Patents by Inventor David Osborn
David Osborn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260258386Abstract: The present invention relates to isolated polypeptides having xylanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.Type: ApplicationFiled: July 14, 2025Publication date: September 3, 2026Applicant: NOVOZYMES A/SInventors: Nikolaj Spodsberg, David Osborn
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Patent number: 12385027Abstract: The present invention relates to isolated polypeptides having xylanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.Type: GrantFiled: December 10, 2019Date of Patent: August 12, 2025Assignee: NOVOZYMES A/SInventors: Nikolaj Spodsberg, David Osborn
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Publication number: 20240271114Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: ApplicationFiled: March 15, 2024Publication date: August 15, 2024Applicant: Novozymes A/SInventors: Mark David WOGULIS, Leslie DEMARS, David OSBORN
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Patent number: 11965189Abstract: The present invention relates to cellobiohydrolase variants having increased thermal activity or thermostability, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: GrantFiled: March 24, 2017Date of Patent: April 23, 2024Assignee: Novozymes A/SInventors: Mark Wogulis, Leslie DeMars, David Osborn
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Publication number: 20220025348Abstract: The present invention relates to isolated polypeptides having xylanase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding modules. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding modules.Type: ApplicationFiled: December 10, 2019Publication date: January 27, 2022Applicant: NOVOZYMES A/SInventors: Nikolaj Spodsberg, David Osborn
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Patent number: 11053489Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.Type: GrantFiled: June 30, 2020Date of Patent: July 6, 2021Assignee: NOVOZYMES A/SInventors: Mark Wogulis, Leslie Demars, Aubrey Jones, Hanshu Ding, David Osborn
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Publication number: 20200325463Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.Type: ApplicationFiled: June 30, 2020Publication date: October 15, 2020Applicant: Novozymes A/SInventors: Mark Wogulis, Leslie Demars, Aubrey Jones, Hanshu Ding, David Osborn
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Publication number: 20200299664Abstract: The present invention relates to cellobiohydrolase variants having increased thermal activity or thermostability, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: ApplicationFiled: March 24, 2017Publication date: September 24, 2020Applicant: Novozymes A/SInventors: Mark Wogulis, Leslie DeMars, David Osborn
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Patent number: 10738293Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.Type: GrantFiled: March 2, 2017Date of Patent: August 11, 2020Assignee: Novozymes A/SInventors: Mark Wogulis, Leslie Demars, Aubrey Jones, Hanshu Ding, David Osborn
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Patent number: 10260058Abstract: The present invention relates to beta-glucosidase variants, e.g., beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus. The present invention also relates to polynucleotides encoding the beta-glucosidase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the beta-glucosidase variants.Type: GrantFiled: June 8, 2017Date of Patent: April 16, 2019Assignee: Novozymes, Inc.Inventors: Mark Wogulis, Paul Harris, David Osborn
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Publication number: 20190085309Abstract: The present invention relates to cellobiohydrolase variants, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.Type: ApplicationFiled: March 2, 2017Publication date: March 21, 2019Applicant: Novozymes A/SInventors: Mark Wogulis, Leslie Demars, Aubrey Jones, Hanshu Ding, David Osborn
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Publication number: 20180051306Abstract: The invention relates to processes of closing an observed gap in sugar yield between pure batch hydrolysis and a multi-stage hydrolysis containing a continuous reactor. Enzyme compositions containing varied ratios of cellulolytic composition and a hemicellulolytic composition preconditioning are used in multi-stage hydrolysis processes containing a continuous reactor in order to close the gap. Such enzyme compositions are useful in multi-stage saccharification of a lignocellulosic material, fermentation processes following multi-stage saccharification of a lignocellulosic material and in improving a glucose or xylose yield in multi-stage saccharification of a lignocellulosic material.Type: ApplicationFiled: March 11, 2016Publication date: February 22, 2018Applicants: Novozymes A/S, Beta Renewables SpaInventors: Jesper Frickmann, Johan Belfrage, Eric Abbate, David Osborn, Geoffrey Moxley, Daniele Riva, Piero Otonello, Simone Ferrero, Micol Purrotti, Stefano Paravisi, Chiara Prefumo
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Publication number: 20180044707Abstract: The invention relates to processes of multi-stage hydrolysis where different enzyme compositions are added in at least two stages of hydrolysis. In a first stage, a first enzyme composition of xylanase, a beta-xylosidase and an endoglucanase is added, followed by a latter stage in which a second enzyme composition, a cellulolytic enzyme composition, is added. Also provided are processes for obtaining hydrolysis products and fermentation products using processes of the invention.Type: ApplicationFiled: March 11, 2016Publication date: February 15, 2018Applicants: Novozymes A/S, Beta Renewables SpaInventors: Jesper Frickmann, Johan Belfrage, Eric Abbate, David Osborn, Geoffrey Moxley, Daniele Riva, Piero Otonello, Simone Ferrero, Micol Purrotti, Stefano Paravisi, Chiara Prefumo
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Publication number: 20170369860Abstract: The present invention relates to endoglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, expression vectors, and recombinant host cells comprising the polynucleotides; and methods of using the variants.Type: ApplicationFiled: January 6, 2016Publication date: December 28, 2017Applicant: Novozymes A/SInventors: Robert Blazej, Charles Emrich, Nicholas Toriello, Hanshu Ding, David Osborn, Aubrey Jones
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Publication number: 20170306312Abstract: The present invention relates to beta-glucosidase variants, e.g., beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus. The present invention also relates to polynucleotides encoding the beta-glucosidase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the beta-glucosidase variants.Type: ApplicationFiled: June 8, 2017Publication date: October 26, 2017Inventors: Mark Wogulis, Paul Harris, David Osborn
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Patent number: 9688975Abstract: The present invention relates to beta-glucosidase variants, e.g. beta-glucosidase variants of a parent Family GH3A beta-glucosidase from Aspergillus fumigatus. The present invention also relates to polynucleotides encoding the beta-glucosidase variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the beta-glucosidase variants.Type: GrantFiled: September 30, 2011Date of Patent: June 27, 2017Assignee: Novozymes, Inc.Inventors: Mark Wogulis, Paul Harris, David Osborn
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Publication number: 20150017670Abstract: The present invention relates to methods for analyzing degradation of a biomass material at a high dry weight percentage.Type: ApplicationFiled: December 20, 2012Publication date: January 15, 2015Inventors: Jason Quinlan, Brett McBrayer, Elena Vlasenko, David Osborn
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Publication number: 20140329284Abstract: The present invention relates to chimeric polypeptides having beta-glucosidase activity.Type: ApplicationFiled: September 28, 2012Publication date: November 6, 2014Inventors: Mark Wogulis, David Osborn, Tia Heu
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Publication number: 20130217079Abstract: The present invention relates to variants of a parent beta-glucosidase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.Type: ApplicationFiled: September 30, 2011Publication date: August 22, 2013Applicant: Novozymes, Inc.Inventors: Mark Wogulis, Paul Harris, David Osborn
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Patent number: 4806382Abstract: A method for modifying a PMMA surface by the gamma-irradiation induced polymerization thereon of N-vinylpyrrolidone, 2-hydroxyethylmethacrylate or a mixture thereof while maintaining the following conditions:(a) monomer concentration in the range of from about 0.5% to about 50%, by weight;(b) total gamma dose in the range of from about 0.01 to less than about 0.50 Mrad;(c) gamma dose rate in the range of from about 10 to about 2500 rads/minute; and(d) maintaining the molecular weight of the polymer in solution in the range of from about 250,000 to about 5,000,000.The invention also relates to modifying polypropylene, polyvinylidene fluoride, polycarbonate and silicon surfaces according to a similar method as well as materials produced by the above methods which are useful as ocular implants.Type: GrantFiled: April 10, 1987Date of Patent: February 21, 1989Assignee: University of FloridaInventors: Eugene P. Goldberg, Jim Burns, John W. Sheets, Jeffrey A. Larson, Sudesh Kumar, David Osborn