Patent number: 11952408
Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.
Type:
Grant
Filed:
September 28, 2018
Date of Patent:
April 9, 2024
Assignees:
Juno Therapeutics, Inc., Editas Medicine, Inc.
Inventors:
Cameron Brandt, Brian Belmont, Christopher Borges, Stephen Michael Burleigh, Alexandra Croft, Stephen Jacob Goldfless, David Jeffrey Huss, Yue Jiang, Timothy G. Johnstone, David Koppstein, Hieu Nguyen, Christopher Heath Nye, Haley Peper, Blythe D. Sather, Sonia Timberlake, Dean Y. Toy, Queenie Vong, Gordon Grant Welstead, James Sissons
Publication number: 20240108844
Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.
Type:
Application
Filed:
September 20, 2023
Publication date:
April 4, 2024
Inventors:
Hamish Adrian OSBORNE, Gavin Walsh Millar, Stephen David Evans, Bruce Gordon Holyoake, James William Stanton, David Leon McCauley, Gareth Thomas McDermott, Nicholas James Michael McKenna, Myfanwy Jane Antica Norton, Adrian John Elsworth, Michael John Andresen, Jonathan Andrew George Lambert, Sandeep Singh Gurm, Tessa Hazel Paris, Joseph Nathaniel Griffiths, Ping Si, Christopher Gareth Sims, Elmo Benson Stoks, Dexter Chi Lun Cheung, Peter Alan Seekup, Po-Yen Liu, Richard Edward Lang, Paul James Tonkin, Ian Lee Wai Kwan