Abstract: Example apparatus disclosed herein are to cause meter software to be provided to a compute device, the meter software executable by the compute device to monitor use of the compute device associated with presentation of media. Disclosed example solutions are also to collect demographic data of a user associated with the compute device, the demographic data collected from a source different from the compute device. Disclosed example solutions are further to obtain meter data from the compute device, the meter data generated by the meter software, and associate the meter data with the demographic data.

Abstract: A device and method for forming NO-containing gas flow to treat a biological object is disclosed. The device may include an anode, a cathode, an interelectrode area between the cathode and the anode, an NO-containing gas flow outlet channel leading from the interelectrode area to a nozzle for directing and releasing the NO-containing gas flow from the device and a mechanism to adjust a relative position between the anode and the cathode to produce varying concentrations of NO. In addition, the device may include one or more features for interconnecting the various components to ensure proper and consistent assembly of the device.

Abstract: A significant interest lies in compositions that hinder the metastatic process. This process, along with recurrence, is associated with a subset of highly invasive tumorigenic cells expressing CD44. Described herein are CD44-modulating peptide compositions for combination therapy as well as method of use thereof to treat or ameliorate tumors or cancers like ovarian cancer, endometrial cancer, or triple-negative breast cancer.

Abstract: Apparatuses and systems are provided which include a drug waste depository apparatus with a housing having a waste input port and a chamber, wherein the chamber comprises a waste inlet coupled to the waste input port and a waste outlet. The housing includes an interior space for receiving a removable module that is configured to analyze, sequester, and/or adulterate one or more drugs. The system is configured such that the waste outlet of the chamber may be coupled to an inlet of a received module and is further configured such that the waste outlet of the chamber may be closed when the interior space is void of a module. In addition, a drug waste depository apparatus is provided which is programmed to selectively route a drug from a first chamber to a second chamber of the apparatus based on information received at an electronic user interface of the apparatus.

Abstract: A medical connector for use in a fluid pathway includes a housing configured to permit fluid flow between a first medical device and a second device or location. The medical connector includes a valve member configured to be positioned at least partially within the housing. The valve member is configured to receive the first medical device. The valve member can be moved into a second state. The connector can be adapted for use with a catheter assembly.

Abstract: The current invention pertains to devices for counting and sizing particles suspended in a stream of fluid flowing in a predominant flow direction. Such devices comprise a fluid stream forming system having a directional element arranged to form the stream of fluid flowing in predetermined direction of fluid flow; a laser beam forming optical system including at least one source of laser light having at least one wavelength between 200 nm and 1000 nm, a profiling optical subsystem, having at least one collimator lens and at least one convergent lens, positioned to arrange the laser light in a laser beam along a laser beam axis directed substantially to illuminate a prearranged scattering volume of the stream of fluid, and at least one laser beam dump. Also, the device includes a wide-angle detecting subsystem and wide-angle back-reflecting subsystem.

Abstract: Techniques discussed herein relate to updating an edge device (e.g., a computing device distinct from and operating remotely with respect to a data center). The edge device can execute a first operating system (OS). A manifest specifying files of a second OS to be provisioned to the edge device may be obtained. The manifest may further specify a set of services to be provisioned at the edge device. One or more data files corresponding to a difference between a first set of data files associated with the first OS and a second set of data files associated with the second OS may be identified. A snapshot of the first OS may be generated, modified, and stored in memory of the edge device to configure the edge device with the second OS. The booting order of the edge device may be modified to boot utilizing the second OS.

Abstract: Embodiments of an artificial meniscus are disclosed herein. An artificial meniscus includes at least one circumferential fiber bundle and the at least one non-circumferential fiber bundle embedded in a polymer material. The non-circumferential fiber bundles are fully encapsulated within the polymer material, and the circumferential fiber bundles extend out of anterior and posterior horns of the artificial meniscus to terminate in ends that are configured for fixation to bone. Methods of making and implanting artificial menisci are also disclosed herein. The methods of making include, but are not limited to, stepwise molding, layering, and curing of polymer material around the circumferential and non-circumferential fiber bundles. The methods of implanting include threading ends of the circumferential fiber bundles through first and second bone tunnels, then immobilizing the ends of the circumferential fiber bundles with respect to the bone of the subject.

Abstract: A fluid transfer device can include a first attachment portion configured to engage a first port of a source container and a second attachment portion configured to engage a second port of an intermediate container. The first attachment portion can include a first projection defining a first fluid passage and the second attachment portion can include a second projection defining a second fluid passage. The fluid transfer device can further include a selector portion for selectively transitioning the fluid transfer device from a first configuration in which a flow path between the first and second fluid passages is closed to a second configuration in which the flow path between the first and second fluid passages is open. The fluid transfer device can further include a limiter configured to inhibit the selector portion from selectively transitioning the fluid transfer device from the first configuration to the second configuration.

Abstract: A stator for an electric motor is described. An example stator includes a stator core having teeth that are radially arranged about a common central axis of the stator and located in a spaced apart manner from one another. Each tooth has an inward portion and an outward portion. The example stator further includes an electrically transmissive coil of wire that is wound contiguously upon the inward portions of at least a subset of teeth from the plurality of teeth. The stator also includes wedge members that are radially arranged about the common central axis and located intermittently with the plurality of teeth such that each wedge member abuts with the outward portions of adjacently located teeth.

Abstract: Air cleaner assemblies, components therefor, and features thereof are described. Also described are methods of assembly and use. In depicted examples, the air cleaner assemblies and components optionally use advantageous housing seal features. Methods of assembly and use are described.

Abstract: A medical connector for use in a fluid pathway. A valve member with sealing rings helps preclude undesired accumulation of fluid within the connector. A branched connector includes a fluid diverter extending away from a port of the branched connector. The fluid diverter is configured to divert fluid flowing through the branched connector and into a medical connector attached thereto, flushing a distal portion of the medical connector.

Abstract: An onboard communication network of a vehicle is monitored to detect a plurality of available messages that include respective cipher-based message authentication codes (CMAC) and that were identified as eligible messages based on having an information entropy greater than a specified threshold. A first message is selected from the plurality of available messages. The CMAC of the selected message is input into a random number generator that outputs a random number seeded by the CMAC of the selected message. Then the random number is provided.

Abstract: A breakaway medical connector can include a housing with engagement features that interface with corresponding engagement features on a breakaway member so that the breakaway is attached to the housing. A second connector can couple to the breakaway member to provide a fluid connection between the first connector and the second connector. If a force above a threshold is applied that pulls the second connector apart from the breakaway connector, the engagement features can be overcome and the breakaway member can detach from the housing. The second connector can detach from the first connector along with the breakaway member. The connector can have a valve that closes the fluid pathway upon the separation of the breakaway member from the housing. In some embodiments, the breakaway member can be reattached to the housing, such as to reestablish fluid communication between the breakaway medical connector and the second medical connector.

Abstract: Methods and CD44-modulating peptide compositions for treating or ameliorating ascites, for treating or ameliorating a tumor or cancer, wherein the compositions feature binding moieties such as monoclonal antibodies or fragments thereof specific for CD44 that inhibit CD44 activity, or CD44-modulating peptides that bind to and modulate activity of CD44, optionally featuring a pharmaceutically acceptable carrier. The binding moieties herein may be used with a secondary therapy. In some embodiments, the monoclonal antibody or fragment thereof binds to at least a portion of the cryptic region of CD44.

Abstract: A stator for an electric motor is described. An example stator includes a stator core having teeth that are radially arranged about a common central axis of the stator and located in a spaced apart manner from one another. Each tooth has an inward portion and an outward portion. The example stator further includes an electrically transmissive coil of wire that is wound contiguously upon the inward portions of at least a subset of teeth from the plurality of teeth. The stator also includes wedge members that are radially arranged about the common central axis and located intermittently with the plurality of teeth such that each wedge member abuts with the outward portions of adjacently located teeth.

Abstract: A computer includes a processor and a memory, and the memory stores instructions executable by the processor to receive a plurality of first message patterns; receive a plurality of second message patterns; determine a set of differences between the first message patterns and the second message patterns; for at least one of the differences, determine a respective resolution in favor of either the first message patterns or the second message patterns; and generate a plurality of third message patterns. The message patterns define messaging between electronic control units on board a vehicle. The message patterns include values for attributes assigned to the respective message patterns. The third message patterns include the at least one resolution and commonalities between the first message patterns and the second message patterns.

Abstract: The present invention relates to methods of treatment for cancer using SPL-108 polypeptide (also known as A6 peptide or A6, a CD44 modulating peptide; FIG. 1; SEQ ID NO:1) based on the TP53 status of the cancer. In particular, this invention relates to such methods of treatment by using TP53 mutational status to guide the administration of an SPL-108 polypeptide or a variant thereof alone or in combination with a standard-of-care treatment for patients with cancer. TP53 mutational status is used to select patients that may or may not respond to SPL-108 polypeptide or a variant thereof; specific mutations TP53 predict the response of patients including progressive disease, stable disease, and/or partial/complete response to SPL-108. Such methods of the present invention are used to treat cancer to alleviate and/or prevent symptoms of cancer, and/or to avoid side effects commonly associated with treating cancer.

Abstract: A fluid transfer device can include a first attachment portion configured to engage a first port of a source container and a second attachment portion configured to engage a second port of an intermediate container. The first attachment portion can include a first projection defining a first fluid passage and the second attachment portion can include a second projection defining a second fluid passage. The fluid transfer device can further include a selector portion for selectively transitioning the fluid transfer device from a first configuration in which a flow path between the first and second fluid passages is closed to a second configuration in which the flow path between the first and second fluid passages is open. The fluid transfer device can further include a limiter configured to inhibit the selector portion from selectively transitioning the fluid transfer device from the first configuration to the second configuration.