Patents by Inventor David Mishler
David Mishler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230302220Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range.Type: ApplicationFiled: May 15, 2023Publication date: September 28, 2023Inventors: Martin Uram, Michael Yanniello, Barry Tucker, David Mishler, Edward Rhinehart, Mark Trocki, Arthur Uber, III, John Brosovich
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Patent number: 11648346Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.Type: GrantFiled: November 18, 2019Date of Patent: May 16, 2023Assignee: BAYER HEALTHCARE LLCInventors: Arthur Uber, III, Michael Yanniello, Barry Tucker, David Mishler, Edward Rhinehart, Mark Trocki, Martin Uram, John Brosovich
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Publication number: 20200078518Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range.Type: ApplicationFiled: November 18, 2019Publication date: March 12, 2020Inventors: ARTHUR UBER, III, MICHAEL YANNIELLO, BARRY TUCKER, DAVID MISHLER, EDWARD RHINEHART, MARK TROCKI, MARTIN URAM, KEVIN COWAN, JOHN BROSOVICH
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Patent number: 10478558Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.Type: GrantFiled: December 12, 2016Date of Patent: November 19, 2019Assignee: BAYER HEALTHCARE LLCInventors: Martin J. Uram, Michael J. Yanniello, Barry L. Tucker, David A. Mishler, Edward J. Rhinehart, Mark Trocki, Arthur E. Uber, III, Kevin P. Cowan, John A. Brosovich
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Publication number: 20190108903Abstract: Provided is a method of collecting and managing information relating to medical diagnostic procedures which includes collecting objective information about a plurality of procedures and subjective information about the results of those procedures. The objective information provides information about the parameters of the procedure and the patient who underwent the procedure while the subjective information includes an assessment of the quality of the results of the procedure. This information can be stored in a database. The database can be accessed and the information therein used in connection with understanding the results of past procedures and planning for future procedures.Type: ApplicationFiled: September 11, 2018Publication date: April 11, 2019Inventors: JOHN F. KALAFUT, DAVID A. MISHLER, SRIDHAR R. BALASUBRAMANIAN, JOHN A. BROSOVICH, FREDERICK P. WINDHAM
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Patent number: 10166326Abstract: A system for enabling delivery of fluid in an injection procedure to be performed on a patient in connection with a diagnostic imaging procedure is disclosed. The system includes a controller operably associated with at least one pressurizing mechanism though which at least one of a first and a second fluid contained within at least one fluid container is injectable into the patient. The first fluid includes a contrast enhancing agent while the second fluid does not. The controller includes a programming system for programming an injection protocol having a plurality of phases to effect enhancement of at least one region of interest of the patient over a scan duration of the diagnostic imaging procedure. The programming system includes an algorithm that enables computation of a ratio of the first and second fluids based on at least a peak enhancement that occurs in at least one region of interest.Type: GrantFiled: March 13, 2015Date of Patent: January 1, 2019Assignee: BAYER HEALTHCARE LLCInventors: John F. Kalafut, David A. Mishler
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Patent number: 10078725Abstract: Provided is a method of collecting and managing information relating to medical diagnostic procedures which includes collecting objective information about a plurality of procedures and subjective information about the results of those procedures. The objective information provides information about the parameters of the procedure and the patient who underwent the procedure while the subjective information includes an assessment of the quality of the results of the procedure. This information can be stored in a database. The database can be accessed and the information therein used in connection with understanding the results of past procedures and planning for future procedures.Type: GrantFiled: November 19, 2012Date of Patent: September 18, 2018Assignee: BAYER HEALTHCARE LLCInventors: John F. Kalafut, David A. Mishler, Sridhar R. Balasubramanian, John A. Brosovich, Frederick P. Windham
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Patent number: 9950107Abstract: A system and method of managing workflow for a variety of injection procedures preferably includes a display that provides a graphical representation of the steps required to initiate an injection procedure. The system can, for example, set forth a suggested order or sequence for the steps to be completed, and display the suggested sequence of steps graphically. Various steps may optionally require completion of ancillary operations as a requirement for completion of the selected step.Type: GrantFiled: July 20, 2011Date of Patent: April 24, 2018Assignee: BAYER HEALTHCARE LLCInventors: John F. Kalafut, David A. Mishler
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Publication number: 20170087303Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range.Type: ApplicationFiled: December 12, 2016Publication date: March 30, 2017Inventors: MARTIN J. URAM, MICHAEL J. YANNIELLO, BARRY L. TUCKER, DAVID A. MISHLER, EDWARD J. RHINEHART, MARK TROCKI, ARTHUR E. UBER, III, KEVIN P. COWAN, JOHN A. BROSOVICH
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Patent number: 9517305Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.Type: GrantFiled: March 15, 2013Date of Patent: December 13, 2016Assignee: BAYER HEALTHCARE LLCInventors: Martin J. Uram, Michael J. Yanniello, Barry L. Tucker, David A. Mishler, Edward J. Rhinehart, Mark Trocki, Arthur E. Uber, III, Kevin P. Cowan, John A. Brosovich
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Patent number: 9238099Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.Type: GrantFiled: March 27, 2007Date of Patent: January 19, 2016Assignee: Bayer HealthCare LLCInventors: John F. Kalafut, David A. Mishler
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Publication number: 20150182687Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.Type: ApplicationFiled: March 13, 2015Publication date: July 2, 2015Inventors: John F. Kalafut, David A. Mishler
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Publication number: 20150100572Abstract: Provided is a method of collecting and managing information relating to medical diagnostic procedures which includes collecting objective information about a plurality of procedures and subjective information about the results of those procedures. The objective information provides information about the parameters of the procedure and the patient who underwent the procedure while the subjective information includes an assessment of the quality of the results of the procedure. This information can be stored in a database. The database can be accessed and the information therein used in connection with understanding the results of past procedures and planning for future procedures.Type: ApplicationFiled: November 19, 2012Publication date: April 9, 2015Inventors: John F. Kalafut, David A. Mishler, Sridhar R. Balasubramanian, John A. Brosovich, Frederick P. Windham
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Publication number: 20140276550Abstract: Systems and methods for intelligently delivering fluid to a targeted tissue. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Applicant: MEDRAD, INC.Inventors: Martin J. URAM, Michael J. YANNIELLO, Barry L. TUCKER, David A. MISHLER, Edward J. RHINEHART
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Publication number: 20140276379Abstract: A configurable fluid delivery system and methods for its use are disclosed. The system may include one or more control units, fluid delivery units, fluid actuator units, and disposable units. Data sources and sensors on each of the delivery units, actuator units, and disposable units may provide data to the control unit, thereby identifying the components along with the manner in which they may be configured. The control unit may notify a user regarding the status of any one or more of the delivery, actuator, and disposable units to indicate their appropriateness for delivering a fluid according to one or more selected procedures and protocols. Also disclosed are methods by which the configurable fluid delivery unit may provide data to a user to assist the user in assembling and testing a particular fluid delivery configuration for a specific use.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Applicant: MEDRAD, INC.Inventors: Martin J. URAM, Arthur E. UBER, III, Kevin P. COWAN, John A. BROSOVICH, David A. MISHLER, Edward J. RHINEHART, Michael J. YANNIELLO, Mark TROCKI, Barry L. TUCKER
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Publication number: 20140230368Abstract: Systems and methods for enabling high fluid rate injections are disclosed. The system includes a hollow dip tube, an introducer and a sharp tip-end. The introducer has a hollow sleeve that includes an opening at a proximal end. The sharp-tip end is located at a distal end of the introducer and is configured to pierce a septum of a container. The introducer is configured to receive the dip tube through the opening. Fluid may be withdrawn from the container through the dip tube upon insertion. In some cases, the dip tube separates the tip-end from the introducer when it is inserted through the opening. In other cases, the tip-end remains seated in the introducer and allows fluid to pass through it as it is withdrawn from the container.Type: ApplicationFiled: February 21, 2013Publication date: August 21, 2014Applicant: MEDRAD, INC.Inventors: Mark TROCKI, David A. MISHLER
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Patent number: 8182444Abstract: A system for delivering a fluid comprising cells to tissue of a patient includes a container holding an injection fluid and a powered drive. A sensor system provides a measurement indicative of at least shear forces on the cells to a control system. Based at least in part on this measurement, the control system is adapted to transmit a control signal to the powered drive for pressurizing the contents of the container to deposit cells within the tissue of a patient via a fluid path and a patient interface. As an example, the cells can be pregenitor or stem cells.Type: GrantFiled: November 6, 2006Date of Patent: May 22, 2012Assignee: Medrad, Inc.Inventors: Arthur E. Uber, III, Alan D. Hirschman, David M. Griffiths, David M. Reilly, Kevin P. Cowan, Barry L. Tucker, David Mishler
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Publication number: 20120016233Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a pressure modeling system adapted to predict a pressure to be generated at one or more points in the injection fluid path during planned injection procedure based upon variables associated with an injection protocol.Type: ApplicationFiled: July 20, 2011Publication date: January 19, 2012Inventors: John F. Kalafut, David A. Mishler
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Patent number: 7925330Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a controller operably associated with the at least one pressurizing mechanism. The controller includes a programming system to allow programming of an injection protocol including, for example, a plurality of phases. At least one parameter generator is provided to determine parameters of at least one of the plurality of phases of the protocol based at least in part upon a type of the injection procedure.Type: GrantFiled: November 23, 2005Date of Patent: April 12, 2011Assignee: MEDRAD, Inc.Inventors: John F. Kalafut, David A. Mishler
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Patent number: 7670315Abstract: An injector for injection a fluid into a patient, including: a first pressurizing mechanism adapted to operatively connect with a first fluid container to pressurize fluid therein; at least a second pressurizing mechanism to operatively connect with a second fluid container to pressurize a fluid therein; a single drive; and a transmission to control how power from the drive is distributed to the first pressurizing mechanism of the first container and to the second pressurizing mechanism of the second container to control injection of fluid from the first container and from the second container. The drive can, for example, be an electric motor or other drive.Type: GrantFiled: January 21, 2006Date of Patent: March 2, 2010Assignee: Medrad, Inc.Inventors: Kevin P. Cowan, David M. Reilly, Joseph J. Fularz, Paul J. Swartz, Mark Trocki, David A. Mishler