Patents by Inventor David N. Ridge

David N. Ridge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel intermediates and an improved process for producing the compound (3.beta.,5.alpha.)-3-hydroxycholest-8(14)-en-15-one
    Patent number: 4900477
    Abstract: An improved process for the large scale production of the compound (3.beta.,5.alpha.)-3-hydroxycholest-8(14)-en-15-one is described and two new compounds which have utility as intermediates in synthetic routes to the subject compound are disclosed.
    Type: Grant
    Filed: March 28, 1988
    Date of Patent: February 13, 1990
    Assignee: American Cyanamid Company
    Inventors: William D. Dean, Robert F. R. Church, David N. Ridge
  • Substituted 1H-1,2,4-triazoles
    Patent number: 4329463
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted 1-phenyl-1H-1,2,4-triazoles and/or the pharmacologically acceptable acid-addition salts thereof.
    Type: Grant
    Filed: December 2, 1980
    Date of Patent: May 11, 1982
    Assignee: American Cyanamid Company
    Inventors: Stanley A. Lang, Jr., Yang-i Lin, David N. Ridge
  • Substituted phenyl esters of isoxazolecarboxylic acids
    Patent number: 4284785
    Abstract: Isoxazolecarboxylic acid phenyl esters which are intermediates for the preparation of anti-inflammatory agents.
    Type: Grant
    Filed: December 19, 1979
    Date of Patent: August 18, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • 2-Benzoyl-3-dimethylamino-2-alkenonitriles
    Patent number: 4259256
    Abstract: This disclosure describes novel substituted 2-benzoyl-3-alkoxy-2-alkenonitriles and substituted 2-benzoyl-3-amino-2-alkenonitriles which are useful as intermediates for the preparation of certain substituted cis-2-benzoyl-3-hydroxy-2-alkenonitriles which possess anti-inflammatory activity.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: March 31, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Substituted 1H-1,2,4-triazoles
    Patent number: 4259504
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted 1-phenyl-1H-1,2,4-triazoles and/or the pharmacologically acceptable acid-addition salts thereof.
    Type: Grant
    Filed: August 27, 1979
    Date of Patent: March 31, 1981
    Assignee: American Cyanamid Company
    Inventors: Stanley A. Lang, Jr., Yang-I Lin, David N. Ridge
  • Substituted phenyl alkylidene acetoacetonitriles
    Patent number: 4254048
    Abstract: Substituted-phenyl alkylidene acetoacetonitriles which are useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: March 3, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Substituted phenyl-2-cyano-2-thioalkenoic acid esters
    Patent number: 4254047
    Abstract: Substituted phenyl-2-cyano-2-thioalkenoic acid esters which are useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: March 3, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Substituted phenyl-2-cyano-2-alkenoic acid esters
    Patent number: 4254049
    Abstract: Substituted phenyl-2-cyano-2-alkenoic acid esters which are useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: March 3, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • .beta.-Oxo-3-thiophenepropionitrile and .beta.-amino-2-(3)-thiopheneacrylonitriles
    Patent number: 4241077
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said compositions of matter being .beta.-oxo-3-thiophenepropionitrile, .beta.-amino-2-thiopheneacrylonitrile, and/or .beta.-amino-3-thiopheneacrylonitrile.
    Type: Grant
    Filed: August 8, 1979
    Date of Patent: December 23, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, David N. Ridge
  • Thiophenepropionitriles
    Patent number: 4197310
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted cis-2-[2(or 3)-thenoyl]-3-hydroxy-2-alkenenitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: April 30, 1979
    Date of Patent: April 8, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • .beta.-oxo-3-thiophene propionitrile and .beta.-amino-2-(3)-thiophene acrylonitriles
    Patent number: 4189436
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said compositions of matter being .beta.-oxo-3-thiophenepropionitrile, .beta.-amino-2-thiopheneacrylonitrile, and/or .beta.-amino-3-thiopheneacrylonitrile.
    Type: Grant
    Filed: August 24, 1978
    Date of Patent: February 19, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, David N. Ridge
  • 2-Benzoyl-3-alkoxy-2-alkenonitriles
    Patent number: 4181677
    Abstract: This disclosure describes novel substituted 2-benzoyl-3-alkoxy-2-alkenonitriles and substituted 2-benzoyl-3-amino-2-alkenonitriles which are useful as intermediates for the preparation of certain substituted cis-2-benzoyl-3-hydroxy-2-alkenonitriles which possess anti-inflammatory activity.
    Type: Grant
    Filed: December 13, 1978
    Date of Patent: January 1, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Cis-2-benzoyl-3-hydroxy-2-alkenonitriles as anti-inflammatory agents
    Patent number: 4173650
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted cis-2-benozyl-3-hydroxy-2-alkenonitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: November 3, 1978
    Date of Patent: November 6, 1979
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Compositions containing cis-2-benzoyl-3-hydroxy-crotononitrile used to treat inflammation and joint deterioration
    Patent number: 4170656
    Abstract: This disclosure describes compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease, and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said composition of matter being certain cis-2-benzoyl-3-hydroxy-2-alkenonitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: March 31, 1978
    Date of Patent: October 9, 1979
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge