Patents by Inventor David Owen Bates

David Owen Bates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10301264
    Abstract: Anti-angiogenic treatments, treatments of hyperpermeability disorders, treatments of neuropathic and neurodegenerative disorders, pain treatments, methods of reducing the risk of pre-eclampsia and compounds for use in such methods are described.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: May 28, 2019
    Assignee: The University of Nottingham
    Inventors: Steven James Harper, David Owen Bates, Melissa Gammons, Jonathan Morris
  • Publication number: 20150274668
    Abstract: Anti-angiogenic treatments, treatments of hyperpermeability disorders, treatments of neuropathic and neurodegenerative disorders, pain treatments, methods of reducing the risk of pre-eclampsia and compounds for use in such methods are described.
    Type: Application
    Filed: October 17, 2013
    Publication date: October 1, 2015
    Applicant: The University of Bristol
    Inventors: Steven James Harper, David Owen Bates, Melissa Gammons, Jonathan Morris
  • Patent number: 8530150
    Abstract: A method of detecting a risk of a pregnant female mammal developing pre-eclampsia or a complication linked thereto, or of a fetus of the pregnant female mammal developing a fetal or neonatal deficiency linked to maternal pre-eclampsia, comprises detecting the level of a VEGFxxxb in a sample from the pregnant female mammal at less than about 24 weeks of gestation and comparing the detected level with a reference level. A reduced level in the sample from the pregnant female mammal is indicative of a risk of the pregnant female mammal developing pre-eclampsia or a complication linked thereto or of the fetus developing the fetal or neonatal deficiency linked to maternal pre-eclampsia.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: September 10, 2013
    Assignee: The University of Bristol
    Inventors: David Owen Bates, Victoria Louise Bills, Steven James Harper, Yan Qiu
  • Publication number: 20120010138
    Abstract: The invention provides VEGFxxxb, or an agent which selectively promotes the expression of VEGFxxxb in preference to VEGFxxx in cells of a subject or in vitro, or an expression vector system which causes the expression of the VEGFxxxb in a host organism, for use in treating or preventing microvascular hyperpermeability disorders, or in regulating the pro-angiogenic pro-permeability properties of VEGFxxx isoforms, or in supporting epithelial cell survival without increased permeability, or in reducing the nature (for example the number density and/or size) of fenestrations of epithelial filtration membranes in vivo or in vitro.
    Type: Application
    Filed: May 23, 2011
    Publication date: January 12, 2012
    Inventors: David Owen Bates, Steven James Harper, Andrew Salmon
  • Publication number: 20110076259
    Abstract: A method of detecting a risk of a pregnant female mammal developing pre-eclampsia or a complication linked thereto, or of a fetus of the pregnant female mammal developing a fetal or neonatal deficiency linked to maternal pre-eclampsia, comprises detecting the level of a VEGFxxxb in a sample from the pregnant female mammal at less than about 24 weeks of gestation and comparing the detected level with a reference level. A reduced level in the sample from the pregnant female mammal is indicative of a risk of the pregnant female mammal developing pre-eclampsia or a complication linked thereto or of the fetus developing the fetal or neonatal deficiency linked to maternal pre-eclampsia.
    Type: Application
    Filed: September 24, 2010
    Publication date: March 31, 2011
    Inventors: David Owen Bates, Victoria Louise Bills, Steven James Harper, Yan Qiu