Patents by Inventor David N. Paglia

David N. Paglia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180318344
    Abstract: A method for repairing an injury of cartilage in a patient by local administration of a zinc or manganese agent or use of an implantable device for delivery of an a zinc or manganese agent. Implantable devices containing a zinc or manganese agent and methods of making these implantable devices are also disclosed.
    Type: Application
    Filed: April 2, 2018
    Publication date: November 8, 2018
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Aaron Wey, Joseph Benevenia, Virak Tan
  • Patent number: 9999636
    Abstract: Methods of promoting bone healing or regeneration by locally administering insulin mimetic agents to patients in need thereof and new uses of insulin-mimetic compounds for accelerating bone-healing processes are disclosed. Bone injury treatment and void filler devices, products and kit suitable for local administration of insulin-mimetic, agents or compositions thereof to patients in need of such treatment are also disclosed.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: June 19, 2018
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Joseph Benevenia, Aaron Wey, Sangeeta Subramanian, John Koerner, Paul Chirichella, Michael J. Vives
  • Patent number: 9931348
    Abstract: A method for repairing an injury of cartilage in a patient by local administration of an organovanadium agent or use of an implantable device for delivery of an organovanadium agent. Implantable devices containing an organovanadium agent and methods of making these implantable devices are also disclosed.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: April 3, 2018
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Aaron Wey, Joseph Benevenia, Virak Tan
  • Patent number: 9730946
    Abstract: This invention provides a method of promoting bone healing by locally administering a vanadium-based insulin mimetic agent to a patient in need thereof. The invention also provides a new use of insulin-mimetic vanadium compounds for manufacture of medicaments for accelerating bone-healing processes. In addition, the invention also encompasses a bone injury treatment kit suitable for localized administration of insulin-mimetic vanadium compounds or compositions thereof to a patient in need of such treatment.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: August 15, 2017
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Eric Breitbart, Joseph Benevenia
  • Publication number: 20160151416
    Abstract: Methods of promoting bone healing or regeneration by locally administering insulin mimetic agents to patients in need thereof and new uses of insulin-mimetic compounds for accelerating bone-healing processes are disclosed. Bone injury treatment and void filler devices, products and kit suitable for local administration of insulin-mimetic, agents or compositions thereof to patients in need of such treatment are also disclosed.
    Type: Application
    Filed: January 29, 2016
    Publication date: June 2, 2016
    Applicants: Rutgers, The State University of New Jersey, Rutgers, The State University of New Jersey
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Joseph Benevenia, Aaron Wey, Sangeeta Subramanian, John Koerner, Paul Chirichella, Michael J. Vives
  • Patent number: 9265794
    Abstract: Methods of promoting bone healing or regeneration by locally administering insulin mimetic agents to patients in need thereof and new uses of insulin-mimetic compounds for accelerating bone-healing processes are disclosed. Bone injury treatment and void filler devices, products and kit suitable for local administration of insulin-mimetic agents or compositions thereof to patients in need of such treatment are also disclosed.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: February 23, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Joseph Benevenia, Aaron Wey, Sangeeta Subramanian, John D. Koerner, Paul Chirichella, Michael J. Vives
  • Publication number: 20150314047
    Abstract: The present invention discloses boron composite surface coatings, application of these coatings onto implantable devices, and use of the implantable devices for accelerating osseous healing. The implantable devices have wide applications, including but not limited to treating bone fracture, bone trauma, arthrodesis, and other bone deficit conditions, as well as bone injuries incurred in military and sports activities.
    Type: Application
    Filed: May 1, 2014
    Publication date: November 5, 2015
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Eric Breitbart, Joseph Benevenia
  • Patent number: 9144633
    Abstract: The present invention discloses vanadium-based insulin-mimetic agent composite coatings, application of these coatings onto implantable devices, and use of the implantable devices for accelerating osseous healing. The invention also encompasses methods of manufacturing implantable devices coated with vanadium-based insulin-mimetic agent composite coatings and the implantable devices so manufactured. The implantable devices have wide applications, including but not limited to treating bone fracture, bone trauma, arthrodesis, and other bone deficit conditions, as well as bone injuries incurred in military and sports activities.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: September 29, 2015
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James Patrick O'Connor, Eric Breitbart, Joseph Benevenia
  • Publication number: 20150099804
    Abstract: This invention provides a method of promoting bone healing by locally administering a vanadium-based insulin mimetic agent to a patient in need thereof. The invention also provides a new use of insulin-mimetic vanadium compounds for manufacture of medicaments for accelerating bone-healing processes. In addition, the invention also encompasses a bone injury treatment kit suitable for localized administration of insulin-mimetic vanadium compounds or compositions thereof to a patient in need of such treatment.
    Type: Application
    Filed: December 10, 2014
    Publication date: April 9, 2015
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Eric Breitbart, Joseph Benevenia
  • Publication number: 20150030653
    Abstract: A method for repairing an injury of cartilage in a patient by local administration of an organovanadium agent or use of an implantable device for delivery of an organovanadium agent. Implantable devices containing an organovanadium agent and methods of making these implantable devices are also disclosed.
    Type: Application
    Filed: July 6, 2012
    Publication date: January 29, 2015
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Aaron Wey, Joseph Benevenia, Virak Tan
  • Publication number: 20150010499
    Abstract: Methods of promoting bone healing or regeneration by locally administering insulin mimetic agents to patients in need thereof and new uses of insulin-mimetic compounds for accelerating bone-healing processes are disclosed. Bone injury treatment and void filler devices, products and kit suitable for local administration of insulin-mimetic agents or compositions thereof to patients in need of such treatment are also disclosed.
    Type: Application
    Filed: August 26, 2014
    Publication date: January 8, 2015
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Joseph Benevenia, Aaron Wey, Sangeeta Subramanian, John D. Koerner
  • Publication number: 20140322292
    Abstract: Methods of promoting bone healing or regeneration by locally administering insulin mimetic agents to patients in need thereof and new uses of insulin-mimetic compounds for accelerating bone-healing processes are disclosed. Bone injury treatment and void filler devices, products and kit suitable for local administration of insulin-mimetic agents or compositions thereof to patients in need of such treatment are also disclosed.
    Type: Application
    Filed: November 29, 2012
    Publication date: October 30, 2014
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Sheldon S. Lin, David N. Paglia, James P. O'Connor, Joseph Benevenia, Aaron Wey, Sangeeta Subramanian, John D. Koerner
  • Publication number: 20140044768
    Abstract: The present invention discloses vanadium-based insulin-mimetic agent composite coatings, application of these coatings onto implantable devices, and use of the implantable devices for accelerating osseous healing. The invention also encompasses methods of manufacturing implantable devices coated with vanadium-based insulin-mimetic agent composite coatings and the implantable devices so manufactured. The implantable devices have wide applications, including but not limited to treating bone fracture, bone trauma, arthrodesis, and other bone deficit conditions, as well as bone injuries incurred in military and sports activities.
    Type: Application
    Filed: December 9, 2011
    Publication date: February 13, 2014
    Applicant: University of Medicine and Dentistry of New Jersey
    Inventors: Sheldon S. Lin, David N. Paglia, Eric Breitbart, Joseph Benevenia