Patents by Inventor David O. Barlow

David O. Barlow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amonafide salts
    Patent number: 6989390
    Abstract: Disclosed is a salt of amonafide or amonafide analogs represented Structural Formula (I): R1 is —(CH2)nN+HR3R4 X? or R1 is —(CH2)nN+HR3R4 X? or —(CH2)nNR3R4 when R2 is —N+HR6R7. R2 is —OR5, halogen, —NR6R7, —N+HR6R7 X?? sulphonic acid, nitro, —NR5COOR5, —NR5COR5 or —OCOR5; R3 and R4 are independently H, C1-C4 alkyl group or, taken together with the nitrogen atom to which they are bonded, a non-aromatic nitrogen-containing heterocyclic group; each R5 is independently —H or a C1-C4 alkyl group; R6 and R7 are independently H, C1-C4 alkyl group or, taken together with the nitrogen atom to which they are bonded, a non-aromatic nitrogen-containing heterocyclic group; n is an integer from 0-3; and X? is the carboxylate anion of an organic carboxylic acid compound. Also disclosed are methods of preparing certain compounds represented by Structural Formula (I).
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: January 24, 2006
    Assignee: Xanthus Life Sciences, Inc.
    Inventors: Alfred M. Ajami, David O. Barlow
  • Amonafide salts
    Publication number: 20040132763
    Abstract: Disclosed is a salt of amonafide or amonafide analogs represented Structural Formula (I): 1
    Type: Application
    Filed: October 20, 2003
    Publication date: July 8, 2004
    Applicant: Xanthus Life Sciences, Inc.
    Inventors: Alfred M. Ajami, David O. Barlow
  • Amonafide salts
    Patent number: 6693198
    Abstract: Disclosed is a salt of amonafide or amonafide analogs represented Structural Formula (I): R1 is —(CH2)nN+HR3R4 X− or R1 is —(CH2)nN+HR3R4 X− or —(CH2)nNR3R4 when R2 is —N+HR6R7. R2 is —OR5, halogen, —NR6R7, —N+HR6R7 X− sulphonic acid, nitro, —NR5COOR5, —NR5COR5 or —OCOR5; R3 and R4 are independently H, C1-C4 alkyl group or, taken together with the nitrogen atom to which they are bonded, a non-aromatic nitrogen-containing heterocyclic group; each R5 is independently —H or a C1-C4 alkyl group; R6 and R7 are independently H, C1-C4 alkyl group or, taken together with the nitrogen atom to which they are bonded, a non-aromatic nitrogen-containing heterocyclic group; n is an integer from 0-3; and X− is the carboxylate anion of an organic carboxylic acid compound. Also disclosed are methods of preparing certain compounds represented by Structural Formula (I).
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: February 17, 2004
    Assignee: Xanthus Life Sciences, Inc.
    Inventors: Alfred M. Ajami, David O. Barlow
  • Amonafide salts
    Publication number: 20030203932
    Abstract: Disclosed is a salt of amonafide or amonafide analogs represented Structural Formula (I): 1
    Type: Application
    Filed: April 22, 2002
    Publication date: October 30, 2003
    Applicant: Xanthus Life Sciences, Inc.
    Inventors: Alfred M. Ajami, David O. Barlow