Patents by Inventor David N. Breslauer

David N. Breslauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180282380
    Abstract: The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include expression constructs, recombinant vectors, and recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to recombinant secretion signals that comprise the leader peptide of the ?-mating factor (?MF) of Saccharomyces cerevisiae and a non-?MF signal peptide.
    Type: Application
    Filed: March 13, 2018
    Publication date: October 4, 2018
    Inventors: Joshua Kittleson, Thomas Stevens, Rena Hill, Carlos Gustavo Pesce, David N. Breslauer, Daniel M. Widmaier
  • Publication number: 20180282937
    Abstract: The present disclosure relates generally to pre-treating textiles and methods of preparing textiles in a pre-treated state. Specifically, the present disclosure relates to pre-treating textiles comprising recombinant protein fibers.
    Type: Application
    Filed: March 13, 2018
    Publication date: October 4, 2018
    Inventors: Jamie McAusland Bainbridge, Lindsay Wray, Mitchell Heinrich, Joshua Kittleson, David N. Breslauer
  • Publication number: 20180273693
    Abstract: The present disclosure provides methods and compositions for directed to synthetic block copolymer proteins, expression constructs for their secretion, recombinant microorganisms for their production, and synthetic fibers (including advantageously, microfibers) comprising these proteins that recapitulate many properties of natural silk. The recombinant microorganisms can be used for the commercial production of silk-like fibers.
    Type: Application
    Filed: April 4, 2018
    Publication date: September 27, 2018
    Inventors: Daniel M. Widmaier, David N. Breslauer, Joshua Kittleson, Brendan Turner, Lindsay Wray
  • Patent number: 10035886
    Abstract: The present disclosure provides methods and compositions for directed to synthetic block copolymer proteins, expression constructs for their secretion, recombinant microorganisms for their production, and synthetic fibers (including advantageously, microfibers) comprising these proteins that recapitulate many properties of natural silk. The recombinant microorganisms can be used for the commercial production of silk-like fibers.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: July 31, 2018
    Assignee: Bolt Threads, Inc.
    Inventors: Daniel M. Widmaier, David N. Breslauer, Joshua Kittleson, Brendan Turner, Lindsay Wray
  • Patent number: 9963554
    Abstract: The present disclosure provides methods and compositions for directed to synthetic block copolymer proteins, expression constructs for their secretion, recombinant microorganisms for their production, and synthetic fibers (including advantageously, microfibers) comprising these proteins that recapitulate many properties of natural silk. The recombinant microorganisms can be used for the commercial production of silk-like fibers.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: May 8, 2018
    Assignee: Bolt Threads, Inc.
    Inventors: Daniel M. Widmaier, David N. Breslauer, Joshua Kittleson, Brendan Turner, Lindsay Wray
  • Publication number: 20170160533
    Abstract: An imaging system consisting of a cell-phone with camera as the detection part of an optical train which includes other components. Optionally, an illumination system to create controlled contrast in the sample. Uses include but are not limited to disease diagnosis, symptom analysis, and post-procedure monitoring, and other applications to humans, animals, and plants.
    Type: Application
    Filed: November 9, 2016
    Publication date: June 8, 2017
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel Fletcher, Wendy Hansen, Neil Switz, David N. Breslauer, Erik Douglas, Robi Maamari, Wilbur Lam, Jesse Dill
  • Publication number: 20170088675
    Abstract: The present disclosure provides methods and compositions for directed to synthetic block copolymer proteins, expression constructs for their secretion, recombinant microorganisms for their production, and synthetic fibers (including advantageously, microfibers) comprising these proteins that recapitulate many properties of natural silk. The recombinant microorganisms can be used for the commercial production of silk-like fibers.
    Type: Application
    Filed: October 4, 2016
    Publication date: March 30, 2017
    Inventors: Daniel M. Widmaier, David N. Breslauer, Joshua Kittleson, Brendan Turner, Lindsay Wray
  • Patent number: 9523845
    Abstract: An imaging system consisting of a cell-phone with camera as the detection part of an optical train which includes other components. Optionally, an illumination system to create controlled contrast in the sample. Uses include but are not limited to disease diagnosis, symptom analysis, and post-procedure monitoring, and other applications to humans, animals, and plants.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: December 20, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel Fletcher, Wendy Hansen, Neil Switz, David N. Breslauer, Erik Douglas, Robi Maamari, Wilbur Lam, Jesse Dill
  • Publication number: 20160222174
    Abstract: The present disclosure provides methods and compositions for directed to synthetic block copolymer proteins, expression constructs for their secretion, recombinant microorganisms for their production, and synthetic fibers (including advantageously, microfibers) comprising these proteins that recapitulate many properties of natural silk. The recombinant microorganisms can be used for the commercial production of silk-like fibers.
    Type: Application
    Filed: March 17, 2016
    Publication date: August 4, 2016
    Inventors: Daniel M. Widmaier, David N. Breslauer, Joshua Kittleson, Brendan Turner, Lindsay Wray
  • Publication number: 20160054555
    Abstract: An imaging system consisting of a cell-phone with camera as the detection part of an optical train which includes other components. Optionally, an illumination system to create controlled contrast in the sample. Uses include but are not limited to disease diagnosis, symptom analysis, and post-procedure monitoring, and other applications to humans, animals, and plants.
    Type: Application
    Filed: August 28, 2015
    Publication date: February 25, 2016
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel Fletcher, Wendy Hansen, Neil Switz, David N. Breslauer, Erik Douglas, Robi Maamari, Wilbur Lam, Jesse Dill
  • Patent number: 9154594
    Abstract: An imaging system consisting of a cell-phone with camera as the detection part of an optical train which includes other components. Optionally, an illumination system to create controlled contrast in the sample. Uses include but are not limited to disease diagnosis, symptom analysis, and post-procedure monitoring, and other applications to humans, animals, and plants.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: October 6, 2015
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel Fletcher, Wendy Hansen, Neil Switz, David N. Breslauer, Erik Douglas, Robi Maamari, Wilbur Lam, Jesse Dill
  • Publication number: 20150005032
    Abstract: An imaging system consisting of a cell-phone with camera as the detection part of an optical train which includes other components. Optionally, an illumination system to create controlled contrast in the sample. Uses include but are not limited to disease diagnosis, symptom analysis, and post-procedure monitoring, and other applications to humans, animals, and plants.
    Type: Application
    Filed: June 11, 2014
    Publication date: January 1, 2015
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel Fletcher, Wendy Hansen, Neil Switz, David N. Breslauer, Erik Douglas, Robi Maamari, Wilbur Lam, Jesse Dill
  • Patent number: 8786695
    Abstract: An imaging system consisting of a cell-phone with camera as the detection part of an optical train which includes other components. Optionally, an illumination system to create controlled contrast in the sample. Uses include but are not limited to disease diagnosis, symptom analysis, and post-procedure monitoring, and other applications to humans, animals, and plants.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: July 22, 2014
    Assignee: The Regents of the University of California
    Inventors: Daniel Fletcher, Wendy Hansen, Neil Switz, David N. Breslauer, Erik Douglas, Robi Maamari, Wilbur Lam, Jesse Dill
  • Publication number: 20140120982
    Abstract: An imaging system consisting of a cell-phone with camera as the detection part of an optical train which includes other components. Optionally, an illumination system to create controlled contrast in the sample. Uses include but are not limited to disease diagnosis, symptom analysis, and post-procedure monitoring, and other applications to humans, animals, and plants.
    Type: Application
    Filed: January 8, 2014
    Publication date: May 1, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel Fletcher, Wendy Hansen, Neil Switz, David N. Breslauer, Erik Douglas, Robi Maamari, Wilbur Lam, Jesse Dill
  • Publication number: 20100013115
    Abstract: A method and apparatus for forming materials such as fiber and elongated shapes, including: a tapered flow channel; supply channels for the addition and removal of agents into the tapered flow channel; and a fiber outlet at the distal end of the tapering flow channel.
    Type: Application
    Filed: June 5, 2007
    Publication date: January 21, 2010
    Inventors: David N. Breslauer, Luke P. Lee