Patents by Inventor David Mrazek

David Mrazek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR SELECTING MEDICATIONS
    Publication number: 20230420139
    Abstract: The invention provides computer assisted methods for selecting an antidepressant medication for a patient. The methods utilize a combination genotype comprising at least three genes to guide medication selection.
    Type: Application
    Filed: February 1, 2023
    Publication date: December 28, 2023
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • METHODS FOR SELECTING MEDICATIONS FOR TREATING PATIENTS HAVING ATTENTION-DEFICIT HYPERACTIVITY DISORDER
    Publication number: 20200080153
    Abstract: Methods for selecting a medication for a patient are described that include determining the patient's genotype for a panel of genes, identifying a phenotype associated with the genotype for each gene, and selecting the medication based on the phenotype.
    Type: Application
    Filed: August 22, 2019
    Publication date: March 12, 2020
    Inventor: David A. Mrazek
  • METHODS FOR SELECTING MEDICATIONS
    Publication number: 20200048712
    Abstract: The invention provides computer assisted methods for selecting an antidepressant medication for a patient. The methods utilize a combination genotype comprising at least three genes to guide medication selection.
    Type: Application
    Filed: May 15, 2019
    Publication date: February 13, 2020
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • Methods for selecting medications for treating patients having attention-deficit hyperactivity disorder
    Patent number: 10435746
    Abstract: Methods for selecting a medication for a patient are described that include determining the patient's genotype for a panel of genes, identifying a phenotype associated with the genotype for each gene, and selecting the medication based on the phenotype.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: October 8, 2019
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: David A. Mrazek, Patricia J. Mrazek
  • Methods for Selecting Medications
    Publication number: 20160237494
    Abstract: The invention provides computer assisted methods for selecting an antidepressant medication for a patient. The methods utilize a combination genotype comprising at least three genes to guide medication selection.
    Type: Application
    Filed: November 13, 2015
    Publication date: August 18, 2016
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • Methods for selecting medications
    Patent number: 9111028
    Abstract: The invention provides methods for selecting and administering antidepressant medications to a patient based upon the patient's combination genotype and phenotype for a panel of genes.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: August 18, 2015
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • Methods for Selecting Medications
    Publication number: 20150148336
    Abstract: The invention provides methods for selecting and administering antidepressant medications to a patient based upon the patient's combination genotype and phenotype for a panel of genes.
    Type: Application
    Filed: January 30, 2015
    Publication date: May 28, 2015
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype
    Patent number: 8688385
    Abstract: Methods for selecting a medication for a patient are described that include determining the patient's genotype for a panel of genes and selecting the medication based on the genotype. Articles of manufacture also are provided that include nucleic acid molecules for detecting alleles of genes encoding drug metabolizing enzymes and genes encoding products involved in neurotransmission.
    Type: Grant
    Filed: August 2, 2006
    Date of Patent: April 1, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • Methods for Selecting Medications
    Publication number: 20130311202
    Abstract: The invention provides a computer program product for selecting and administering a psychotropic medication for a patient. The computer program product utilizes a combination of genotype and phenotype information to provide the user with accurate guidance regarding the appropriate medication and its use.
    Type: Application
    Filed: March 11, 2013
    Publication date: November 21, 2013
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • Methods for selecting medications
    Patent number: 8401801
    Abstract: Methods for selecting a medication for a patient are described that include determining the patient's genotype for a panel of genes and selecting the medication based on the genotype. Articles of manufacture also are provided that include nucleic acid molecules for detecting alleles of genes encoding drug metabolizing enzymes and genes encoding products involved in neurotransmission.
    Type: Grant
    Filed: February 20, 2004
    Date of Patent: March 19, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • DETERMINING THE PHASE OF DUPLICATED CYP2D6 ALLELES
    Publication number: 20100092970
    Abstract: This document relates to methods and materials involved in detecting duplicated CYP2D6 alleles (e.g., CYP2D6/CYP2D7?CYP2D6 arrangements) in mammals (e.g., humans).
    Type: Application
    Filed: March 7, 2008
    Publication date: April 15, 2010
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: John L. Black, III, Dennis J. O'kane, David A. Mrazek, Whitney Erin Kramer, Denise L. Walker, Pamela K. Fisher
  • Methods for selecting medications
    Publication number: 20080311563
    Abstract: Methods for selecting a medication for a patient are described that include determining the patient's genotype for a panel of genes and selecting the medication based on the genotype. Articles of manufacture also are provided that include nucleic acid molecules for detecting alleles of genes encoding drug metabolizing enzymes and genes encoding products involved in neurotransmission.
    Type: Application
    Filed: August 2, 2006
    Publication date: December 18, 2008
    Inventors: David A. Mrazek, Dennis J. O'Kane, John L. Black
  • Variants of the Serotonin Transporter
    Publication number: 20080081336
    Abstract: Isolated SLC6A4 nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described. Methods for determining whether a subject contains an SLC6A4 sequence variant also are provided.
    Type: Application
    Filed: August 2, 2007
    Publication date: April 3, 2008
    Inventors: David Mrazek, Richard Weinshilboum, Eric Wieben, Linda Pelleymounter, Irene Moon
  • Methods for selecting medications
    Publication number: 20070003931
    Abstract: Methods for selecting a medication for a patient are described that include determining the patient's genotype for a panel of genes and selecting the medication based on the genotype. Articles of manufacture also are provided that include nucleic acid molecules for detecting alleles of genes encoding drug metabolizing enzymes and genes encoding products involved in neurotransmission.
    Type: Application
    Filed: February 20, 2004
    Publication date: January 4, 2007
    Inventors: David Mrazek, Dennis O'Kane, John Black