Patents by Inventor David P. Basile

David P. Basile has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO TREAT RENAL DISORDERS USING CALCIUM CHANNEL INHIBITORS
    Publication number: 20250073202
    Abstract: Disclosed are methods to treat a renal disorder in a mammal in need thereof by administering to the mammal in need of treatment an effective amount of a store operated calcium entry (SOCE) inhibitor or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 5, 2024
    Publication date: March 6, 2025
    Applicant: The Trustees of Indiana University
    Inventors: David P. Basile, Purvi Mehrotra, Michael S. Sturek
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PROPHYLAXIS OF A PERFUSION DISORDER
    Publication number: 20230181648
    Abstract: The present disclosure provides compositions and methods for the treatment or prophylaxis of a perfusion disorder, such as ischemia and/or reperfusion injury, in a subject's organ, tissue or extremity by preserving or improving endothelial function, reducing vascular injury, and/or promoting vascular repair. The disclosed compositions comprise endothelial colony-forming cells or a serum-free composition comprising chemically defined media conditioned by endothelial colony-forming cells.
    Type: Application
    Filed: September 2, 2022
    Publication date: June 15, 2023
    Inventors: Mervin C. Yoder, David P. Basile
  • METHODS TO TREAT RENAL DISORDERS USING CALCIUM CHANNEL INHIBITORS
    Publication number: 20210338630
    Abstract: Disclosed are methods to treat a renal disorder in a mammal in need thereof by administering to the mammal in need of treatment an effective amount of a store operated calcium entry (SOCE) inhibitor or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 4, 2019
    Publication date: November 4, 2021
    Applicant: The Trustees of Indiana University
    Inventors: David P. Basile, Purvi Mehrotra, Michael S. Sturek
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PROPHYLAXIS OF A PERFUSION DISORDER
    Publication number: 20190388477
    Abstract: The present disclosure provides compositions and methods for the treatment or prophylaxis of a perfusion disorder, such as ischemia and/or reperfusion injury, in a subject's organ, tissue or extremity by preserving or improving endothelial function, reducing vascular injury, and/or promoting vascular repair. The disclosed compositions comprise endothelial colony-forming cells or a serum-free composition comprising chemically defined media conditioned by endothelial colony-forming cells.
    Type: Application
    Filed: February 21, 2018
    Publication date: December 26, 2019
    Applicant: Indiana University Research and Technology Corporation
    Inventors: Mervin C. Yoder, David P. Basile