Patents by Inventor David Michael Evans

David Michael Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240169300
    Abstract: The present invention relates to systems and methods for hypothetical testing of a supply chain optimization. The computerized method for hypothetical optimization of a supply chain receives a hypothetical optimization query, generates variable definitions responsive to the query, generates scope definitions responsive to the query, generates presentation definitions and generates an optimization parameter set using the variable definitions and the scope definitions. The parameter set is used to optimize a hypothetical supply chain via an artificial intelligence (AI) modeling platform. One or more recommendations are generated based upon the optimized hypothetical supply chain.
    Type: Application
    Filed: November 17, 2023
    Publication date: May 23, 2024
    Inventors: David Michael Evans, Robert Derward Rogers, Vishnuvyas Sethumadhavan
  • Publication number: 20240112110
    Abstract: The present invention relates to systems and methods for ingesting of raw client data into a supply chain optimization system. The client enterprise data system (EDS) provides raw data, typically in tabular format across many files, to a data management module of the optimization system. This data is then profiled. and a set of mapping AI models is applied to the profiled data. Each of the plurality of mapping AI models corresponds to a single input feature of the optimization model. As the mapping models are applied, a live preview is generated. This live preview is reviewable by a human operator, and human input can be provided. When there is input, the individual mapping model is updated (without impacting the other mapping models), and a new live preview for that given feature is generated. The resulting standardized feature set may be consumed by the supply chain optimization model.
    Type: Application
    Filed: September 20, 2023
    Publication date: April 4, 2024
    Inventors: David Michael Evans, Robert Derward Rogers, Vishnuvyas Sethumadhavan, Mehran Najafi
  • Publication number: 20240059691
    Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in medicine; and methods of treating patients with such compounds; wherein A, W, R5, n, Z, X, Y and B are as defined herein. The present invention also relates to compounds useful as synthetic intermediates of compounds of formula (I).
    Type: Application
    Filed: December 1, 2021
    Publication date: February 22, 2024
    Inventors: Mitchell Lewis CHILDS, Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, William Jack GREVES, Simon Teanby HODGSON, Alessandro MAZZACANI, Carl Leslie NORTH, Alicja Stela OBARA, Michael Bryan ROE, David Philip ROOKER, Michael John STOCKS, Louise Michelle BIRCH, Mark PICHOWICZ, Rachael PITTAWAY, Alun John SMITH, Adam Eric THROUP, Joseph William WRIGGLESWORTH, Xuezheng YANG, David Edward CLARK
  • Patent number: 11897102
    Abstract: A hydraulic screw tensioning device includes a tubular body, with a through opening and an annular cylinder chamber surrounding the through opening and a tubular piston movably supported in the tubular body and connectable to a screw to be tensioned. The tubular piston includes a stepped outer portion and divides the annular cylinder chamber into a first pressure chamber and a second pressure chamber. The second pressure chamber is closed by an annular end cap secured to the tubular body. The first pressure chamber is connectable to a pressure source for hydraulic fluid. The second pressure chamber is connectable to a pressure source for a compressible medium via a conduit connector mounted on the annular end cap. The conduit connector extends radially in relation to a geometric axis (A-A) of the tubular body. A damage protecting structure is provided to protect the conduit connector against accidental physical damage.
    Type: Grant
    Filed: September 1, 2022
    Date of Patent: February 13, 2024
    Assignee: ATLAS COPCO INDUSTRIAL TECHNIQUE AB
    Inventors: David Michael Evans, Adam Thomas Lee
  • Publication number: 20230306347
    Abstract: The present invention relates to systems and methods for intelligently optimizing supply chain is provided. In particular, the systems and methods provide the capability to configure supply chain systems so as to: balance between cost and service is optimized and profitability maximized; configure system parameters to respond to both current and future risks; ensure that variability is built into plans enabling maximized efficiency; and human error and bias are eliminated from the planning process such that pro-active rather than reactive behavior becomes the norm.
    Type: Application
    Filed: March 23, 2023
    Publication date: September 28, 2023
    Inventors: David Michael Evans, Robert Derward Rogers, Vishnuvyas Sethumadhavan
  • Publication number: 20230250080
    Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.
    Type: Application
    Filed: March 27, 2023
    Publication date: August 10, 2023
    Inventors: Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, Simon Teanby HODGSON, Alessandro MAZZACANI, Michael John STOCKS, Thomas Matthew BAKER, Matthew Robert CONROY, Alun John SMITH, David Edward CLARK
  • Patent number: 11613527
    Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.
    Type: Grant
    Filed: October 8, 2021
    Date of Patent: March 28, 2023
    Assignee: KalVista Pharmaceuticals Limited
    Inventors: Rebecca Louise Davie, Hannah Joy Edwards, David Michael Evans, Simon Teanby Hodgson, Alessandro Mazzacani, Michael John Stocks, Thomas Matthew Baker, Matthew Robert Conroy, Alun John Smith, David Edward Clark
  • Publication number: 20220410356
    Abstract: A hydraulic screw tensioning device includes a tubular body, with a through opening and an annular cylinder chamber surrounding the through opening and a tubular piston movably supported in the tubular body and connectable to a screw to be tensioned. The tubular piston includes a stepped outer portion and divides the annular cylinder chamber into a first pressure chamber and a second pressure chamber. The second pressure chamber is closed by an annular end cap secured to the tubular body. The first pressure chamber is connectable to a pressure source for hydraulic fluid. The second pressure chamber is connectable to a pressure source for a compressible medium via a conduit connector mounted on the annular end cap. The conduit connector extends radially in relation to a geometric axis (A-A) of the tubular body. A damage protecting structure is provided to protect the conduit connector against accidental physical damage.
    Type: Application
    Filed: September 1, 2022
    Publication date: December 29, 2022
    Applicant: ATLAS COPCO INDUSTRIAL TECHNIQUE AB
    Inventors: David Michael EVANS, Adam Thomas LEE
  • Publication number: 20220363668
    Abstract: The present invention provides compounds of formula (I) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined herein.
    Type: Application
    Filed: February 13, 2020
    Publication date: November 17, 2022
    Inventors: Hannah Joy EDWARDS, David Michael EVANS, Alessandro MAZZACANI, Alicja Stela OBARA, David Edward CLARK, Emanuela GANCIA, Rachael PITTAWAY, Joseph William WRIGGLESWORTH
  • Publication number: 20220309436
    Abstract: The present invention relates to systems and methods for intelligently optimizing supply chain is provided. In particular, the systems and methods provide the capability to configure supply chain systems so as to: balance between cost and service is optimised and profitability maximised; configure system parameters to respond to both current and future risks; ensure that variability is built into plans enabling maximised efficiency; and human error and bias are eliminated from the planning process such that pro-active rather than reactive behaviour becomes the norm.
    Type: Application
    Filed: April 12, 2022
    Publication date: September 29, 2022
    Inventors: David Michael Evans, Robert Derward Rogers
  • Publication number: 20220298138
    Abstract: The present invention provides compounds of formula (I): Formula (I) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein A, Y, n, R1, R2A, R2B, R3 and *1 are as defined herein.
    Type: Application
    Filed: August 21, 2019
    Publication date: September 22, 2022
    Inventors: Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, Simon Teanby HODGSON, Sally Louise MARSH, Alessandro MAZZACANI, David Philip ROOKER, Michael John STOCKS, Andrew Peter CRIDLAND, Emanuela GANCIA, Julie Nicole HAMBLIN, Paul Stuart HINCHLIFFE, Stefano LEVANTO, Terence Aaron PANCHAL, Iain Robert MILLER
  • Publication number: 20220298141
    Abstract: The present invention provides compounds of formula (I) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein A, B, and, n, are as defined herein.
    Type: Application
    Filed: August 21, 2019
    Publication date: September 22, 2022
    Inventors: Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, Simon Teanby HODGSON, Andrew Peter CRIDLAND, Emanuela GANCIA, Erica Lee GOLDSMITH, Paul Stuart HINCHLIFFE, Karamjit Singh JANDU, Alun John SMITH
  • Publication number: 20220289727
    Abstract: The present invention provides compounds of formula (I) or (Ia) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein A, B, n, R2, R3, R4, R5, and R6 are as defined herein.
    Type: Application
    Filed: February 13, 2020
    Publication date: September 15, 2022
    Inventors: Mitchell Lewis CHILDS, Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, Simon Teanby HODGSON, Alessandro MAZZACANI, David Edward CLARK, Paul Stuart HINCHLIFFE, Thomas Matthew BAKER, Colin Peter SAMBROOK SMITH, Alun John SMITH, Joseph William WRIGGLESWORTH, Xuezheng YANG
  • Publication number: 20220289729
    Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.
    Type: Application
    Filed: October 20, 2021
    Publication date: September 15, 2022
    Inventors: Rebecca Louise Davie, Hannah Joy Edwards, David Michael Evans, Simon Teanby Hodgson
  • Publication number: 20220153724
    Abstract: The present invention provides compounds of formula (I), compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, R12, R13, A, L, B, n, W, X, Y and Z are as defined herein.
    Type: Application
    Filed: February 7, 2022
    Publication date: May 19, 2022
    Inventors: Hannah Joy Edwards, David Michael Evans, Premji Meghani, Andrew Richard Novak
  • Publication number: 20220048894
    Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.
    Type: Application
    Filed: October 8, 2021
    Publication date: February 17, 2022
    Inventors: Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, Simon Teanby HODGSON, Alessandro MAZZACANI, Michael John STOCKS, Thomas Matthew BAKER, Matthew Robert CONROY, Alun John SMITH, David Edward CLARK
  • Patent number: 11242333
    Abstract: The present invention provides compounds of formula (I), compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, R12, R13, A, L, B, n, W, X, Y and Z are as defined herein.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: February 8, 2022
    Assignee: Kalvista Pharmaceuticals Limited
    Inventors: Hannah Joy Edwards, David Michael Evans, Premji Meghani, Andrew Richard Novak
  • Publication number: 20220002275
    Abstract: The present invention provides a selection of compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.
    Type: Application
    Filed: September 21, 2021
    Publication date: January 6, 2022
    Inventors: Rebecca Louise Davie, Hannah Joy Edwards, David Michael Evans, Simon Teanby Hodgson, Stephen John Pethen, David Philip Rooker
  • Patent number: 11198691
    Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: December 14, 2021
    Assignee: KalVista Pharmaceuticals Limited
    Inventors: Rebecca Louise Davie, Hannah Joy Edwards, David Michael Evans, Simon Teanby Hodgson
  • Patent number: 11180484
    Abstract: The present invention provides a selection of compounds of formula (I): (I) compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: November 23, 2021
    Assignee: KalVista Pharmaceuticals Limited
    Inventors: Rebecca Louise Davie, Hanna Joy Edwards, David Michael Evans, Simon Teanby Hodgson, Stephen John Pethen, David Philip Rooker