Patents by Inventor David Melanson

David Melanson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240148385
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.
    Type: Application
    Filed: October 13, 2023
    Publication date: May 9, 2024
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Publication number: 20240074766
    Abstract: Devices and methods for occluding the left atrial appendage (LAA) to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. A foam implant encapsulated with a tough thromboresistent membrane is placed via transvascular means into the LAA and anchored with adhesives and/or mechanical anchors. Tissue over- and in-growth are optimized to anchor the implant in place and provide a permanent occlusion.
    Type: Application
    Filed: August 7, 2023
    Publication date: March 7, 2024
    Inventors: Aaron V. Kaplan, David Melanson, Carol Devellian, Andy H. Levine
  • Patent number: 11786256
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: October 17, 2023
    Assignee: CONFORMAL MEDICAL, INC.
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Patent number: 11717303
    Abstract: Devices and methods for occluding the left atrial appendage (LAA) to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. A foam implant encapsulated with a tough thromboresistent membrane is placed via transvascular means into the LAA and anchored with adhesives and/or mechanical anchors. Tissue over- and in-growth are optimized to anchor the implant in place and provide a permanent occlusion.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: August 8, 2023
    Assignee: CONFORMAL MEDICAL, INC.
    Inventors: Aaron V. Kaplan, David Melanson, Carol Devellian, Andy H. Levine
  • Publication number: 20230071677
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. The device may have a thromboresistant cover at a proximal end. The frame may have recapture struts inclining radially outwardly from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame and into the foam to engage tissue.
    Type: Application
    Filed: August 26, 2022
    Publication date: March 9, 2023
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Publication number: 20230032647
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA) to exclude the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. An implant is delivered via transcatheter delivery into the LAA. The implant includes a conformable structure comprising a foam body and internal support. The support includes anchors that penetrate the foam body and anchor the implant to the walls of the LAA. The implant provides compliance such that it conforms to the native configuration of the LAA.
    Type: Application
    Filed: July 29, 2022
    Publication date: February 2, 2023
    Inventors: Aaron V. Kaplan, David Melanson, Carol Devellian, Andy H. Levine, Andres Chamorro
  • Patent number: 11426172
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. The device may have a thromboresistant cover at a proximal end. The frame may have recapture struts inclining radially outwardly from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame and into the foam to engage tissue.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: August 30, 2022
    Assignee: Conformal Medical, Inc.
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Publication number: 20220265280
    Abstract: Devices and methods for occluding the left atrial appendage (LAA) with a device having multifunctional capability. The device is delivered via transcatheter delivery into the LAA and anchored using a compliant frame and scaffold, which may be foam. The device further includes one or more electronic systems to provide a multitude of features related to sensing, electrical stimulation, pacing, communication, etc. The device may have an open configuration where an opening in the proximal end of the device allows for delivery of one or more sensors into and/or through the device. The device may be manipulated into a closed configuration to secure the electronic systems therein and close off the proximal end to provide the occlusive effects. The electronic systems therein may then be used for the various electronic and other functions.
    Type: Application
    Filed: February 18, 2022
    Publication date: August 25, 2022
    Inventors: Andres Chamorro, David A. Melanson, Andy H. Levine, Carol Devellian, Aaron V. Kaplan, Jacob Carl Hahn
  • Patent number: 11399842
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA) to exclude the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. An implant is delivered via transcatheter delivery into the LAA. The implant includes a conformable structure comprising a foam body and internal support. The support includes anchors that penetrate the foam body and anchor the implant to the walls of the LAA. The implant provides compliance such that it conforms to the native configuration of the LAA.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: August 2, 2022
    Assignee: Conformal Medical, Inc.
    Inventors: Aaron V. Kaplan, David Melanson, Carol Devellian, Andy H. Levine, Andres Chamorro
  • Publication number: 20220192676
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA) to exclude the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. An implant is delivered via transcatheter delivery into the LAA. The implant includes a conformable structure comprising a foam body and internal support. The support includes anchors that penetrate the foam body and anchor the implant to the walls of the LAA. The implant provides compliance such that it conforms to the native configuration of the LAA.
    Type: Application
    Filed: April 10, 2020
    Publication date: June 23, 2022
    Inventors: Aaron V. Kaplan, David Melanson, Carol Devellian, Andy H. Levine, Andres Chamorro
  • Publication number: 20210393271
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.
    Type: Application
    Filed: June 3, 2021
    Publication date: December 23, 2021
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Patent number: 11116510
    Abstract: Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: September 14, 2021
    Assignee: Conformal Medical, Inc.
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Publication number: 20210169500
    Abstract: Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame having anchors and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. A loader includes a conical portion with guides and a reservoir for submerging the foam implant prior to loading and delivery.
    Type: Application
    Filed: February 23, 2021
    Publication date: June 10, 2021
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Patent number: 11026695
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: June 8, 2021
    Assignee: CONFORMAL MEDICAL, INC.
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Patent number: 11000396
    Abstract: A gastrointestinal implant device (2800) comprises a planar proximal element (220) configured to reside in a stomach to resist distal migration, a distal element (222) configured to reside in an intestine to resist proximal migration and one or more tethers (224) coupling the planar proximal element to the distal element.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: May 11, 2021
    Assignee: GI Dynamics, Inc.
    Inventors: Andres Chamorro, III, Andy H. Levine, David A. Melanson, Barry Maxwell, Richard A. Gambale
  • Publication number: 20200305889
    Abstract: Devices and methods are described for occluding the left atrial appendage (LAA) to exclude the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. An implant is delivered via transcatheter delivery into the LAA. The implant includes a conformable structure comprising a foam body and internal support. The support includes anchors that penetrate the foam body and anchor the implant to the walls of the LAA. The implant provides compliance such that it conforms to the native configuration of the LAA.
    Type: Application
    Filed: April 10, 2020
    Publication date: October 1, 2020
    Inventors: Aaron V. Kaplan, David Melanson, Carol Devellian, Andy H. Levine, Andres Chamorro
  • Publication number: 20200253615
    Abstract: Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.
    Type: Application
    Filed: February 18, 2020
    Publication date: August 13, 2020
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Publication number: 20200253614
    Abstract: Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.
    Type: Application
    Filed: February 5, 2020
    Publication date: August 13, 2020
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Publication number: 20200253611
    Abstract: Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.
    Type: Application
    Filed: February 18, 2020
    Publication date: August 13, 2020
    Applicant: Conformal Medical, Inc.
    Inventors: David A. Melanson, Andy H. Levine, James H. Loper, Michael T. Radford, Carol Devellian, Aaron V. Kaplan, Ronald B. Lamport
  • Publication number: 20200237193
    Abstract: An endoscope hood device for moving a gastrointestinal implant device within a natural lumen of a gastrointestinal tract. The endoscope hood device comprises an atraumatic flared retrieval hood configured to attach to and fit over a distal end of an endoscope. The atraumatic flared retrieval hood comprises a length configured to cover a plurality of protrusions on a surface of the gastrointestinal implant device, the plurality of protrusions comprising both proximal facing protrusions and distal facing protrusions of the gastrointestinal implant device. The atraumatic flared retrieval hood comprises a diameter configured to fit within a human esophagus without damage to the esophagus, and comprises a material of a bend radius configured to move slidably against the esophagus without damage to the esophagus.
    Type: Application
    Filed: January 31, 2020
    Publication date: July 30, 2020
    Inventors: Andres CHAMORRO, III, David A. MELANSON, Barry MAXWELL, Ian K. PARKER