Abstract: A tactical rail for a firearm can include a rail body having a receiver end and a muzzle end, a non-contact optical connection arranged at an end of the rail body and configured to interface with a corresponding non-contact optical interface, and a high speed data spoke connected to the non-contact optical connection for high speed data communication with a high speed data accessory through the non-contact optical connection and the corresponding non-contact optical interface.

Abstract: Methods and devices for providing noninvasive electrotherapy and electrical stimulation are described herein. In one aspect, a device for noninvasive electrotherapy includes wireless communication circuitry configured to receive pulse generation control signals wirelessly transmitted from a computing device. The device can include pulse generation circuitry configured to deliver electrical waveforms according to instructions encoded in the pulse generation control signals. The computing device can include a cellular telephone device, a portable media player, a personal digital assistant, a tablet computer, or an internet access device.

Abstract: The invention relates to saRNA targeting an HNF4a transcript and therapeutic compositions comprising said saRNA. Methods of using the therapeutic compositions are also provided.

Abstract: Reduced-bandwidth versions of display signals that are currently being provided as outputs by multiple computer systems are received and processed for output, at another computer system, of a representation of each of the display signals. The received reduced-bandwidth versions may include, for example, versions of display signals that are generated by applying any one or more of the following to each of the display signals: scaling, segmenting, and compression. At a transmit side, respective requests for different reduced-bandwidth versions of a display signal that is currently being provided as an output by a computer system are received from multiple other computer systems. The different reduced-bandwidth versions of the display signal are generated and transmitted to the requesting computer systems responsive to the requests.

Abstract: Compounds having activity as inhibitors of NEK7 are provided. The compounds have Structure (I): or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof, wherein, A, X, Y, R1, R2, R3, R4 and R5 are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods to modulate the activity of the NLRP3 inflammasome are also provided.

Abstract: Embodiments of putter-type golf club head comprising a striking surface capable of achieving consistent ball speeds across the striking surface to account for various ball impact locations are described herein. The striking surface has at least two materials that differs in concentration away from the geometric center of the striking surface to provide this consistency. Consistent (or uniform) ball speed is achieved throughout the striking surface as the portion of the golf ball that contacts the striking surface interacts with at least two materials having a differing material characteristic.

Abstract: A system and method are provided for managing digital marketing to a multiplicity of consumers by way of portable wireless digital devices. The system comprises a simplified human-device interface stored on the portable wireless digital devices. An instrumentation subsystem collects interaction and behavioral data from the simplified human-device interface. A campaign management subsystem permits digital marketing content to be made available and the display of content options to be defined to operate in a controlled way. An analytics subsystem processes the interaction and behavioral data in accordance with a knowledge the states of each of the consumers to permit controlling marketing content and promotions to the consumer. A display subsystem stored on the portable wireless digital device controls the display of marketing content and promotions at specific locations within the human-device interface.

Abstract: The present invention provides a supercapacitor assembly which is characterised by comprising: a supercapacitor comprised of carbon-containing anode(s) and cathode(s), intermediate porous membrane(s) and an ionic liquid electrolyte; an electrical heater for heating the supercapacitor; and a thermostat for controlling the heater and maintaining the temperature of the ionic liquid at a temperature such that its viscosity is in the range 1 to 50 centipoise. In particular, there are provided supercapacitors which can operate at voltages greater than 3.5v (for example, in the range 3.5 to 6v) without significant long term redox degradation.

Abstract: Techniques for forking and merging of electronically presented content items, such as MMO and other video games, are described herein. In particular, a first content item session may be forked to generate a second (forked) content item session. The first and forked content item sessions may then continue to execute and evolve in separate directions from one another. In some examples, a user of the forked content item session may serve as an administrator of the forked content item session and may receive compensation in exchange for serving as an administrator. Additionally, one or more forked or other separate content item sessions may be merged together to form a merged content item session. In some examples, conflicts between merged content item sessions may be identified and resolved based, at least in part, on input from administrators.

Abstract: An apparatus for power conversion comprises a voltage transformation element, a regulating element, and a controller; wherein, a period of the voltage transformation element is equal to a product of a coefficient and a period of the regulating circuit, and wherein the coefficient is selected from a group consisting of a positive integer and a reciprocal of said integer.

Abstract: A lower-dimensional representation (e.g., approximation) of a dataset is determined. The lower-dimensional representation can be used, for example, to perform semantic document analysis. Given a matrix of input data points, where each entry of the matrix indicates a number of times a particular term in a set of terms appears in a particular document in a set of documents, a lower-dimensional compressed matrix is obtained from the matrix by sampling rows of the matrix based on a target rank parameter, a desired accuracy tolerance, leverage scores calculated for the rows, and/or distances from rows of the matrix to a span of the initial set of sampled rows. The compressed matrix is used to determine a similarity metric indicative of a degree of similarity between documents. The documents can then be classified into a same document cluster or different clusters based on whether the similarity metric satisfied a threshold value.

Abstract: A vehicle frame assembly includes, among other things, a lower main rail of a vehicle, a deflector assembly that is disposed adjacent a forward end portion of the lower main rail, and a positioning bracket of the deflector assembly. The positioning bracket is secured directly to the lower main rail and configured to separate from the lower main rail if a load that exceeds a threshold load is applied to a front of the vehicle.

Abstract: Many environments or operational conditions create repetitive radio frequency (RF) interference conditions resulting from repetitive mechanical or electrical activity. This activity may create oscillations in the RF conditions between an MTC UE and a serving base station. Aspects of the present invention are directed to improving data efficiency and battery life by optimizing communication based on a detected periodicity of repetitive mechanical or electrical activity at the UE by monitoring the oscillations of at least one RF condition between the MTC UE and the base station, and scheduling communication between the UE and the network during periods associated with favorable radio conditions.

Abstract: Aspects of the subject disclosure may include, for example, obtaining a first group of video content streams of an event, determining a first point of view of a plurality of audience members of the event, and selecting a first portion of the first group of video content streams of the event according to the first point of view of the plurality of audience members. Further aspects can include aggregating the first portion of the first group of video content streams resulting in first aggregated video content, generating first augmented reality content from the first aggregated video content according to the first point of view, and providing the first augmented reality content to a communication device. The communication device can present the first augmented reality content. Other embodiments are disclosed.

Abstract: An implantable intracardiac device to prevent systolic anterior motion of the anterior mitral valve leaflet into the left ventricular outflow tract is described. The device comprises a blocking member configured for implantation within the left ventricle of the heart and in-situ blocking of systolic anterior motion of the mitral valve into the left ventricular outflow tract when anchored into the left ventricle of the heart. The device may be configured for radial expansion from a contracted orientation suitable for transluminal delivery to the left ventricle of the heart within a suitable delivery vehicle and an expanded orientation suitable for deployment within the left ventricle of the heart. The device comprises anchors configured for anchoring the device in-situ within the left ventricle to a wall of the left ventricle.

Abstract: A continuous flow granular/flocculent sludge wastewater process selects for granule biomass capable of nitrogen and phosphorus removal and controls granule size and concentration of granular and flocculent sludge for optimal nutrient, organic, and solids removal in a smaller footprint. A series of biological process zones lead to a secondary clarifier. Mixed liquor sludge, preferably from an aerobic zone, goes through a classifier or separator processing flow from the aerobic zone, to the secondary clarifier. In a sidestream process that can be included a portion of sludge preferably from an aerobic zone goes through a classifier or separator to selectively produce a granular-rich effluent, and the clarifier may also have a separator to further concentrate granular biomass, most of which is cycled back to an initial multi-stage anaerobic process zone. The anaerobic zone is structured and operated to encourage growth of granules in subsequent process zones.

Abstract: A method performed by a network device includes: receiving a first packet by the network device, wherein the first packet is tapped from a network; identifying a session to which the first packet belongs when the first packet has one or more values that at least partially match one or more terms, wherein the act of identifying the session is performed by the network device; receiving a second packet by the network device; determining whether the second packet belongs to the session; and performing a packet processing action by the network device based on the identified session; wherein the session is identified based on a first criterion, and the act of determining whether the second packet belongs to the session is performed based on a second criterion that is different from the first criterion.

Abstract: The present invention provides for novel metabolic pathways to convert biomass and other carbohydrate sources to malonyl-CoA derived products, such as hydrocarbons and other bioproducts, under anaerobic conditions and with the net production of ATP. More specifically, the invention provides for a recombinant microorganism comprising one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to achieve conversion of a carbohydrate source to, e.g., long-chain hydrocarbons and hydrocarbon derivatives, wherein the one or more native and/or heterologous enzymes is activated, upregulated, downregulated, or deleted. The invention also provides for processes to convert biomass to malonyl-CoA derived products which comprise contacting a carbohydrate source with a recombinant microorganism of the invention.

Abstract: A system for managing systems with interrelated microservices with self-assembling and self-configuring microservices includes a plurality of host resource services microservices, a plurality of directory services microservices and a plurality of tenant microservices. Each of the microservices is provided with an API with a standard way to identify the API and its components, which together identify the functionality of the API in a common way. The host resources service microservice are started up in a host. A determination is made whether there is a directory service microservice running in the host and, if there is none, then spinning up a directory service microservice. A plurality of tenant microservices are installed and a determination is made whether all tenant microservices are running, If not, then copies of the tenant microservices that are not running are spun up.