Patents by Inventor David Mendelowitz

David Mendelowitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTRANASAL LEPTIN COMPOSITIONS AND METHODS OF USE THEREOF FOR PREVENTION OF OPIOID INDUCED RESPIRATORY DEPRESSION IN OBESITY
    Publication number: 20220273768
    Abstract: The present disclosure generally relates to compositions and methods of treating opioid-induced respiratory depression in a subject in need thereof, the method comprising administering leptin.
    Type: Application
    Filed: May 18, 2022
    Publication date: September 1, 2022
    Inventors: David MENDELOWITZ, Vsevolod POLOTSKY, Carla FREIRE
  • COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE
    Publication number: 20220008500
    Abstract: Methods of treating a subject having heart failure including heart failure with reduced ejection fraction, heart failure with preserved ejection fraction, and left ventricular hypertrophy-induced heart failure. The methods include activating hypothalamic oxytocin neurons in the brain of the subject and/or administering intranasally to the subject a therapeutically effective amount of oxytocin. Intranasal formulations for the treatment of a subject diagnosed with heart failure are also provided.
    Type: Application
    Filed: June 16, 2021
    Publication date: January 13, 2022
    Inventors: Matthew Kay, Kara Garrott, Jhansi Dyavanapalli, David Mendelowitz, Gregory Trachiotis
  • OXYTOCIN IMPROVES TREATMENT OF OBSTRUCTIVE SLEEP APNEA
    Publication number: 20210322510
    Abstract: The present disclosure provides methods for treating obstructive sleep apnea (OSA) and OSA induced cardiorespiratory diseases. The disclosure provides, inter alia, methods for treating or alleviating: OSA or OSA induced hypertension, cardiac arrhythmias, myocardial ischemia, sudden cardiac death or stroke, by administering oxytocin. The disclosure further provides methods for improving sleep satisfaction in OSA patients by administering oxytocin.
    Type: Application
    Filed: November 18, 2020
    Publication date: October 21, 2021
    Inventors: David MENDELOWITZ, Vivek JAIN, Heather JAMESON, Jay Shawn KIMBRO
  • Oxytocin improves treatment of obstructive sleep apnea
    Patent number: 10842845
    Abstract: The present disclosure provides methods for treating obstructive sleep apnea (OSA) and OSA induced cardiorespiratory diseases. The disclosure provides, inter alia, methods for treating or alleviating: OSA or OSA induced hypertension, cardiac arrhythmias, myocardial ischemia, sudden cardiac death or stroke, by administering oxytocin. The disclosure further provides methods for improving sleep satisfaction in OSA patients by administering oxytocin.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: November 24, 2020
    Assignee: THE GEORGE WASHINGTON UNIVERSITY
    Inventors: David Mendelowitz, Vivek Jain, Heather Jameson, Jay Shawn Kimbro
  • COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE
    Publication number: 20200061149
    Abstract: Methods of treating a subject having heart failure including heart failure with reduced ejection fraction, heart failure with preserved ejection fraction, and left ventricular hypertrophy-induced heart failure. The methods include activating hypothalamic oxytocin neurons in the brain of the subject and/or administering intranasally to the subject a therapeutically effective amount of oxytocin. Intranasal formulations for the treatment of a subject diagnosed with heart failure are also provided.
    Type: Application
    Filed: September 6, 2019
    Publication date: February 27, 2020
    Inventors: Matthew Kay, Kara Garrott, Jhansi Dyavanapalli, David Mendelowitz, Trachiotis Gregory
  • OXYTOCIN IMPROVES TREATMENT OF OBSTRUCTIVE SLEEP APNEA
    Publication number: 20190076501
    Abstract: The present disclosure provides methods for treating obstructive sleep apnea (OSA) and OSA induced cardiorespiratory diseases. The disclosure provides, inter alia, methods for treating or alleviating: OSA or OSA induced hypertension, cardiac arrhythmias, myocardial ischemia, sudden cardiac death or stroke, by administering oxytocin. The disclosure further provides methods for improving sleep satisfaction in OSA patients by administering oxytocin.
    Type: Application
    Filed: November 8, 2018
    Publication date: March 14, 2019
    Inventors: David MENDELOWITZ, Vivek JAIN, Heather JAMESON, Jay Shawn KIMBRO
  • Oxytocin improves treatment of obstructive sleep apnea
    Patent number: 10166268
    Abstract: The present disclosure provides methods for treating obstructive sleep apnea (OSA) and OSA induced cardiorespiratory diseases. The disclosure provides, inter alia, methods for treating or alleviating: OSA or OSA induced hypertension, cardiac arrhythmias, myocardial ischemia, sudden cardiac death or stroke, by administering oxytocin. The disclosure further provides methods for improving sleep satisfaction in OSA patients by administering oxytocin.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: January 1, 2019
    Assignee: THE GEORGE WASHINGTON UNIVERSITY
    Inventors: David Mendelowitz, Vivek Jain, Heather Jameson, Jay Shawn Kimbro
  • OXYTOCIN IMPROVES TREATMENT OF OBSTRUCTIVE SLEEP APNEA
    Publication number: 20170143790
    Abstract: The present disclosure provides methods for treating obstructive sleep apnea (OSA) and OSA induced cardiorespiratory diseases. The disclosure provides, inter alia, methods for treating or alleviating: OSA or OSA induced hypertension, cardiac arrhythmias, myocardial ischemia, sudden cardiac death or stroke, by administering oxytocin. The disclosure further provides methods for improving sleep satisfaction in OSA patients by administering oxytocin.
    Type: Application
    Filed: July 2, 2015
    Publication date: May 25, 2017
    Inventors: David Mendelowitz, Vivek Jain, Heather Jameson, Jay Shawn Kimbro