Patents by Inventor David Orlando

David Orlando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240160284
    Abstract: Disclosed herein are an exemplary apparatus, system, and methods (e.g., Tactical Passive RFID transponder gloves with Morphological Actuation) comprising a glove made predominately of a resistive fabric that varies resistance per degree of deformation; comprising near field communication RFID tag readers, and a controller coupled to the glove to evaluate the varied resistance. A method of classifying RFID tags is also disclosed.
    Type: Application
    Filed: July 7, 2023
    Publication date: May 16, 2024
    Inventors: Erick Niels Maxwell, Eres David, Steven Paul Eicholtz, Samuel Finlayson, Dean Fullerton, John Kealy, Cameron Lewis, Michael Matthews, Dante Gabriel Orlando, Jacqueline Ramirez-Medina, Jonathan Ridley, Kelden Robinson, Rudra Pratap Singh, Daniel Andrew Terrell, Samrin Zaman
  • Publication number: 20230250145
    Abstract: The disclosure provides compositions and methods for the selective targeting of components of a first or a second DNA repair pathway in cancer cells having an impaired, defective or deregulated first DNA repair pathway. In some embodiments of the disclosure, the disclosure provides a composition comprising a DNA ligase 1 (LIG1) blocking agent, wherein in a target cell comprising an impaired, defective or deregulated homologous recombination (HR) repair pathway, the blocking agent reduces or inhibits a function of LIG1. In some embodiments of the disclosure, the disclosure provides composition comprising a Fanconi Anemia Group M protein (FANCM) blocking agent, wherein in a target cell comprising an impaired, defective or deregulated homologous recombination (HR) repair pathway, the blocking agent reduces or inhibits a function of FANCM. The disclosure further provides methods for using compositions of the disclosure for the treatment of cancer.
    Type: Application
    Filed: June 23, 2021
    Publication date: August 10, 2023
    Inventors: Andrew GARNER, Agustin CHICAS, David ORLANDO
  • Patent number: 11643920
    Abstract: A method includes deploying a logging tool in a borehole formed in a subsurface formation, the logging tool having a transmitter and a receiver, wherein a condition that is present during logging comprises at least one of a shape of the borehole is non-circular and the logging tool is off-center within the borehole. The method includes emitting, by the transmitter, a signal into subsurface formation and detecting, by the receiver, a response to the signal being propagated through the subsurface formation. The method includes creating, from the response, a borehole image that includes features in the subsurface formation and correcting the features, wherein correcting the features comprises mapping points of a non-circular shape in the borehole image into a plane substantially perpendicular to an axis of the borehole.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: May 9, 2023
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Nam Nguyen, David Orlando Torres, Gary Wayne Kainer
  • Publication number: 20230042181
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Application
    Filed: July 22, 2022
    Publication date: February 9, 2023
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael Robert McKeown, David A. Orlando
  • Publication number: 20220325904
    Abstract: Auxiliary system for a low-temperature remote thermal energy distribution network (anergy network) connected to user thermal installations, comprising one or more heat pumps thermally coupled to the anergy network via a heat exchanger, one or more air-liquid heat exchangers thermally coupled to the outside air, and a hydraulic network interconnecting the heat pumps to the heat exchanger of the anergy network, at least one of the heat pumps being a liquid-air heat pump fluidically connected by the hydraulic network to at least one of said air-liquid heat exchangers. The auxiliary system further comprises a measurement, control and regulation (MCR) system. The hydraulic network comprises valves controlled by the MCR system and a hydraulic circuit configured to allow direct connection of said air-liquid heat exchangers to the heat exchanger of the anergy network.
    Type: Application
    Filed: September 8, 2020
    Publication date: October 13, 2022
    Applicant: APTERIX SA
    Inventor: David Orlando
  • Patent number: 11447831
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: September 20, 2022
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael Robert McKeown, David A. Orlando
  • Patent number: 11442188
    Abstract: A method for imaging a downhole formation. The method includes combining the captured images to generate a partial image of the formation, wherein the partial image includes captured images separated by gaps representing portions of the formation not captured with sensors what were disposed downhole. The method includes locating dips in the formation within the partial image and interpolating the partial image using the located dips within the partial image.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: September 13, 2022
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Nam Nguyen, David Orlando Torres, Gary Wayne Kainer
  • Patent number: 11339646
    Abstract: A method for identifying a shape of a borehole may comprise disposing a downhole tool into the borehole, wherein the downhole tool comprises at least one transducer, transmitting a pressure pulse from the at least one transducer, wherein the pressure pulse is reflected as an echo, recording the echo with the at least one transducer, producing data points based at least in part on the echo, each data point including a radial distance value and an azimuthal value corresponding to the radial distance value, performing a pre-selection, fitting a geometric shape to a plurality of data points within the borehole, and sorting out at least one of the plurality of data points based at least in part on the shape. A system for identifying shape of a borehole may comprise at least one transducer and an information handling system.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: May 24, 2022
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Nam Nguyen, David Orlando Torres, Gary Wayne Kainer
  • Publication number: 20220154572
    Abstract: A method includes deploying a logging tool in a borehole formed in a subsurface formation, the logging tool having a transmitter and a receiver, wherein a condition that is present during logging comprises at least one of a shape of the borehole is non-circular and the logging tool is off-center within the borehole. The method includes emitting, by the transmitter, a signal into subsurface formation and detecting, by the receiver, a response to the signal being propagated through the subsurface formation. The method includes creating, from the response, a borehole image that includes features in the subsurface formation and correcting the features, wherein correcting the features comprises mapping points of a non-circular shape in the borehole image into a plane substantially perpendicular to an axis of the borehole.
    Type: Application
    Filed: January 28, 2022
    Publication date: May 19, 2022
    Inventors: Nam Nguyen, David Orlando Torres, Gary Wayne Kainer
  • Patent number: 11248457
    Abstract: A method includes deploying a logging tool in a borehole formed in a subsurface formation. The logging tool has a transmitter and a receiver. The method includes emitting, by the transmitter, a signal into subsurface formation. The method includes detecting, by the receiver, a response to the signal being propagated through the subsurface formation. The method includes creating, from the response, a borehole image that includes distorted features representing bedding dips in the subsurface formation. The method includes correcting the distorted features, wherein correcting the distorted features comprises mapping points of a non-circular shape in the borehole image to points on a circular shape.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: February 15, 2022
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Nam Nguyen, David Orlando Torres, Gary Wayne Kainer
  • Publication number: 20210356615
    Abstract: A method for imaging a downhole formation. The method includes combining the captured images to generate a partial image of the formation, wherein the partial image includes captured images separated by gaps representing portions of the formation not captured with sensors what were disposed downhole. The method includes locating dips in the formation within the partial image and interpolating the partial image using the located dips within the partial image.
    Type: Application
    Filed: March 28, 2019
    Publication date: November 18, 2021
    Inventors: Nam Nguyen, David Orlando Torres, Gary Wayne Kainer
  • Publication number: 20210332692
    Abstract: A method includes deploying a logging tool in a borehole formed in a subsurface formation. The logging tool has a transmitter and a receiver. The method includes emitting, by the transmitter, a signal into subsurface formation. The method includes detecting, by the receiver, a response to the signal being propagated through the subsurface formation. The method includes creating, from the response, a borehole image that includes distorted features representing bedding dips in the subsurface formation. The method includes correcting the distorted features, wherein correcting the distorted features comprises mapping points of a non-circular shape in the borehole image to points on a circular shape.
    Type: Application
    Filed: December 17, 2018
    Publication date: October 28, 2021
    Inventors: Nam Nguyen, David Orlando Torres, Gary Wayne Kainer
  • Publication number: 20210079786
    Abstract: A method for identifying a shape of a borehole may comprise disposing a downhole tool into the borehole, wherein the downhole tool comprises at least one transducer, transmitting a pressure pulse from the at least one transducer, wherein the pressure pulse is reflected as an echo, recording the echo with the at least one transducer, producing data points based at least in part on the echo, each data point including a radial distance value and an azimuthal value corresponding to the radial distance value, performing a pre-selection, fitting a geometric shape to a plurality of data points within the borehole, and sorting out at least one of the plurality of data points based at least in part on the shape. A system for identifying shape of a borehole may comprise at least one transducer and an information handling system.
    Type: Application
    Filed: November 2, 2018
    Publication date: March 18, 2021
    Applicant: Halliburton Energy Services, Inc.
    Inventors: Nam Nguyen, David Orlando Torres, Gary Wayne Kainer
  • Publication number: 20200392583
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Application
    Filed: May 8, 2020
    Publication date: December 17, 2020
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael Robert McKeown, David A. Orlando
  • Patent number: 10697025
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Grant
    Filed: February 20, 2018
    Date of Patent: June 30, 2020
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: Mei W. Chen, Cindy Collins, Matthew L. Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael R. McKeown, David A. Orlando
  • Patent number: 10167518
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: January 1, 2019
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael R. Mckeown, David A. Orlando
  • Publication number: 20180187271
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Application
    Filed: February 20, 2018
    Publication date: July 5, 2018
    Inventors: Mei W. Chen, Cindy Collins, Matthew L. Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael R. McKeown, David A. Orlando
  • Publication number: 20180087115
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Application
    Filed: October 31, 2017
    Publication date: March 29, 2018
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael R. McKeown, David A. Orlando
  • Patent number: 9845508
    Abstract: The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: December 19, 2017
    Assignee: Syros Pharmaceuticals, Inc.
    Inventors: Mei Wei Chen, Cindy Collins, Matthew Lucas Eaton, Matthew G. Guenther, Nan Ke, Jeremy Lopez, Michael R. McKeown, David A. Orlando
  • Patent number: 9715037
    Abstract: An integrated acoustic and induction logging tool enables efficient logging operations and reduces logging string length. In some of the disclosed embodiments, an integrated acoustic and induction logging tool includes a mandrel compatible with acoustic logging operations and induction logging operations. The integrated acoustic and induction logging tool also includes an acoustic logging transducer set and an induction logging coil set, where a plurality of transducers of the acoustic logging transducer set are interspersed among a plurality of coils of the induction logging coil set along the mandrel. A related assembly method includes obtaining a mandrel compatible with acoustic logging and induction logging. The method also includes assembling an acoustic logging transducer set and an induction logging coil set along the mandrel, where a plurality of transducers of the acoustic logging transducer set are interspersed among a plurality of coils of the induction logging coil set along the mandrel.
    Type: Grant
    Filed: March 28, 2013
    Date of Patent: July 25, 2017
    Inventors: Evan Lloyd Davies, Dustin Riley Stubbs, David Orlando Torres