Abstract: Thermokeratoplasty is applied to achieve a customized reshaping of a cornea, especially, for the treatment of astigmatism. Energy is applied to the cornea in a customized pattern using a specific configuration of two conductors. In one embodiment, an outer conductor and an outer conductor are separated by a gap. When a conducting element is applied to the corneal surface the area of the cornea at the periphery of the inner conductor is subject to an energy pattern with substantially the same shape and dimension as the gap between the inner and outer conductors. The inner and outer conductors may be positioned and shaped to form a gap having any desirable size and/or shape, including non-annular and asymmetrical shapes.

Abstract: The invention provides low molecular weight or polymeric organic materials in which at least one hydrogen atom is replaced by a group of the formula (A) where R is alkyl group, alkoxyalkyl group, alkoxy group, thioalkoxy group, aryl group or alkenyl group, in each of which one or more hydrogen atoms may be replaced and one or more nonadjacent carbon atoms may be replaced. Z is —O—, —S—, —CO—, —COO—, —O—CO— or a bivalent group —(CR1R2)n— in which R1 and R2 are hydrogen, alkyl, alkoxy, alkoxyalkyl or thioalkoxy group, aryl or alkenyl, in each of which one or more hydrogen atoms may be replaced and one or more nonadjacent carbon atoms may be replaced, and n is an integer from 1 to 20. X is a bivalent group —(CR1R2)n— and, with the proviso that the number of these A groups is limited by the maximum number of available substitutable hydrogen atoms.

Abstract: A system for applying therapy to an eye includes an applicator having a conducting element configured to direct energy from an energy source to an application end of the conducting element, where the application end has at least one eye contact portion. A positioning system positions the at least one eye contact portion in stable engagement with the eye surface. The conducting element is disposed within a housing for the applicator and at least one adjustment system is employed to move the conducting element relative to the housing. The at least one adjustment system enables controlled movement of the conducting element and the at least one eye contact portion against the corneal surface. In particular embodiments, sufficient contact between the applicator and the cornea is determined by causing applanation of the cornea. In other embodiments, at least one measurement device is employed to determine when sufficient contact has been established.

Abstract: A system for applying therapy to an eye includes an applicator having a conducting element configured to direct energy from an energy source to an application end of the conducting element, where the application end has an eye contact portion. A positioning system receives the applicator and positions the eye contact portion in stable engagement with the surface of an eye. In some embodiments, the conducting element is disposed within a housing for the applicator and an adjustment system is employed to move the conducting element relative to the housing. The adjustment system enables controlled movement of the conducting element and the eye contact portion against the corneal surface. In particular embodiments, sufficient contact between the applicator and the cornea is determined by causing applanation of the cornea. In other embodiments, a physical measurement device, such as a strain gauge, is employed to determine when sufficient contact has been established.

Abstract: A system for applying therapy to an eye includes an energy source and a conducting element operably connected to the energy source and configured to direct energy from the energy source to an application end of the conducting element. The application end includes an eye contact portion configured to apply the energy to an eye feature and provides a reshaping mold to reshape the eye feature as the eye feature responds to the application of the energy. The eye contact portion may have a concave curvature and may be positioned in direct contact with the eye feature. In addition, the eye feature may be the cornea of the eye. In a particular embodiment, the energy source is an electrical energy source, the conducting element comprises an outer electrode and an inner electrode separated by a gap, and the eye contact portion is positioned on the inner electrode.

Abstract: A system for aligning an eye therapy instrument over a selected area or feature of an eye provides an attachment element that is removably attached to a surface of an eye. A receiving element is coupled to the attachment element and movable relative to the attachment element. The receiving element includes a coupling element configured to operably couple an eye therapy instrument to the receiving element and adjustably move the eye therapy instrument into a selected position with respect to the attachment element. The system makes adjustments to ensure accurate delivery of treatment from the eye therapy device to areas of the eye. In one embodiment, the receiving element allows lateral adjustments to be made along one or more axes. Additionally or alternatively, the receiving element allows angular or rotational adjustments to be made about one or more axes.

Abstract: Heat is generated in corneal fibrils in a cornea of an eye according to a selected pattern. The heat causes the corneal fibrils corresponding to the selected pattern to transition from a first structure to a second structure. The second structure provides a desired reshaping of the cornea. A cross-linking agent is then activated in the region of corneal fibrils according to the selected pattern. The cross-linking agent prevents the corneal fibrils from changing from the second structure. Thus, embodiments stabilize corneal tissue and improve its biomechanical strength after desired structural changes have been achieved in the corneal tissue. Accordingly, the embodiments help to preserve the desired reshaping of the cornea.

Abstract: A system for applying therapy to an eye selectively applies coolant to the corneal surface to minimize heat-related damage to the corneal surface during thermokeratoplasty. Embodiments may include an energy source, a conducting element, a coolant supply, and a coolant delivery system. The conducting element is operably connected to the energy source and extends from a proximal end to a distal end. The conducting element directs energy from the energy source to the distal end, which is positionable at the eye. The coolant delivery system is in communication with the coolant supply and is operable to deliver a micro-controlled pulse of coolant to the distal end.

Abstract: A system for applying therapy to an eye selectively applies coolant to the corneal surface to minimize heat-related damage to the corneal surface during thermokeratoplasty. Embodiments may include an energy source, a conducting element, a coolant supply, and at least one coolant delivery element. The conducting element is operably connected to the energy source and extends from a proximal end to a distal end. The conducting element directs energy from the energy source to the distal end, which is positionable at the eye. The coolant delivery elements are in communication with the coolant supply and are operable to deliver a micro-controlled pulse of coolant to the distal end.

Abstract: An integrated circuit includes a memory interface circuit. The memory interface circuit includes a first interface channel configured to couple to at least one memory device, a second interface channel configured to couple to at least one memory device, and a multiplexer configured to select between the first interface channel and the second interface channel.

Abstract: According to one embodiment a semiconductor device is provided. The device includes a first compensator to generate a first compensated signal and a first limiter to control operation of the first compensator. Furthermore, a second compensator to generate a second compensated signal and a second limiter to control operation of the second compensator is provided. An output device is adapted to receive the first compensated signal and the second compensated signal to drive an output.

Abstract: A system for multimodal biometric identification has a first imaging system that detects one or more subjects in a first field of view, including a targeted subject having a first biometric characteristic and a second biometric characteristic; a second imaging system that captures a first image of the first biometric characteristic according to first photons, where the first biometric characteristic is positioned in a second field of view smaller than the first field of view, and the first image includes first data for biometric identification; a third imaging system that captures a second image of the second biometric characteristic according to second photons, where the second biometric characteristic is positioned in a third field of view which is smaller than the first and second fields of view, and the second image includes second data for biometric identification. At least one active illumination source emits the second photons.

Abstract: A multimodal biometric identification system captures and processes images of both the iris and the retina for biometric identification. Another multimodal ocular system captures and processes images of the iris and/or the from both eyes of a subject. Biometrics based on data provided by these systems are more accurate and robust than using biometrics that include data from only the iris or only the retina from a single eye. An exemplary embodiment emits photons to the iris and the retina of both eyes, an iris image sensor that captures an image of the iris when the iris reflects the emitted light, a retina image sensor that captures an image of the retina when the retina reflects the emitted light, and a controller that controls the iris and the retina illumination sources, where the captured image of the iris and the captured image of the retina contain biometric data.

Abstract: The present invention describes a novel method for crosslinking organic semiconductors and conductors by initiating this crosslinking in an autophotosensitised manner. It furthermore describes the production of organic electronic devices through the use of this crosslinking method. The properties of the electronic devices are thereby improved.

Abstract: Retinal blood vessels are detected for biometric identification by: receiving at least one image with retinal data; detecting an area in the image corresponding to a spatial variation in the image; and determining a blood vessel pattern relative in the area. The spatial variation may be determined according to a spatial intensity gradient. The area corresponding to the spatial variation may be defined by a fitted shape. A specific embodiment determines a structural measurement, such as a structural center of mass, in the area, and the blood vessel pattern is determined relative to the structural measurement. The blood vessel pattern may be determined by identifying blood vessel cross sections within the area and linking the blood vessel cross sections to determine blood vessels. Furthermore, each of the blood vessel cross sections may be represented by an N-vector determined by a N-parameter non-linear fitting function or a linear function combination.

Abstract: The present invention describes organic electronic devices in which at least one organic layer off low refractive index is introduced. The light output of the electronic devices is thereby improved.

Abstract: A semiconductor device having composite dielectric layer formed between a silicon substrate and a gate electrode. The composite gate dielectric layer including a layer of silicon oxide, SiOx?2, having a dielectric constant of greater than about 3.9 and about 12 or less, and a complementary dielectric layer for inhibiting the flow of leakage current through the composite dielectric layer.

Abstract: A method and system captures a sequence of images of a biometric wherein the images include a common reference. The system aligns the images represented by the image data with respect to the common reference. Thereafter, the system analyzes an attribute of the biometric represented in the sequence of images to determine whether the attribute changes in the sequence of images in accordance with a living source.

Abstract: Injection devices, systems and methods are disclosed for injecting two or more medicaments to a patient at a single injection site while preferably minimizing any mixing of the medicaments prior to delivery to the patient. The invention can also be used to sequentially deliver the medicaments to the patient in a repetitive manner. For example, the injection apparatus can sequentially provide a first medicament and then a second medicament to the patient during a first injection procedure. During a second injection procedure, the injection apparatus can again sequentially provide the first medicament and the second medicament to the patient either at the injection site of the first injection procedure or at a different injection site. Multi-lumen manifolds are disclosed for coupling to conventional drug ampoules, to permit the user to sequentially delivery different medicaments via a single skin penetration. Systems including multiple drug reservoirs and filling adaptors are also disclosed.

Abstract: Injection devices, systems and methods are disclosed for injecting two or more medicaments to a patient at a single injection site while preferably minimizing any mixing of the medicaments prior to delivery to the patient. The invention can also be used to sequentially deliver the medicaments to the patient in a repetitive manner. For example, the injection apparatus can sequentially provide a first medicament and then a second medicament to the patient during a first injection procedure. During a second injection procedure, the injection apparatus can again sequentially provide the first medicament and the second medicament to the patient either at the injection site of the first injection procedure or at a different injection site. Multi-lumen manifolds are disclosed for coupling to conventional drug ampoules, to permit the user to sequentially delivery different medicaments via a single skin penetration and to reduce losses associated with usage.