Abstract: A robotic system to control multiple robots to perform a task cooperatively is disclosed. A first robot determines to perform a task cooperatively with a second robot, moves independently to a first grasp position to grasp an object associated with the task, receives an indication that the second robot is prepared to perform the task cooperatively, and moves the object independently of the second robot in a leader mode along a trajectory determined by the first robot. The second robot assists the first robot in performing the task cooperatively, at least in part by moving independently to a second grasp position, grasping the object, and cooperating with the first robot to move the object, at least in part by operating in a follower mode of operation to maintain engagement with the object as the first robot moves the object along the trajectory.

Abstract: The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).

Abstract: Provided are compounds of Formula (I): wherein R1, R2, X, Ring A, Ring B, and Ring C are as defined herein. Compounds of Formula (I) are useful as inhibitors of DNA-PK. Also provided are pharmaceutical compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various diseases, conditions, and disorders.

Abstract: A robotic system comprising an end effector-mounted sensor is disclosed. In various embodiments, a robotic arm is manipulated to move a sensor to a position such that an object of interest is within a read range of the sensor. A sensor data read by the sensor is received via a communication interface. The sensor data is used to determine an attribute of the object; and the determined attribute of the object is used to determine a plan to grasp and move the object.

Abstract: Provided are compositions and methods for treating cancer using administration of certain volumes of CpG oligonucleotides (CpG ODN) and, optionally, administration of a checkpoint inhibitor such as an anti-PD-1 antibody, an anti-PD-L1 antibody, and/or an anti-CTLA-4 antibody. In preferred embodiments, the CpG ODN are selected based on their propensity to induce high amounts of interferon alpha (IFN-a) and T-cell activation relative to interleukin-10 (IL-10) and B-cell activation. In certain embodiments, the methods further include pretreatment with radiotherapy, to potentiate the combination immunotherapy.

Abstract: Embodiments described herein relate to suppressors for reducing or eliminating sound, flash, and/or heat generated by firearms while discharging projectiles. The suppressor includes a unitary structure containing a cone shaped nozzle disposed at one end of a body. The body has a plurality of baffles surrounding a central bore, a breech end opposite a faceplate, and a plurality of cooling channels spanning a length of the body. Each cooling channel has a first opening at the breech end and a second opening at the faceplate. The unitary structure further contains an outer ring spanning from the breech end to at least the faceplate, a longitudinal wall spanning from the breech end to the faceplate, and a plurality of radially oriented walls extending between the longitudinal wall and the outer ring. The plurality of cooling channels is disposed between the longitudinal wall, the outer ring, and the radially oriented walls.

Abstract: A system and method for displaying images of internal anatomy includes an image processing device configured to provide high resolution images of the surgical field from low resolution scans during the procedure. The image processing device digitally manipulates a previously-obtained high resolution baseline image to produce many representative images based on permutations of movement of the baseline image. During the procedure a representative image is selected having an acceptable degree of correlation to the new low resolution image. The selected representative image and the new image are merged to provide a higher resolution image of the surgical field. The image processing device is also configured to provide interactive movement of the displayed image based on movement of the imaging device, and to permit placement of annotations on the displayed image to facilitate communication between the radiology technician and the surgeon.

Abstract: A polymer coating/ring is employed to aid in the sealing and connection of modular elements used in body flow lumens for the exclusion and bypass of diseased regions of the flow lumen, such as where aneurysm occurs adjacent to branching blood vessels.

Abstract: An electric pushback vehicle includes a frame having a forward portion and a rear portion. The vehicle further includes front drive axle and a rear drive axle configured to communicate power to ground engaging members. A traction battery is housed within the electric pushback vehicle and provides electric power to an electric motor to drive an output shaft. A transmission is connected to receive mechanical power from the electric motor through a torque converter.

Abstract: In general, the subject matter described in this disclosure can be embodied in a display panel. The display panel includes a first area of multiple pixels that has a first density of light emitting diodes (LEDs), and that has an equal representation of LEDs of a first color, a second color, and a third color. Each pixel in the first area has: (i) a first sub-pixel comprising an LED of the first color, (ii) a second sub-pixel comprising an LED of the second color, and (iii) a third sub-pixel comprising an LED of the third color. The display panel includes a second area of multiple pixels that borders the first area, that has a second density of LEDs that is lower than the first density, and that has an unequal representation of LEDS of the first color, the second color, and the third color.

Abstract: Disclosed herein is a method for treating a respiratory disease in a patient. The method comprises administering by inhalation a therapeutically effective combination of a glycoprotein affecting protease and a sputum-degrading agent.

Abstract: Distance-sensing techniques (between probes and a sample) utilize at least one of squeeze-film damping and temperature sensing for scanning probe microscopy. Squeeze-film damping may be used for “approach;” that is, z-position detection. It may also be used for “imaging;” that is, to obtain a topographic map of the surface of a sample.

Abstract: An augmented reality (AR) platform for the Internet of Things (IoT) is disclosed. The AR platform enables a user to associate AR objects with IoT devices. These associations may further enable a user to direct a control input to a particular IoT device and receive outputs such as sensor measurements or state information from the IoT device via interaction with an associated AR object. These AR objects may be perceived by the user via a client device, such as via an AR viewer or other human interface. The AR platform further enables users to create shareable objects that define an association among or between multiple AR objects and their IoT devices that can be shared with and modified by other users.

Abstract: The present disclosure seeks to provide a handpiece configuration for a surgical instrument such as an electrosurgical instrument to reduce the risk of a burn to the operator handling the handpiece. In particular, the present disclosure firstly provides an inner moulding in the handpiece for housing a motor and a suction path of the electrosurgical instrument. The inner moulding comprises a thermal conduction path between the motor and the suction path for the purpose of transferring heat generated from the motor to the exiting irrigation fluid in the suction path. The handpiece is further configured to comprise a thermally insulating outer casing surrounding the inner moulding. This configuration of the handpiece enables heat transfer from the motor to the irrigation fluid in the suction path while keeping the external surface of the handpiece cool.

Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant or a Glycine plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal or soy seeds and/or cereal or soy seedlings) with heterologous seed-derived bacterial endophytes.

Abstract: An apparatus for use with a surgical instrument having a hollow shaft for transferring fluid and/or debris generated during use of the surgical instrument. The apparatus comprises: a drive unit comprising a driving part configured to generate a driving force for driving the surgical instrument, and a driven part driven by the driving part to transfer the driving force to the surgical instrument; and a channel arranged to receive the hollow shaft of the surgical instrument, the channel extending through the driven part of the drive unit.

Abstract: A display panel includes a first set of pixels that each include a respective red sub-pixel and a respective green sub-pixel and a second set of pixels that each include a respective blue sub-pixel and a respective green sub-pixel, where the first set of pixels and the second set of pixels are arranged on the display panel such that at least one side of each of the pixels in the first set of pixels is adjacent to at least one of the pixels in the second set of pixels, at least one side of each of the pixels in the first set of pixels is not adjacent to any pixel, and the green sub-pixels are arranged on the display panel such that the green sub-pixels are evenly distributed in the display panel.

Abstract: An augmented reality (AR) platform supports concurrent operation of multiple AR applications developed by third-party software developers. The AR platform may include an application programming interface (API) that third-party software developers can use to integrate features of the AR platform into the overall user experience of their AR applications. The AR platform includes a feature set having a variety of AR-specific features that interact with and are accessible to the AR applications or AR layers that define a collection of AR content.