Patents by Inventor David Orain

David Orain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzamides Useful as S1P Receptor Modulators
    Publication number: 20100197753
    Abstract: The invention relates to novel aromatic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, b their use as medicaments and to medicaments comprising them.
    Type: Application
    Filed: May 20, 2008
    Publication date: August 5, 2010
    Inventors: Henri Mattes, Joachim Nozulak, David Orain, Kumlesh K. Dev
  • Bicyclic S1P Receptor Modulators
    Publication number: 20100179153
    Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, b their use as medicaments and to medicaments comprising them.
    Type: Application
    Filed: April 21, 2008
    Publication date: July 15, 2010
    Inventors: Henri Mattes, Joachim Nozulak, David Orain, Kumlesh K. Dev
  • 1H-QUINAZ0LINE-2,4-DIONES
    Publication number: 20100144747
    Abstract: The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) are and combinations comprising compounds of formula (I) are disclosed.
    Type: Application
    Filed: September 29, 2009
    Publication date: June 10, 2010
    Inventors: Hans ALLGEIER, Yves AUBERSON, David CARCACHE, Philipp FLOERSHEIM, Christel GUIBOURDENCHE, Wolfgang FROESTL, Jörg KALLEN, Manuel KOLLER, Henri MATTES, Joachim NOZULAK, David ORAIN, Johanne RENAUD
  • Substituted 1H-quinazoline-2,4-diones useful as AMPA receptor ligands
    Patent number: 7655666
    Abstract: The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) are and combinations comprising compounds of formula (I) are disclosed.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: February 2, 2010
    Assignee: Novartis AG
    Inventors: Hans Allgeier, Yves Auberson, David Carcache, Philipp Floersheim, Christel Guibourdenche, Wolfgang Froestl, Jörg Kallen, Manuel Koller, Henri Mattes, Joachim Nozulak, David Orain, Johanne Renaud
  • ORGANIC COMPOUNDS
    Publication number: 20090099199
    Abstract: The invention relates to compound of the formula I wherein the substituents are as defined in the specification; in free base form or in acid addition salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: October 15, 2008
    Publication date: April 16, 2009
    Inventors: Joachim Nozulak, David Orain, Simona Cotesta
  • ORGANIC COMPOUNDS
    Publication number: 20090099243
    Abstract: The invention relates to compound of the formula (I) in which the substituents are as defined in the specification; in free base form or in acid addition salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: October 15, 2008
    Publication date: April 16, 2009
    Inventors: Joachim Nozulak, David Orain
  • ORGANIC COMPOUNDS
    Publication number: 20090099244
    Abstract: The invention relates to compound of the formula I wherein the substituents are as defined in the specification; in free base form or in acid addition salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: October 15, 2008
    Publication date: April 16, 2009
    Inventors: Joachim Nozulak, David Orain
  • Organic Compounds
    Publication number: 20090005363
    Abstract: The present invention relates to novel nicotinic acid derivatives, of formula (I) wherein the substituents are defined in the specification, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: December 18, 2006
    Publication date: January 1, 2009
    Inventors: Ralf Glatthar, David Orain, Carsten Spanka
  • 1H-Quinazoline-2,4-Diones
    Publication number: 20080153836
    Abstract: The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) are and combinations comprising compounds of formula (I) are disclosed.
    Type: Application
    Filed: April 10, 2006
    Publication date: June 26, 2008
    Inventors: Hans Allgeier, Yves Auberson, David Carcache, Philipp Floersheim, Christel Guibourdenche, Wolfgang Froestl, Jorg Kallen, Manuel Koller, Henri Mattes, Joachim Nozulak, David Orain, Johanne Renaud
  • Quinazoline Derivatives
    Publication number: 20070208018
    Abstract: The present invention relates to 1H-Quinazoline-2,4-dione derivatives of formula(I) wherein the substituents are defined as in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them.
    Type: Application
    Filed: July 26, 2005
    Publication date: September 6, 2007
    Applicant: NOVARTIS AG
    Inventors: Hans Allgeier, Wolfgang Froestl, Manuel Koller, Henri Mattes, Joachim Nozulak, Silvio Ofner, David Orain, Vittorio Rasetti, Johanne Renaud, Nicolas Soldermann, Philipp Floersheim