Abstract: Pharmaceutical compositions including an active ingredient and a stabilizer, as well as methods of manufacture of the compositions, and methods of their use. The composition may include the active ingredient dispersed throughout a matrix of the stabilizer. In some embodiments, the active ingredient and the stabilizer are intimately mixed in a matrix formulation. In some embodiments, the active ingredient is selected from 4 amino-3-(4-chlorophenyl)butanoic acid) (“baclofen”) and its pharmaceutically acceptable salts.

Abstract: A pole piece for a transmission electron microscope, the pole piece comprising an upper pole piece, containing a first pathway for an electron beam, a lower pole piece which is coupled to the upper pole piece and which contains a second pathway operatively connected to the first pathway, the upper pole piece and lower pole piece being separated by a gap between the first pathway and the second pathway. The pole piece has a mechanism which can extend or reduce the distance between the upper pole piece and the lower pole piece by changing the distance between the first pathway and the second pathway.

Abstract: Described are articles of wear having a base layer, a plurality of cooling zones positioned on the base layer so that substantially all of the plurality of cooling zones are positioned adjacent regions of a wearer's body having highly efficient heat transfer properties of a wearer when worn, and cooling material contained within the plurality of cooling zones. The article of wear is configured to reduce a wearer's body heat content through heat transfer from each region having highly efficient heat transfer properties to each cooling zone when the cooling material is pre-cooled prior to wearing.

Abstract: Described are articles of wear having a base layer, a plurality of cooling zones positioned on the base layer so that substantially all of the plurality of cooling zones are positioned adjacent regions of a wearer's body having highly efficient heat transfer properties of a wearer when worn, and cooling material contained within the plurality of cooling zones. The article of wear is configured to reduce a wearer's body heat content through heat transfer from each region having highly efficient heat transfer properties to each cooling zone when the cooling material is pre-cooled prior to wearing.

Abstract: Described are multilayered breathable and waterproof materials having at least two nonwoven fiber layers, each fiber layer including a plurality of unidirectionally oriented fibers coated with a matrix material. The fibers in a first one of the at least two nonwoven fibers layers form an angle of approximately 90° with respect to the fibers in another one of the at least two nonwoven fiber layers. An outer layer is adhered to a side of one of the at least two nonwoven fiber layers. A polyurethane inner membrane is adhered to another side of the at least two nonwoven fiber layers, wherein at least the inner membrane is embossed.

Abstract: An item of clothing that includes a first textile area that is suitable to receive at least one sensor, a second textile area, and a third textile area, which is arranged at least partially between the first and second textile areas. The third textile area is provided such that when the item of clothing is worn it isolates at least one motion between the first textile area and the second textile area, so that a sensor or sensors remain substantially fixed in relation to an area of a subjacent organ of a wearer of the item of clothing.