Abstract: Apparatus and methods for practicing telemedicine in the form of software systems acting over a network and kits containing laboratory supplies and equipment to organize the laboratory operations and interpret the results of molecular diagnostic testing are disclosed. At least two computers in communication over the Internet or other network are used, a remote computer located at a remote site and a central server located at a central site. The remote site may be geographically distant from the central site. A specimen is procured from a patient proximate to the remote site. Laboratory operations are conducted on the specimen at the remote site. The laboratory data resulting from the laboratory operations is interpreted by an expert reviewer who may be located at the central site, and a report is then transmitted back to the remote site.

Abstract: A digital signal line transmission system with reduced echo is provided. A communication line is between a carrier and a user terminal. A bridgetap line has a first end connected to the communication line. An adaptor having a capacitance is connected to the bridgetap line. The adaptor reduces the effect of echo from the bridgetap line on a rate of data transmission to the user terminal over the communication line.

Abstract: External energy source, external charger, system of transcutaneous energy transfer, system of transcutaneous charging and method thereof. An implantable medical device has a secondary coil operatively coupled to therapeutic componentry. An external power source has a housing, a primary coil carried in the housing with the primary coil being capable of inductively energizing the secondary coil when the housing is externally placed in proximity of the secondary coil with a first surface of the housing positioned closest to the secondary coil and a thermo-electric cooling device placed associated with the first surface of the housing.

Abstract: System for transcutaneous energy transfer. An implantable medical device, adapted to be implanted in a patient, has componentry for providing a therapeutic output. The implantable medical device has an internal power source and a secondary coil operatively coupled to the internal power source. An external power source, having a primary coil, provides energy to the implantable medical device when the primary coil of the external power source is placed in proximity of the secondary coil of the implantable medical device and thereby generates a current in the internal power source. An alignment indicator reports the alignment as a function of the current generated in the internal power source with a predetermined value associated with an expected alignment between the primary coil and secondary coil.

Abstract: Methods and compositions for preparation of biological samples are disclosed. The methods include a prelysis step and a lysis step to make the cellular DNA available for further processing, amplification or analysis. The prelysis step includes the addition of a prelysis reagent to the cells. The prelysis reagent may include an enzyme to facilitate the disruption of the cells. The lysis step includes the addition of a lysis reagent to at least a portion of the prelysis reagent and cells.

Abstract: A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.

Abstract: A fiber channel storage area network (SAN) provides virtualized storage space for a number of servers to a number of virtual disks implemented on various virtual redundant array of inexpensive disks (RAID) devices striped across a plurality of physical disk drives. The SAN includes plural controllers and communication paths to allow for fail-safe and fail-over operation. The plural controllers can be loosely-coupled to provide n-way redundancy and have more than one independent channel for communicating with one another. In the event of a failure involving a controller or controller interface, the virtual disks that are accessed via the affected interfaces are re-mapped to another interface in order to continue to provide high data availability. In particular, those targets, or virtual disks, which are owned by a failed device (e.g.

Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.

Abstract: Microstructured optical films, assemblies of films including at least one microstructured optical film, and (e.g. illuminated) display devices including a single microstructured optical film or assembly.

Abstract: Light management films and methods of making light management films are described. The light management films contain an optical layer that contains polymeric material and zirconia particles. The zirconia particles are colloidal, crystalline, substantially non-associated, and have a narrow size distribution.

Abstract: Presently described are microstructured articles such as a brightness enhancing film or optical turning film comprising a polymerized structure comprising the reaction product of a polymerizable composition comprising an (A) organic component comprising (i) at least one monofunctional acrylic monomer selected from t-alkyl (meth)acrylates, N-substituted or N,N-disubstituted (meth)acrylamides, and C1-8 primary or secondary alkyl (meth)acrylate; (ii) at least one multifunctional (meth)acrylate or (meth)acrylamide monomer; (iii) optionally, at least one oligomeric (meth)acrylate; and (iv) at least one photoinitiator; and (B) at least 10 wt-% inorganic nanoparticles.

Abstract: Polymerizable compositions comprising particularly useful for brightness enhancing films.

Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.

Abstract: The development of new compositions and new aromatic sulfur acrylate monomers results in improved hardcoat films, and improved optical films that contain the hard coat films. The films provide improved display systems when incorporated thereon. The combination of functionalized zirconia nanoparticles with multifunctional acrylate crosslinkers and high index of refraction aromatic sulfur acrylates, about 1.58 or greater, produces abrasion resistant hard coats that have relatively high refractive indices.

Abstract: A fiber channel storage area network (SAN) provides virtualized storage space for a number of servers to a number of virtual disks implemented on various virtual redundant array of inexpensive disks (RAID) devices striped across a plurality of physical disk drives. The SAN includes plural controllers and communication paths to allow for fail-safe and fail-over operation. The plural controllers can be loosely-coupled to provide n-way redundancy and more than one independent channel for communicating with one another. In the event of a failure involving a controller or controller interface, the virtual disks that are accessed via the affected interfaces are re-mapped to another interface in order to continue to provide high data availability. In particular a resource re-allocation routine operating on one of the controllers employs predetermined criteria against a family of potential back-up controllers in order to select appropriate back-up controllers for a particular device that fails.

Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.

Abstract: A fiber channel storage area network (SAN) provides virtualized storage space for a number of servers to a number of virtual disks implemented on various virtual redundant array of inexpensive disks (RAID) devices striped across a plurality of physical disk drives. The SAN includes plural controllers and communication paths to allow for fail-safe and fail-over operation. The plural controllers can be loosely-coupled to provide n-way redundancy and have more than one independent channel for communicating with one another. In the event of a failure involving a controller or controller interface, the virtual disks that are accessed via the affected interfaces are re-mapped to another interface in order to continue to provide high data availability.

Abstract: An online device and method for predicting at least one fluid flow parameter in a process (which comprises a bounded flow domain having disposed therein a pre-determined matrix) includes a computer and/or process steps whereby: (i) a memory receives a database, the database comprising location information for a plurality of nodes or particle pathways in the matrix; (ii) input data is received from the process, and (iii) the at least one fluid flow parameter is calculated from the database and the input data. Preferably, structure and/or process steps are provided to adjust the database in the event that the input data does not correspond with at least one pre-determined flow state.

Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.

Abstract: Nanofilms useful for filtration are prepared from amphiphilic species and one or more polymeric components. The amphiphilic species or components may be oriented on an interface or surface. A nanofilm may be prepared by coupling one or more of the components. The nanofilm may also be deposited or attached to a substrate.