Patents by Inventor David Michael SIMPSON

David Michael SIMPSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2',3'-Diacetyluridine Substituted with Acetoacetyl at the 5' Position
    Publication number: 20260159541
    Abstract: 5?-O-(Acetoacetyl)-2?,3?-di-O-acetyluridine is useful in the treatment or prevention of disorders characterized by cerebral metabolic energy failure or diminished mitochondrial energy reserve capacity.
    Type: Application
    Filed: February 12, 2026
    Publication date: June 11, 2026
    Inventors: Reid Warren VON BORSTEL, David Michael SIMPSON, Rolando Alejandro GARCIA GARCIA
  • Imidazoquinoline compound having anti-inflammatory, antifugal, antiparasitic, and anticancer activity
    Patent number: 12649739
    Abstract: An imidazoquinoline compound having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer is described.
    Type: Grant
    Filed: December 9, 2021
    Date of Patent: June 9, 2026
    Assignee: PHARMA CINQ, LLC
    Inventors: David Michael Simpson, Reid Warren Von Borstel, Rolando Alejandro Garcia Garcia
  • 5?-O-phenylacetyluridine and therapeutic use
    Patent number: 12630580
    Abstract: 5?-O-Phenylacetyluridine effectively delivers both phenylacetate and uridine to a subject. It can be used to treat hepatic encephalopathy and genetic disorders of the hepatic nitrogen cycle.
    Type: Grant
    Filed: November 30, 2021
    Date of Patent: May 19, 2026
    Assignee: PHARMA CINQ, LLC
    Inventors: Rolando Alejandro Garcia Garcia, Joel A. Saydoff, David Michael Simpson, Reid Warren von Borstel
  • 2?,3?-diacetyluridine substituted with acetoacetyl at the 5? position
    Patent number: 12577270
    Abstract: 5?-O-(Acetoacetyl)-2?,3?-di-O-acetyluridine is useful in the treatment or prevention of disorders characterized by cerebral metabolic energy failure or diminished mitochondrial energy reserve capacity.
    Type: Grant
    Filed: September 14, 2021
    Date of Patent: March 17, 2026
    Assignee: PHARMA CINQ, LLC
    Inventors: Reid Warren Von Borstel, David Michael Simpson, Rolando Alejandro Garcia Garcia
  • (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS
    Publication number: 20260042731
    Abstract: This disclosure includes pesticidal compounds, compositions, and related agricultural methods.
    Type: Application
    Filed: August 3, 2023
    Publication date: February 12, 2026
    Applicant: CORTEVA AGRISCIENCE LLC
    Inventors: JEREMY KISTER, MEI LI, DAVID MICHAEL SIMPSON, BIN WEI
  • Imidazoquinolyl compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity
    Patent number: 12139483
    Abstract: Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: November 12, 2024
    Assignee: Pharma Cinq, LLC
    Inventors: David Michael Simpson, Dennis Bryan Zerby, Ming Lu, Reid Warren Von Borstel, Rui Li, Julian Reading, Stephen Wolpe
  • COMPOSITIONS AND COMPOUNDS FOR CO-DELIVERY OF URIDINE AND KETOLEUCINE
    Publication number: 20240158431
    Abstract: Compounds and compositions that deliver both uridine and ketoleucine are useful in treating disorders characterized by diminished muscle strength or diminished muscle lean mass. One such a compound is 5?-O-ketoleucyl-2?,3?-di-O-acetyluridine.
    Type: Application
    Filed: February 2, 2022
    Publication date: May 16, 2024
    Inventors: Reid Warren VON BORSTEL, David Michael SIMPSON, Rolando Alejandro GARCIA GARCIA
  • 5'-O-Phenylacetyluridine and therapeutic use
    Publication number: 20230416292
    Abstract: 5?-O-Phenylacetyluridine effectively delivers both phenylacetate and uridine to a subject. It can be used to treat hepatic encephalopathy and genetic disorders of the hepatic nitrogen cycle.
    Type: Application
    Filed: November 30, 2021
    Publication date: December 28, 2023
    Inventors: ROLANDO ALEJANDRO GARCIA GARCIA, Joel A. SAYDOFF, David Michael SIMPSON, Reid Warren VON BORSTEL
  • IMIDAZOQUINOLINE COMPOUND HAVING ANTI-INFLAMMATORY, ANTIFUGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY
    Publication number: 20230416244
    Abstract: An imidazoquinoline compound having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer is described.
    Type: Application
    Filed: December 9, 2021
    Publication date: December 28, 2023
    Inventors: DAVID MICHAEL SIMPSON, Reid Warren VON BORSTEL, Rolando Alejandro GARCIA GARCIA
  • IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY
    Publication number: 20210163476
    Abstract: Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.
    Type: Application
    Filed: February 16, 2021
    Publication date: June 3, 2021
    Inventors: David Michael SIMPSON, Dennis Bryan ZERBY, Ming LU, Reid Warren VON BORSTEL, Rui LI, Julian READING, Stephen WOLPE