Abstract: A bag or pouch container for use in cooking foodstuffs in a microwave oven, comprising two sheets of plastics material bonded or welded together along its edges (2) to define a foodstuff receiving and/or containing interior and being closed or closable to permit cooking under pressure i.e. at above atmospheric pressure, said sheets also being bonded or welded together along a bonding line or lines (4) extending between edge regions to define one or more compartments (5, 6) within the container for receiving and/or containing foodstuffs or other contents, with said line or lines being separable or rupturable at a desired temperature and/or pressure to permit flow of one foodstuff into the other compartment, and a pressure relief valve or means (17) operable to relieve pressure within the container during cooking whilst permitting cooking to continue thereafter at a pressure above atmospheric pressure.

Abstract: The present invention relates to a series of substituted indole derivatives of the formula I: wherein R, R1, R2, R3, R4, X and Y are as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are inhibitors of poly(adenosine 5?-diphosphate ribose) polymerase (PARP) and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases, including diseases associated with the central nervous system and cardiovascular disorders.