Patents by Inventor David Osterman

David Osterman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED mRNA ENCODING A URIDINE DIPHOPSPHATE GLUCURONOSYL TRANSFERASE AND USES THEREOF
    Publication number: 20190307857
    Abstract: The invention relates to methods and compositions for treating a UDP glucuronosyltransferase family 1 deficiency based on mRNA therapy.
    Type: Application
    Filed: December 9, 2016
    Publication date: October 10, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Melissa Lasaro, David Osterman, Haren Vasavada, Christian Cobaugh
  • FLAVIN DERIVATIVES
    Publication number: 20130029980
    Abstract: The present invention relates novel flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives.
    Type: Application
    Filed: April 6, 2011
    Publication date: January 31, 2013
    Inventors: Philip D. G. Coish, Brian R. Dixon, David Osterman, Paul Adrian Aristoff, Manuel Navia, Frank Sciavolino, Stephanie Avola, Nick Baboulas, Thomas R. Belliotti, Angelica Bello, Judd Berman, Robert A. Chrusciel, Bruce R. Evans, Harpreet Kaur, David Moon, Vinh Pham, Andrew Roughton, Phil Wickens, Jeffrey Wilson, Heinrich J. Schostarez
  • FLAVIN DERIVATIVES
    Publication number: 20120295903
    Abstract: The present invention relates novel flavin derivatives and other flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives. The invention also provides method of making novel flavin derivatives.
    Type: Application
    Filed: June 30, 2010
    Publication date: November 22, 2012
    Inventors: Kenneth F. Blount, Philip D.G. Coish, Brian R. Dixon, Jayhyuk Myung, David Osterman, Phil Wickens, Stephanie Avola, Nick Baboulas, Angelica Bello, Judd Berman, Harpreet Kaur, David Moon, Vinh Pham, Andrew Roughton, Jeffrey Wilson, Jeffrey A. Leiby, Dennis Underwood, Paul Adrian Aristoff, Heinrich J. Schostarez, Robert A. Chrusciel, Thomas R. Belliotti, Bruce R. Evans, Frank C. Sciavolino, Manuel A. Navia
  • DIAMINOPTERIDINE DERIVATIVES
    Publication number: 20120283219
    Abstract: The present invention relates novel diaminopteridine derivatives, their compositions and method of treatment comprising the same for use as anti-infectives.
    Type: Application
    Filed: March 25, 2010
    Publication date: November 8, 2012
    Inventors: Philip D.G. Coish, Phil Wickens, Brian R. Dixon, David Osterman, Uday R. Khire, Manuel Navia, Judd Berman, Harpreet Kaur, Jeffrey Wilson, Dennis Underwood
  • METHODS FOR SCREENING AND IDENTIFYING COMPOUNDS
    Publication number: 20120135417
    Abstract: Methods, compositions and assays that measure the effect of a test compound on induction of ligand-induced ribowitch-mediated transcription termination are disclosed. The methods and the assays are useful in identifying drug candidates that modulate transcription by binding to a riboswitch, for example.
    Type: Application
    Filed: June 2, 2010
    Publication date: May 31, 2012
    Inventors: Jayhyuk Myung, Kenneth F. Blount, Christen Douglas Forbes, David Osterman
  • FLAVIN DERIVATIVES
    Publication number: 20120077781
    Abstract: The present invention relates novel flavin derivatives and other flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives. The invention also provides method of making novel flavin derivatives.
    Type: Application
    Filed: August 11, 2009
    Publication date: March 29, 2012
    Inventors: Robert Gadwood, Harpreet Kaur, Kevin Kells, Jeffrey A. Leiby, David Moon, Vinh Pham, Philip D.G. Coish, Kenneth F. Blount, Brian R. Dixon, Jayhyuk Myung, David Osterman, Stephanie Avola, Nick Baboulas, Angelica Bello, Judd Berman, Bruce R. Evans, Tan Quach, Heinrich J. Schostarez, Frank C. Sciavolino, Dennis Underwood, Phil Wickens, Jeffrey Wilson, Justin Wu
  • Methods for screening and identifying compounds
    Publication number: 20060068456
    Abstract: The present invention relates to methods for assessing enzyme activity utilizing a phase partition system. In addition, the present invention also relates to methods for screening and identifying compounds that may be used, for example, for the treatment of diabetes, diabetes-related disorders, obesity, cardiovascular disease, cancer, and other diseases or disorders, using this phase partition system.
    Type: Application
    Filed: November 2, 2005
    Publication date: March 30, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: James Landro, David Osterman, Walter Pickett
  • Device and methods for measuring the response of a least one cell to a medium
    Publication number: 20050158845
    Abstract: An apparatus and methods for measuring response of at least one cell to a medium, the response of at least one cell to a medium being characterized by a reaction time. In one embodiment of the present invention, the device includes a membrane and a side substrate defining a sample well in communication with the ambient air and for receiving the at least one cell such that the membrane is underneath the at least one cell. A sensor is positioned underneath the second surface of the membrane, and an inlet is in fluid communication with the sample well. A medium is introduced into the chamber through the inlet to form a droplet that surrounds the cell, and the sensor measures the response of the cell to the medium at a time period shorter than the reaction time.
    Type: Application
    Filed: August 6, 2002
    Publication date: July 21, 2005
    Inventors: John Wikswo, David Osterman, Franz Baudenbacher, Owen McGuinness, Ales Prokop
  • Methods for screening and identifying compounds
    Publication number: 20050064531
    Abstract: The present invention relates to methods for assessing enzyme activity utilizing a phase partition system. In addition, the present invention also relates to methods for screening and identifying compounds that may be used, for example, for the treatment of diabetes, diabetes-related disorders, obesity, cardiovascular disease, cancer, and other diseases or disorders, using this phase partition system.
    Type: Application
    Filed: August 4, 2004
    Publication date: March 24, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: James Landro, David Osterman, Walter Pickett