Patents by Inventor David N. Finegold

David N. Finegold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPUTATIONAL FILTERING OF METHYLATED SEQUENCE DATA FOR PREDICTIVE MODELING
    Publication number: 20220262462
    Abstract: Computational techniques are disclosed for using methylation profiles to classify the medication condition of a person. Initial sequence data is obtained containing sequences of an initial set of nucleic acids from a biological sample of a person. The initial sequence data is filtered to generate filtered sequence data that describes sequences of a filtered subset of nucleic acids from the biological sample. A methylation profile is determined for the filtered subset of nucleic acids from the biological sample. The methylation profile can be processed to determine a likelihood that the person has the specified medical condition. The system outputs an indication of the likelihood that the person has the specified medical condition.
    Type: Application
    Filed: April 10, 2020
    Publication date: August 18, 2022
    Inventors: David Gerard Peters, Tianjiao Chu, Lisa Ann Pan, David N. Finegold
  • COMPUTATIONAL FILTERING OF METHYLATED SEQUENCE DATA FOR PREDICTIVE MODELING
    Publication number: 20200327959
    Abstract: Computational techniques are disclosed for using methylation profiles to classify the medication condition of a person. Initial sequence data is obtained containing sequences of an initial set of nucleic acids from a biological sample of a person. The initial sequence data is filtered to generate filtered sequence data that describes sequences of a filtered subset of nucleic acids from the biological sample. A methylation profile is determined for the filtered subset of nucleic acids from the biological sample. The methylation profile can be processed to determine a likelihood that the person has the specified medical condition. The system outputs an indication of the likelihood that the person has the specified medical condition.
    Type: Application
    Filed: April 10, 2020
    Publication date: October 15, 2020
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: David Gerard Peters, Tianjiao Chu, Lisa Ann Pan, David N. Finegold
  • Method of treatment for lymphedema comprising administering a polynucleotide encoding VEGF-D
    Patent number: 8357669
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: January 22, 2013
    Assignees: Vegenics Pty Limited, University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • SCREENING AND THERAPY FOR LYMPHATIC DISORDERS INVOLVING THE FLT4 RECEPTOR TYROSINE KINASE (VEGFR-3)
    Publication number: 20120010276
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: September 23, 2011
    Publication date: January 12, 2012
    Applicants: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, VEGENICS PTY LTD
    Inventors: ROBERT E. FERRELL, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Screening and Therapy for Lymphatic Disorders Involving the FLT4 Receptor Tyrosine Kinase (VEGFR-3)
    Publication number: 20110065636
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: November 6, 2010
    Publication date: March 17, 2011
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Method of treating lymphedema comprising administering VEGF-D
    Patent number: 7829536
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: November 9, 2010
    Assignees: Vegenics Limited, University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • SCREENING AND THERAPY FOR LYMPHATIC DISORDERS INVOLVING THE FLT4 RECEPTOR TYROSINE KINASE (VEGFR-3)
    Publication number: 20090191166
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: February 5, 2009
    Publication date: July 30, 2009
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Screening for lymphatic disorders involving the FLT4 receptor tyrosine kinase (VEGFR-3)
    Patent number: 6764820
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Grant
    Filed: August 16, 1999
    Date of Patent: July 20, 2004
    Assignees: Ludwig Institute for Cancer Research, Licentia, Ltd., University of Pittsburgh-of the Commonwealth System of Higher Education
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Screening and therapy for lymphatic disorders involving the FLT4 receptor tyrosine kinase (VEGFR-3)
    Publication number: 20040063656
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: September 12, 2003
    Publication date: April 1, 2004
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • SCREENING AND THERAPY FOR LYMPHATIC DISORDERS INVOLVING THE FLT4 RECEPTOR TYROSINE KINASE (VEGFR-3)
    Publication number: 20030026759
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: August 16, 1999
    Publication date: February 6, 2003
    Inventors: ROBERT E. FERRELL, KARI ALITALO, DAVID N. FINEGOLD, MARIKA KARKKAINEN