Patents by Inventor David Nelles

David Nelles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Directed editing of cellular RNA via nuclear delivery of CRISPR/Cas9
    Patent number: 12163148
    Abstract: Disclosed herein is a technology to perform programmable RNA editing at single-nucleotide resolution using RNA-targeting CRISPR/Cas9. This approach, which Applicants have termed “Cas9-directed RNA editing” or “CREDIT,” provides a means to reversibly alter genetic information in a temporal manner, unlike traditional CRISPR/Cas9 driven genomic engineering which relies on permanently altering DNA sequence.
    Type: Grant
    Filed: July 11, 2022
    Date of Patent: December 10, 2024
    Assignee: The Regents of the University of California
    Inventors: Eugene Yeo, Kristopher Brannan, Ryan Marina, David Nelles
  • DIRECTED EDITING OF CELLULAR RNA VIA NUCLEAR DELIVERY OF CRISPR/CAS9
    Publication number: 20230053915
    Abstract: Disclosed herein is a technology to perform programmable RNA editing at single-nucleotide resolution using RNA-targeting CRISPR/Cas9. This approach, which Applicants have termed “Cas9-directed RNA editing” or “CREDIT,” provides a means to reversibly alter genetic information in a temporal manner, unlike traditional CRISPR/Cas9 driven genomic engineering which relies on permanently altering DNA sequence.
    Type: Application
    Filed: July 11, 2022
    Publication date: February 23, 2023
    Inventors: Eugene Yeo, Kristopher Brannan, Ryan Marina, David Nelles
  • Directed editing of cellular RNA via nuclear delivery of CRISPR/CAS9
    Patent number: 11453891
    Abstract: Disclosed herein is a technology to perform programmable RNA editing at single-nucleotide resolution using RNA-targeting CRISPR/Cas9. This approach, which Applicants have termed “Cas9-directed RNA editing” or “CREDIT,” provides a means to reversibly alter genetic information in a temporal manner, unlike traditional CRISPR/Cas9 driven genomic engineering which relies on permanently altering DNA sequence.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: September 27, 2022
    Assignee: The Regents of the University of California
    Inventors: Eugene Yeo, Kristopher Brannan, Ryan Marina, David Nelles
  • DIRECTED EDITING OF CELLULAR RNA VIA NUCLEAR DELIVERY OF CRISPR/CAS9
    Publication number: 20180334685
    Abstract: Disclosed herein is a technology to perform programmable RNA editing at single-nucleotide resolution using RNA-targeting CRISPR/Cas9. This approach, which Applicants have termed “Cas9-directed RNA editing” or “CREDIT,” provides a means to reversibly alter genetic information in a temporal manner, unlike traditional CRISPR/Cas9 driven genomic engineering which relies on permanently altering DNA sequence.
    Type: Application
    Filed: May 9, 2018
    Publication date: November 22, 2018
    Inventors: Eugene Yeo, Kristopher Brannan, Ryan Marina, David Nelles
  • Method for visualization of optical network topology
    Publication number: 20060129939
    Abstract: A method for the simultaneous graphical display of paths of optical wavelength channels in a telecommunications network together with one or more channel attributes is provided. The graphical display of the network also shows the direction of data flow transported by the channels. An audible or visual alarm for an error condition for a channel attribute on a link in the network can be produced if requires. The operator can also obtain detailed information on a channel by positioning the mouse over a channel.
    Type: Application
    Filed: February 7, 2006
    Publication date: June 15, 2006
    Inventors: David Nelles, Daniel Adamski, Paul Obeda, Victoria Donnelly