Abstract: Systems and methods for automating the production of dental aligners is disclosed. In some embodiments the systems and methods include a three-dimensional printer in communication with one or more computer and one or more computer programs. The system and method configured to permit persons to automatically scan and upload a pre-existing digital scan, x-ray, physical mold or other impression of a person's teeth to the three-dimensional printer for direct real-time printing of custom dental aligners. In some embodiments, the system and method also includes an intraoral scanner configured to permit persons to take and receive a real-time digital scan of their teeth and receive a real-time custom dental aligner, on the same day and from the same integrated system, method, machine, kiosk and location.