Patents by Inventor David Osborn

David Osborn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240271114
    Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: March 15, 2024
    Publication date: August 15, 2024
    Applicant: Novozymes A/S
    Inventors: Mark David WOGULIS, Leslie DEMARS, David OSBORN
  • Patent number: 11965189
    Abstract: The present invention relates to cellobiohydrolase variants having increased thermal activity or thermostability, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: March 24, 2017
    Date of Patent: April 23, 2024
    Assignee: Novozymes A/S
    Inventors: Mark Wogulis, Leslie DeMars, David Osborn
  • Publication number: 20220025348
    Abstract: The present invention relates to isolated polypeptides having xylanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.
    Type: Application
    Filed: December 10, 2019
    Publication date: January 27, 2022
    Applicant: NOVOZYMES A/S
    Inventors: Nikolaj Spodsberg, David Osborn
  • Patent number: 11053489
    Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: July 6, 2021
    Assignee: NOVOZYMES A/S
    Inventors: Mark Wogulis, Leslie Demars, Aubrey Jones, Hanshu Ding, David Osborn
  • Publication number: 20200325463
    Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 15, 2020
    Applicant: Novozymes A/S
    Inventors: Mark Wogulis, Leslie Demars, Aubrey Jones, Hanshu Ding, David Osborn
  • Publication number: 20200299664
    Abstract: The present invention relates to cellobiohydrolase variants having increased thermal activity or thermostability, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: March 24, 2017
    Publication date: September 24, 2020
    Applicant: Novozymes A/S
    Inventors: Mark Wogulis, Leslie DeMars, David Osborn
  • Patent number: 10738293
    Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: August 11, 2020
    Assignee: Novozymes A/S
    Inventors: Mark Wogulis, Leslie Demars, Aubrey Jones, Hanshu Ding, David Osborn
  • Patent number: 10260058
    Abstract: The present invention relates to beta-glucosidase variants, e.g., beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus. The present invention also relates to polynucleotides encoding the beta-glucosidase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the beta-glucosidase variants.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: April 16, 2019
    Assignee: Novozymes, Inc.
    Inventors: Mark Wogulis, Paul Harris, David Osborn
  • Publication number: 20190085309
    Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.
    Type: Application
    Filed: March 2, 2017
    Publication date: March 21, 2019
    Applicant: Novozymes A/S
    Inventors: Mark Wogulis, Leslie Demars, Aubrey Jones, Hanshu Ding, David Osborn
  • Publication number: 20180051306
    Abstract: The invention relates to processes of closing an observed gap in sugar yield between pure batch hydrolysis and a multi-stage hydrolysis containing a continuous reactor. Enzyme compositions containing varied ratios of cellulolytic composition and a hemicellulolytic composition preconditioning are used in multi-stage hydrolysis processes containing a continuous reactor in order to close the gap. Such enzyme compositions are useful in multi-stage saccharification of a lignocellulosic material, fermentation processes following multi-stage saccharification of a lignocellulosic material and in improving a glucose or xylose yield in multi-stage saccharification of a lignocellulosic material.
    Type: Application
    Filed: March 11, 2016
    Publication date: February 22, 2018
    Applicants: Novozymes A/S, Beta Renewables Spa
    Inventors: Jesper Frickmann, Johan Belfrage, Eric Abbate, David Osborn, Geoffrey Moxley, Daniele Riva, Piero Otonello, Simone Ferrero, Micol Purrotti, Stefano Paravisi, Chiara Prefumo
  • Publication number: 20180044707
    Abstract: The invention relates to processes of multi-stage hydrolysis where different enzyme compositions are added in at least two stages of hydrolysis. In a first stage, a first enzyme composition of xylanase, a beta-xylosidase and an endoglucanase is added, followed by a latter stage in which a second enzyme composition, a cellulolytic enzyme composition, is added. Also provided are processes for obtaining hydrolysis products and fermentation products using processes of the invention.
    Type: Application
    Filed: March 11, 2016
    Publication date: February 15, 2018
    Applicants: Novozymes A/S, Beta Renewables Spa
    Inventors: Jesper Frickmann, Johan Belfrage, Eric Abbate, David Osborn, Geoffrey Moxley, Daniele Riva, Piero Otonello, Simone Ferrero, Micol Purrotti, Stefano Paravisi, Chiara Prefumo
  • Publication number: 20170369860
    Abstract: The present invention relates to endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, expression vectors, and recombinant host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: January 6, 2016
    Publication date: December 28, 2017
    Applicant: Novozymes A/S
    Inventors: Robert Blazej, Charles Emrich, Nicholas Toriello, Hanshu Ding, David Osborn, Aubrey Jones
  • Publication number: 20170306312
    Abstract: The present invention relates to beta-glucosidase variants, e.g., beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus. The present invention also relates to polynucleotides encoding the beta-glucosidase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the beta-glucosidase variants.
    Type: Application
    Filed: June 8, 2017
    Publication date: October 26, 2017
    Inventors: Mark Wogulis, Paul Harris, David Osborn
  • Patent number: 9688975
    Abstract: The present invention relates to beta-glucosidase variants, e.g. beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus. The present invention also relates to polynucleotides encoding the beta-glucosidase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the beta-glucosidase variants.
    Type: Grant
    Filed: September 30, 2011
    Date of Patent: June 27, 2017
    Assignee: Novozymes, Inc.
    Inventors: Mark Wogulis, Paul Harris, David Osborn
  • Publication number: 20150379022
    Abstract: Embodiments of the disclosure can include MapReduce systems and methods with integral mapper and reducer compute runtime environments. An example system with an integral reducer compute runtime environment can include mappers and reducers executable on a computer cluster. The mappers can be operable to receive raw input data and generate first input data based on the raw input data. The mappers can be operable to generate first result data based on the first input data. Based on the first result data, the mappers can be operable to generate (K, V) pairs. The reducers can be operable to receive the (K, V) pairs and generate second input data based on the (K, V) pairs. The reducers can be operable to transmit the second input data to integral compute runtime environment being run within the reducers and operable to generate second result data based on the second input data. Based on the second result data, the reducers can be operable to generate output data.
    Type: Application
    Filed: June 27, 2014
    Publication date: December 31, 2015
    Inventors: Ernest Charles Puig, John A. Interrante, Mark David Osborn, Eric Pool
  • Publication number: 20150017670
    Abstract: The present invention relates to methods for analyzing degradation of a biomass material at a high dry weight percentage.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 15, 2015
    Inventors: Jason Quinlan, Brett McBrayer, Elena Vlasenko, David Osborn
  • Publication number: 20140329284
    Abstract: The present invention relates to chimeric polypeptides having beta-glucosidase activity.
    Type: Application
    Filed: September 28, 2012
    Publication date: November 6, 2014
    Inventors: Mark Wogulis, David Osborn, Tia Heu
  • Publication number: 20130217079
    Abstract: The present invention relates to variants of a parent beta-glucosidase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: September 30, 2011
    Publication date: August 22, 2013
    Applicant: Novozymes, Inc.
    Inventors: Mark Wogulis, Paul Harris, David Osborn
  • Patent number: 7455099
    Abstract: A technique is disclosed for evaluating and monitoring performance of a heat exchanger system. Operating parameters of the system are monitored and fouling factors for heat transfer surfaces of the exchanger are determined. Trending of fouling may be performed over time based upon the fouling factors, and a model of fouling may be selected from known sets of models, or a model may be developed or refined. Fluid treatment, such as water treatment regimes may be taken into account in evaluation of fouling. An automated knowledge based analysis algorithm may diagnose possible caused of fouling based upon sensed and observed parameters and conditions. Corrective actions may be suggested and the system controlled to reduce, avoid or correct for detected fouling.
    Type: Grant
    Filed: June 29, 2004
    Date of Patent: November 25, 2008
    Assignee: General Electric Company
    Inventors: Mark David Osborn, Vijaysai Prasad, Lijie Yu, Venkatarao Ryali, Sunil Shirish Shah, Ivy Wai Man Chong, Shirley Suet-Yee Au, Nishith Pramod Vora
  • Publication number: 20080243328
    Abstract: A method for diagnosing faults in a particular device within a fleet of devices is provided. The method comprises receiving performance data related to one or more parameters associated with a fleet of devices and processing the performance data to detect one or more trend shifts in the one or more parameters. The method then comprises detrending the one or more parameters to derive noise-adjusted performance data related to a particular parameter associated with a particular device. The method further comprises generating a fleet-based diagnostic model based on trend patterns and data characteristics associated with the fleet of devices. The fleet-based diagnostic model comprises one or more fuzzy rules defining one or more expected trend shift data ranges for the one or more parameters associated with the fleet of devices.
    Type: Application
    Filed: April 2, 2007
    Publication date: October 2, 2008
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Lijie Yu, Daniel Joseph Cleary, Mark David Osborn