said device is disposed under the conjunctiva. To selectively treat specific areas of the eye, an impermeable layer may be provided for preventing diffusion of the active agent from a selected area of the device.

Abstract: A system for providing controlled release of an active agent in an eye includes a device with a shape thereof for enabling placement of the device under a conjunctiva of an eye and additionally preventing migration of the device in the eye after placement of the device under the conjunctiva. The device may be formed of a material permeable to the passage of an agent disposed in said device. In addition, a tracer may be incorporated in the device to enable visual indication of the amount of active agent in said device when said device is disposed under the conjunctiva. To selectively treat specific areas of the eye, an impermeable layer may be provided for preventing diffusion of the active agent from a selected area of the device.

Abstract: A detection circuit (30, 32) for carrying out a rapid search technique for locating the position of a stylus (12) relative to a display screen (10). A microprocessor (34) and related components select a group of light detectors (20, 28) that are positioned near the display screen (10). The summed output current of the selected group of detectors (20, 28) is monitored to determine whether the output of any detector in the selected group is reduced because of the presence of a stylus (12). Whenever the selected group shows such reduction in output current, that selected groups is divided into two subgroups. The subgroup having reduced current output due to the presence of the stylus (12) is further divided until the particular detector(s) having reduced output current is found, the position of the detector is correlated to the location of the stylus (12) relative to the screen (10).

Abstract: A flow selector device whose fluid flow is regulated by the rotational setting of a rotor body in a housing; and although the metering passageways have outlets spaced from the axis of the rotor and its manipulating shank, other passageways are provided in the housing, which channel the fluid then to an outlet in and concentric with the rotor and its flow-rate adjustment shank. One of those other passageways is an annular groove formed into the rotor's manipulating shank, leading to a radial passageway in the shank, thus carrying fluid to the shank outlet channel regardless of the rotational setting of the rotor. Another of those other passageways is in the housing; and its provision is facilitated by forming it to open onto an outer face-portion of the housing, then sealing the outer portion of the passageways by a ball member forced into the outer end of the passageway. The rotor is held axially of the rotor by a snap ring, and by a nylon ring between the snap ring and the housing.

Abstract: A capacitive touch panel system (10) having a faceplate (14) with an electrically conductive layer (20) of a consistent resistivity employs a position measurement apparatus (12) to generate an address signal indicative of a position (46) on the faceplate in contact with a stylus (48). The position measurement apparatus includes a position measurement signal source (56) that generates a square-wave measurement signal of a frequency that varies in a substantially random manner. The position measurement signal is applied to a first pair of opposed electrodes (36) and (40) and a second pair of opposed electrodes (38) and (42) positioned along respective side margins (26, 30, 28, and 32) of the faceplate. The resistivity of the conductive layer establishes effective resistances of R.sub.x and R.sub.y between the respective first and second pairs of electrodes.