Patents by Inventor David Oare
David Oare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9242983Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: GrantFiled: April 8, 2014Date of Patent: January 26, 2016Assignees: K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
-
Patent number: 9139604Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.Type: GrantFiled: June 19, 2014Date of Patent: September 22, 2015Assignee: Gilead Sciences, Inc.Inventors: Constantine G. Boojamra, Carina E. Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Haolun Jin, Ralph Hirschmann, Alan X. Huang, Choung U. Kim, Thorsten A. Kirschberg, Christopher P. Lee, William A. Lee, Richard L. Mackman, David Y. Markevitch, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie O'Shea, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang
-
Publication number: 20150025039Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.Type: ApplicationFiled: June 19, 2014Publication date: January 22, 2015Inventors: Constantine G. BOOJAMRA, Carina E. CANNIZZARO, James M. CHEN, Xiaowu CHEN, Aesop CHO, Lee S. CHONG, Maria FARDIS, Haolun JIN, Ralph HIRSCHMANN, Alan X. HUANG, Choung U. KIM, Thorsten A. KIRSCHBERG, Christopher P. LEE, William A. LEE, Richard L. MACKMAN, David Y. MARKEVITCH, David A. OARE, Vidya K. PRASAD, Hyung-Jung PYUN, Adrian S. RAY, Rosemarie O'SHEA, Sundaramoorthi SWAMINATHAN, William J. WATKINS, Jennifer R. ZHANG
-
Patent number: 8871785Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.Type: GrantFiled: March 21, 2013Date of Patent: October 28, 2014Assignee: Gilead Sciences, Inc.Inventors: Constantine G. Boojamra, Carina E. Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Haolun Jin, Ralph Hirschmann, Alan X. Huang, Choung U. Kim, Thorsten A. Kirschberg, Christopher P. Lee, William A. Lee, Richard L. Mackman, David Y. Markevitch, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie O'Shea, Sundaramoorthi Swaninathan, William J. Watkins, Jennifer R. Zhang
-
Publication number: 20140221382Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: ApplicationFiled: April 8, 2014Publication date: August 7, 2014Applicant: GILEAD SCIENCES, INC.Inventors: Steven S. BONDY, David A. OARE, Gerhard PUERSTINGER
-
Patent number: 8722677Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: GrantFiled: June 22, 2012Date of Patent: May 13, 2014Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
-
Patent number: 8569487Abstract: A compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections. Methods of making and formulating compound (1) are provided.Type: GrantFiled: July 6, 2007Date of Patent: October 29, 2013Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, Terrence C. Dahl, David A. Oare, Reza Oliyai, Winston C. Tse, Vahid Zia
-
Patent number: 8329727Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one imidazo[4,5-c]pyridine prodrug having the general Formula (A) wherein the substituents are described in the specification. The invention also relates to processes for the preparation and screening of compounds according to the invention having above mentioned general Formula and their use in the treatment or prophylaxis of viral infections.Type: GrantFiled: October 13, 2009Date of Patent: December 11, 2012Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, Eric Davis Dowdy, Choung U. Kim, David A. Oare, Johan Neyts, Vahid Zia, Gerhard Pürstinger
-
Publication number: 20120258969Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: ApplicationFiled: June 22, 2012Publication date: October 11, 2012Inventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
-
Patent number: 8263612Abstract: Pyrrolo[2,3-c]pyridine or pyrrolo[3,2-c]pyridine compounds having the general formula (A), wherein the dashed lines, X, Y and R1 through R5 are as defined in the specification. The compounds are useful in the prophylaxis or treatment of viral infections.Type: GrantFiled: December 14, 2007Date of Patent: September 11, 2012Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, David A. Oare, Gerhard Puerstinger
-
Patent number: 8080565Abstract: This invention provides 4-amino-1-benzylpiperidine and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; processes and intermediates useful for preparing such compounds; and methods for treating disease conditions mediated by muscarinic receptors, such as overactive bladder, irritable bowel syndrome, asthma and chronic obstructive pulmonary disease, using such compounds.Type: GrantFiled: March 6, 2008Date of Patent: December 20, 2011Assignee: Theravance, Inc.Inventors: Mathai Mammen, Richard Wilson, Sarah Dunham, Adam Hughes, Craig Husfeld, Yu-Hua Ji, Li Li, Trevor Mischki, Ioanna Stergiades, David Oare
-
Publication number: 20110288053Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.Type: ApplicationFiled: July 20, 2011Publication date: November 24, 2011Applicant: Gilead Sciences, Inc.Inventors: Constantine G. Boojamra, Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Heolun Jin, Ralph F. Hirschmann, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Christopher P. Lee, William A. Lee, Richard L. Mackman, David Y. Markevitch, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoothi Swaninathan, William J. Watkins, Jenneifer Zhang
-
Patent number: 8030502Abstract: This invention provides 4-amino-1-(pyridylmethyl)piperidine and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; processes and intermediates useful for preparing such compounds; and methods for treating disease conditions mediated by muscarinic receptors, such as overactive bladder, irritable bowel syndrome and chronic obstructive pulmonary disease, using such compounds.Type: GrantFiled: October 17, 2007Date of Patent: October 4, 2011Assignee: Theravance, Inc.Inventors: Mathai Mammen, David Oare, Junning Lee, Weijiang Zhang
-
Patent number: 8022083Abstract: The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.Type: GrantFiled: July 1, 2008Date of Patent: September 20, 2011Assignee: Gilead Sciences, Inc.Inventors: Constantine G. Boojamra, Carina Cannizzaro, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Haolun Jin, Ralph F. Hirschmann, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Christopher P. Lee, William A. Lee, Richard L. Mackman, David Y. Markevitch, David A. Oare, Vidya K. Prasad, Hyung-Jung Pyun, Adrian S. Ray, Rosemarie Sherlock, Sundaramoorthi Swaminathan, William J. Watkins, Jennifer R. Zhang
-
Patent number: 7956184Abstract: A compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating compound (1) are provided.Type: GrantFiled: February 18, 2010Date of Patent: June 7, 2011Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard PuerstingerInventors: Steven S. Bondy, David A. Oare, Winston C. Tse
-
Publication number: 20110071101Abstract: The invention is related to phosphorus substituted nucleoside compounds and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.Type: ApplicationFiled: April 9, 2008Publication date: March 24, 2011Inventors: Constantine G. Boojamra, James M. Chen, Xiaowu Chen, Aesop Cho, Lee S. Chong, Maria Fardis, Alan X. Huang, Choung U. Kim, Thorsten Kirschberg, Christopher P. Lee, David A. Oare, Vidya K. Prasad, Adrian S. Ray, Sundaramoorthi Swaminathan, William J. Watkins
-
Patent number: 7842672Abstract: A compound of Formula I, Formula II, Formula III, or Formula IV: or a pharmaceutically acceptable salt, solvate, and/or ester thereof, therapeutic compositions containing such compounds, and therapeutic methods that include the administration of such compounds.Type: GrantFiled: July 6, 2007Date of Patent: November 30, 2010Assignee: Gilead Sciences, Inc.Inventors: Constantine G. Boojamra, James M. Chen, Alan X. Huang, Choung U. Kim, Kuei-Ying Lin, Richard L. Mackman, David A. Oare, Jason K. Perry, Oliver L. Saunders, Sundaramoorthi Swaminathan, Lijun Zhang
-
Patent number: 7795276Abstract: The compound 5-((3-(2,4-trifluoromethyphenyl)isoxazol-5-yl)methyl)-2 -(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine, together with the salts and solvates thereof. Also provided are compositions comprising this compound and pharmaceutically acceptable carriers, as well as the use of such compositions in the treatment or prophylaxis of viral infections.Type: GrantFiled: January 30, 2008Date of Patent: September 14, 2010Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Steven S. Bondy, David A. Oare, Winston C. Tse
-
Patent number: 7790730Abstract: The present invention relates to pharmaceutical compositions for the treatment or prevention of viral infections comprising as an active principle at least one compound having the general formula (A): wherein U is N or C; X is selected from C1-C10 alkylene, C2-10 alkenylene or C2-10 alkynylene, where each may include one or more intrachain heteroatoms selected from O, S, or NR11, provided any such heteroatom is not adjacent to the N in the ring; R3 is selected from aryl, aryloxy, arylthio, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl-N(R10)—, or heterocycle, where each said substituent is optionally substituted with at least one R17, provided that for cycloalkenyl the double bond is not adjacent to a nitrogen; and the other substituents are described in the specification.Type: GrantFiled: July 26, 2005Date of Patent: September 7, 2010Assignees: Gilead Sciences, Inc., K.U. Leuven Research & DevelopmentInventors: Choung U. Kim, Johan Neyts, David A. Oare, Gerhard Puerstinger
-
Patent number: 7754720Abstract: A compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating compound (1) are provided.Type: GrantFiled: July 6, 2007Date of Patent: July 13, 2010Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard PuerstingerInventors: Steven S. Bondy, Terrence C. Dahl, David A. Oare, Reza Oliyai, Winston C. Tse, Vahid Zia