Patents by Inventor David Mishler

David Mishler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230302220
    Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range.
    Type: Application
    Filed: May 15, 2023
    Publication date: September 28, 2023
    Inventors: Martin Uram, Michael Yanniello, Barry Tucker, David Mishler, Edward Rhinehart, Mark Trocki, Arthur Uber, III, John Brosovich
  • Patent number: 11648346
    Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: May 16, 2023
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Arthur Uber, III, Michael Yanniello, Barry Tucker, David Mishler, Edward Rhinehart, Mark Trocki, Martin Uram, John Brosovich
  • Publication number: 20200078518
    Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range.
    Type: Application
    Filed: November 18, 2019
    Publication date: March 12, 2020
    Inventors: ARTHUR UBER, III, MICHAEL YANNIELLO, BARRY TUCKER, DAVID MISHLER, EDWARD RHINEHART, MARK TROCKI, MARTIN URAM, KEVIN COWAN, JOHN BROSOVICH
  • Patent number: 10478558
    Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: November 19, 2019
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Martin J. Uram, Michael J. Yanniello, Barry L. Tucker, David A. Mishler, Edward J. Rhinehart, Mark Trocki, Arthur E. Uber, III, Kevin P. Cowan, John A. Brosovich
  • Publication number: 20190108903
    Abstract: Provided is a method of collecting and managing information relating to medical diagnostic procedures which includes collecting objective information about a plurality of procedures and subjective information about the results of those procedures. The objective information provides information about the parameters of the procedure and the patient who underwent the procedure while the subjective information includes an assessment of the quality of the results of the procedure. This information can be stored in a database. The database can be accessed and the information therein used in connection with understanding the results of past procedures and planning for future procedures.
    Type: Application
    Filed: September 11, 2018
    Publication date: April 11, 2019
    Inventors: JOHN F. KALAFUT, DAVID A. MISHLER, SRIDHAR R. BALASUBRAMANIAN, JOHN A. BROSOVICH, FREDERICK P. WINDHAM
  • Patent number: 10166326
    Abstract: A system for enabling delivery of fluid in an injection procedure to be performed on a patient in connection with a diagnostic imaging procedure is disclosed. The system includes a controller operably associated with at least one pressurizing mechanism though which at least one of a first and a second fluid contained within at least one fluid container is injectable into the patient. The first fluid includes a contrast enhancing agent while the second fluid does not. The controller includes a programming system for programming an injection protocol having a plurality of phases to effect enhancement of at least one region of interest of the patient over a scan duration of the diagnostic imaging procedure. The programming system includes an algorithm that enables computation of a ratio of the first and second fluids based on at least a peak enhancement that occurs in at least one region of interest.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: January 1, 2019
    Assignee: BAYER HEALTHCARE LLC
    Inventors: John F. Kalafut, David A. Mishler
  • Patent number: 10078725
    Abstract: Provided is a method of collecting and managing information relating to medical diagnostic procedures which includes collecting objective information about a plurality of procedures and subjective information about the results of those procedures. The objective information provides information about the parameters of the procedure and the patient who underwent the procedure while the subjective information includes an assessment of the quality of the results of the procedure. This information can be stored in a database. The database can be accessed and the information therein used in connection with understanding the results of past procedures and planning for future procedures.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: September 18, 2018
    Assignee: BAYER HEALTHCARE LLC
    Inventors: John F. Kalafut, David A. Mishler, Sridhar R. Balasubramanian, John A. Brosovich, Frederick P. Windham
  • Patent number: 9950107
    Abstract: A system and method of managing workflow for a variety of injection procedures preferably includes a display that provides a graphical representation of the steps required to initiate an injection procedure. The system can, for example, set forth a suggested order or sequence for the steps to be completed, and display the suggested sequence of steps graphically. Various steps may optionally require completion of ancillary operations as a requirement for completion of the selected step.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: April 24, 2018
    Assignee: BAYER HEALTHCARE LLC
    Inventors: John F. Kalafut, David A. Mishler
  • Publication number: 20170087303
    Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range.
    Type: Application
    Filed: December 12, 2016
    Publication date: March 30, 2017
    Inventors: MARTIN J. URAM, MICHAEL J. YANNIELLO, BARRY L. TUCKER, DAVID A. MISHLER, EDWARD J. RHINEHART, MARK TROCKI, ARTHUR E. UBER, III, KEVIN P. COWAN, JOHN A. BROSOVICH
  • Patent number: 9517305
    Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: December 13, 2016
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Martin J. Uram, Michael J. Yanniello, Barry L. Tucker, David A. Mishler, Edward J. Rhinehart, Mark Trocki, Arthur E. Uber, III, Kevin P. Cowan, John A. Brosovich
  • Patent number: 9238099
    Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: January 19, 2016
    Assignee: Bayer HealthCare LLC
    Inventors: John F. Kalafut, David A. Mishler
  • Publication number: 20150182687
    Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.
    Type: Application
    Filed: March 13, 2015
    Publication date: July 2, 2015
    Inventors: John F. Kalafut, David A. Mishler
  • Publication number: 20150100572
    Abstract: Provided is a method of collecting and managing information relating to medical diagnostic procedures which includes collecting objective information about a plurality of procedures and subjective information about the results of those procedures. The objective information provides information about the parameters of the procedure and the patient who underwent the procedure while the subjective information includes an assessment of the quality of the results of the procedure. This information can be stored in a database. The database can be accessed and the information therein used in connection with understanding the results of past procedures and planning for future procedures.
    Type: Application
    Filed: November 19, 2012
    Publication date: April 9, 2015
    Inventors: John F. Kalafut, David A. Mishler, Sridhar R. Balasubramanian, John A. Brosovich, Frederick P. Windham
  • Publication number: 20140276550
    Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: MEDRAD, INC.
    Inventors: Martin J. URAM, Michael J. YANNIELLO, Barry L. TUCKER, David A. MISHLER, Edward J. RHINEHART
  • Publication number: 20140276379
    Abstract: A configurable fluid delivery system and methods for its use are disclosed. The system may include one or more control units, fluid delivery units, fluid actuator units, and disposable units. Data sources and sensors on each of the delivery units, actuator units, and disposable units may provide data to the control unit, thereby identifying the components along with the manner in which they may be configured. The control unit may notify a user regarding the status of any one or more of the delivery, actuator, and disposable units to indicate their appropriateness for delivering a fluid according to one or more selected procedures and protocols. Also disclosed are methods by which the configurable fluid delivery unit may provide data to a user to assist the user in assembling and testing a particular fluid delivery configuration for a specific use.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: MEDRAD, INC.
    Inventors: Martin J. URAM, Arthur E. UBER, III, Kevin P. COWAN, John A. BROSOVICH, David A. MISHLER, Edward J. RHINEHART, Michael J. YANNIELLO, Mark TROCKI, Barry L. TUCKER
  • Publication number: 20140230368
    Abstract: Systems and methods for enabling high fluid rate injections are disclosed. The system includes a hollow dip tube, an introducer and a sharp tip-end. The introducer has a hollow sleeve that includes an opening at a proximal end. The sharp-tip end is located at a distal end of the introducer and is configured to pierce a septum of a container. The introducer is configured to receive the dip tube through the opening. Fluid may be withdrawn from the container through the dip tube upon insertion. In some cases, the dip tube separates the tip-end from the introducer when it is inserted through the opening. In other cases, the tip-end remains seated in the introducer and allows fluid to pass through it as it is withdrawn from the container.
    Type: Application
    Filed: February 21, 2013
    Publication date: August 21, 2014
    Applicant: MEDRAD, INC.
    Inventors: Mark TROCKI, David A. MISHLER
  • Patent number: 8182444
    Abstract: A system for delivering a fluid comprising cells to tissue of a patient includes a container holding an injection fluid and a powered drive. A sensor system provides a measurement indicative of at least shear forces on the cells to a control system. Based at least in part on this measurement, the control system is adapted to transmit a control signal to the powered drive for pressurizing the contents of the container to deposit cells within the tissue of a patient via a fluid path and a patient interface. As an example, the cells can be pregenitor or stem cells.
    Type: Grant
    Filed: November 6, 2006
    Date of Patent: May 22, 2012
    Assignee: Medrad, Inc.
    Inventors: Arthur E. Uber, III, Alan D. Hirschman, David M. Griffiths, David M. Reilly, Kevin P. Cowan, Barry L. Tucker, David Mishler
  • Publication number: 20120016233
    Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.
    Type: Application
    Filed: July 20, 2011
    Publication date: January 19, 2012
    Inventors: John F. Kalafut, David A. Mishler
  • Patent number: 7925330
    Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a controller operably associated with the at least one pressurizing mechanism. The controller includes a programming system to allow programming of an injection protocol including, for example, a plurality of phases. At least one parameter generator is provided to determine parameters of at least one of the plurality of phases of the protocol based at least in part upon a type of the injection procedure.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: April 12, 2011
    Assignee: MEDRAD, Inc.
    Inventors: John F. Kalafut, David A. Mishler
  • Patent number: 7670315
    Abstract: An injector for injection a fluid into a patient, including: a first pressurizing mechanism adapted to operatively connect with a first fluid container to pressurize fluid therein; at least a second pressurizing mechanism to operatively connect with a second fluid container to pressurize a fluid therein; a single drive; and a transmission to control how power from the drive is distributed to the first pressurizing mechanism of the first container and to the second pressurizing mechanism of the second container to control injection of fluid from the first container and from the second container. The drive can, for example, be an electric motor or other drive.
    Type: Grant
    Filed: January 21, 2006
    Date of Patent: March 2, 2010
    Assignee: Medrad, Inc.
    Inventors: Kevin P. Cowan, David M. Reilly, Joseph J. Fularz, Paul J. Swartz, Mark Trocki, David A. Mishler