Patents by Inventor David Millan

David Millan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Caspase inhibitors and uses thereof
    Patent number: 8129381
    Abstract: The present invention relates to compounds of formula I: useful as inhibitors of caspases. The present invention also provides pharmaceutically acceptable compositions comprising said compounds, processes for preparing the compounds, and methods of using the compounds and compositions in the treatment of various diseases, conditions, or disorders.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: March 6, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Ronald Knegtel, Michael Mortimore, John Studley, David Millan
  • CASPASE INHIBITORS AND USES THEREOF
    Publication number: 20090281128
    Abstract: The present invention relates to compounds of formula I: useful as inhibitors of caspases. The present invention also provides pharmaceutically acceptable compositions comprising said compounds, processes for preparing the compounds, and methods of using the compounds and compositions in the treatment of various diseases, conditions, or disorders.
    Type: Application
    Filed: May 12, 2009
    Publication date: November 12, 2009
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Ronald Knegtel, Michael Mortimore, John Studley, David Millan
  • Caspase inhibitors and uses thereof
    Patent number: 7553852
    Abstract: The present invention relates to compounds of formula I: useful as inhibitors of caspases. The present invention also provides pharmaceutically acceptable compositions comprising said compounds, processes for preparing the compounds, and methods of using the compounds and compositions in the treatment of various diseases, conditions, or disorders.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: June 30, 2009
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Ronald Knegtel, Michael Mortimore, John Studley, David Millan
  • Methods for treating vascular diseases
    Publication number: 20070010541
    Abstract: The invention includes methods of treating or preventing vascular disease or promoting vascular growth or development. The methods can be used in the treatment of diseases associated with ischemia, such as heart attack and stroke.
    Type: Application
    Filed: June 30, 2004
    Publication date: January 11, 2007
    Applicant: The General Hospital Corporation
    Inventors: Randall Peterson, Calum Macrae, Stanley Shaw, David Millan, Travis Peterson, Mark Fishman
  • Triazolopyridinylsulfanyl derivatives as p38 MAP kinase inhibitors
    Publication number: 20060035922
    Abstract: A compound of formula (I), or a pharmaceutically acceptable salt and/or solvate (including hydrate) thereof; and the use of a compound of formula (I) in the treatment of a TNF-mediated disease, disorder, or condition, or a p38-mediated disease, disorder, or condition, in particular the allergic and non-allergic airways diseases, more particularly obstructive or inflammatory airways diseases, preferably chronic obstructive pulmonary disease.
    Type: Application
    Filed: August 10, 2005
    Publication date: February 16, 2006
    Inventors: John Mathias, David Millan, Russell Lewthwaite, Christopher Phillips
  • Caspase inhibitors and uses thereof
    Publication number: 20040072850
    Abstract: The present invention relates to compounds of formula I: 1
    Type: Application
    Filed: June 27, 2003
    Publication date: April 15, 2004
    Inventors: Ronald Knegtel, Michael Mortimore, John Studley, David Millan