Abstract: The present disclosure provides methods for capturing recombinant collagen 7 from cell culture and methods of purifying recombinant collagen 7. Also provided are compositions comprising purified recombinant collagen 7 that may be used for administration to humans.

Abstract: The present invention relates generally to the field of recombinant fatty acid synthesis, particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular, the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome, such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ.

Abstract: Implementations are described of a computing device that migrates data and software applications from a first computing device to a second computing device, in order to preserve data and other application-related customizations.

Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desatorase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.

Abstract: In some embodiments, a blood flow sensor device such as a non-invasive cardiac arrest monitor (NICAM) that uses ultrasound to detect blood flow is used to monitor blood flow during cardiopulmonary resuscitation. One or more gating signal generation devices transmit gating signals to a blood flow monitoring computing device. The blood flow monitoring computing device uses the gating signals to determine time periods during which blood flow information generated by the blood flow sensor device is most likely to be accurate. The blood flow monitoring computing device measures blood flow during the time periods. In some embodiments, the blood flow monitoring computing device presents the measured blood flow to a user. In some embodiments, the blood flow monitoring computing device transmits a command to a chest compression device based on the measured blood flow.

Abstract: This invention is directed to compositions, methods and kits for ameliorating or reducing pathogenesis of a disease by administering to a subject a serotonin receptor agonist.

Abstract: A coated glazing comprising at least the following layers in sequence: a transparent glass substrate, a layer based on an oxide of a metal and/or a layer based on an oxide of a metalloid, and a further layer, wherein either said layer based on an oxide of a metal or said layer based on an oxide of a metalloid is adjacent said transparent glass substrate, wherein said layer that is adjacent said transparent glass substrate comprises a surface that, prior to a coating of said surface, has an arithmetical mean height of the surface value, Sa, of at least 4.0 nm when tested in accordance with ISO 25178-2:2012, and wherein the coated glazing exhibits an average haze value of at least 0.47% when tested in accordance with ASTM D1003-13.

Abstract: A steering system and method for a vehicle having steerable front and rear wheels has rear hydraulic steering device that may be coupled to one or more of the rear wheels. A rear valve assembly may hydraulically control the rear hydraulic steering device to steer the rear wheels based upon a rear steering command from a controller. In a manual steering mode, the controller does not determine a rear steering command for the rear valve assembly such that the rear wheels are freely rotatable. In a rear steering assist mode, the controller determines the rear steering command based upon, at least in part, the manual steering input.

Abstract: A mower-conditioner assembly of a self-propelled windrower includes a frame, a cutting mechanism coupled to the frame for cutting crop, a conditioner rotatably coupled to the frame at a location rearward of the cutting mechanism, and a fluffer assembly rotatably coupled to the frame at a location rearward of the conditioner. The fluffer assembly includes at least an elongated roll and a crop moving element. The conditioner crimps the crop after it is cut, and the fluffer assembly fluffs or moves the crop during operation.

Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desatorase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.

Abstract: Techniques are described for managing creation and/or execution of distributed programs, such as for a group of multiple interrelated programs that are part of a service-oriented architecture or that otherwise interact during execution to provide a desired type of functionality. In at least some situations, the described techniques include performing decentralized choreographed distributed execution of a group of related programs, by using executing supervisor components for some or all such programs to manage execution-related behavior of the programs. The execution-related behavior that is managed by supervisor components for a group of programs may include, for example, managing interactions between the programs, managing run-time dependencies and other relationships between at least some of the programs, managing update strategies for updating some or all of the programs of the group while the group continues to provide functionality (e.g.

Abstract: A spectral imaging device (12) for generating an image (13A) of a sample (10) includes (i) an image sensor (30); (ii) a tunable light source (14) that generates an illumination beam (16) that is directed at the sample (10); (iii) an optical assembly (22) that collects light from the sample (10) and forms an image of the sample (10) on the image sensor (30); and (iv) a control system (32) that controls the tunable light source (14) and the image sensor (30). During a time segment, the control system (32) (i) controls the tunable light source (14) so that the illumination beam (16) has a center wavenumber that is modulated through a first target wavenumber with a first modulation rate; and (ii) controls the image sensor (30) to capture at least one first image at a first frame rate. Further, the first modulation rate is equal to or greater than the first frame rate.

Abstract: An HVAC controller may be programmed using a mobile device having a touch screen display, a wireless port and a controller that is in operative communication with the touch screen display and the wireless port. The controller may establish communication with and download an application program code from the remote download server. The controller may establish a direct wireless connection between the wireless port of the mobile device and the wireless interface of the HVAC controller and execute the application program code, which provides one or more configuration screens on the touch screen display of the mobile device to enable the user to configure the HVAC controller via one or more configuration parameters, and then upload the one or more configuration parameters to the HVAC controller via the direct wireless connection between the wireless port of the mobile device and the wireless interface of the HVAC controller.

Abstract: The invention pertains to penile implants that facilitate tissue expansion while not substantially inhibiting normal anatomical movement. The implants may be made of different materials or made in different configurations such that such that a measured property at a first location on said implant is different than said same measured property at a second location on said implant.

Abstract: Implementations are described of a computing device that migrates data and software applications from a first computing device to a second computing device, in order to preserve data and other application-related customizations.

Abstract: Orthopedic fixation devices and methods of installing the same. The orthopedic fixation device may include a coupling element and a bone fastener, whereby the bone fastener can be loaded into the coupling element through the bottom of a bore in the coupling element.

Abstract: Techniques are described for managing creation and/or execution of distributed programs, such as for a group of multiple interrelated programs that are part of a service-oriented architecture or that otherwise interact during execution to provide a desired type of functionality. In at least some situations, the described techniques include performing decentralized choreographed distributed execution of a group of related programs, by using executing supervisor components for some or all such programs to manage execution-related behavior of the programs. The execution-related behavior that is managed by supervisor components for a group of programs may include, for example, managing interactions between the programs, managing run-time dependencies and other relationships between at least some of the programs, managing update strategies for updating some or all of the programs of the group while the group continues to provide functionality (e.g.

Abstract: Generally, the instant disclosure relates to fertilizer compositions and methods of making and using the same. More specifically, the instant disclosure relates to blast suppressant and/or blast resistant ammonium nitrate fertilizer compositions, as well as methods of making and using the same.

Abstract: Users of client devices can take any number of actions using applications of an application system to achieve an outcome. A monitoring system aggregates the interactions into a user interaction path. Over time, the monitoring system generates a large number of user interaction paths. The monitoring system analyzes the user interaction paths for correlation between interactions and outcomes. The monitoring system can correlate user interaction paths to generated interactions of a system interaction path. The monitoring system determines a correlation between interactions and outcomes by calculating a success factor based on an efficiency score and a prevalence score. The success factor is a measure correlation between a particular interaction of the application system and an outcome, the prevalence score is a measure of how often a particular interaction occurs, and the efficiency score is a measure of the application system performance for a particular interaction.

Abstract: A system to enable a user to generate copies of files at a client device and to cause a file hosting platform to generate backups of these copies in a cloud database without transferring file content data for these files between the client device and the cloud database. When a user copies a file from a first folder on a client device to a second folder on the client device, the system may determine that the file content data for this file is already present in the cloud database. Then, rather than uploading the file content data to the cloud database from the client device, the system may cause a file hosting platform to access the file content data directly from the cloud database to perform a file copy operation.