Abstract: Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

Abstract: An aircraft fixed receptacle connector and a ground supply free plug connector used in commercial and military aircraft. This high performance external power connector is capable of operating in the 120 KVA rating to meet the electrical load requirement on today's newer, larger, and higher capacity aircraft. An array of high amperage power contacts and conventional pin and socket relay contacts are used.

Abstract: An aircraft fixed receptacle connector and a ground supply free plug connector used in commercial and military aircraft. This high performance external power connector is capable of operating in the 120 KVA rating to meet the electrical load requirement on today's newer, larger, and higher capacity aircraft. An array of high amperage power contacts and conventional pin and socket relay contacts are used. One embodiment of the present invention is the receptacle connector housing having an extended shroud with boss like creepage barrier tubes and keyway to engage an envelope of plug connector housing having male boss and key. Specifically, boss like creepage barrier tubes and male boss are constructed to protect the high amperage power contacts. Another embodiment is the full mechanical coupling between the aircraft fixed receptacle connector and ground supply free plug connector as provided by having the latch pin in the plug connector in a locked position within the receptacle connector slide latch fastener.

Abstract: An aircraft ground power connector comprising: (a) a plurality of electrical contact pins embedded in an insulating housing having first and second layers of insulating material, wherein each pin has a male end and female end and is arranged in the housing so that the male ends are protruding from a male side of the connector, and the female ends of the pins (i) are recessed in a female side of the connector, (ii) have a shape, length, and diameter adapted to permit them to receive a male pin, (iii) have slots in the sides thereof; and the housing is a multi-layer assembly having at least two layers of insulating material arranged perpendicular to the direction of the pins; including (i) a first layer of insulating material positioned on the female side of the connector, wherein the first layer and the portion of the female end of the pins embedded therein are shaped to prevent the pin from being pushed out of the female side of the connector; and (ii) a second layer of insulating material positioned so that

Abstract: A connector assembly which enables conductive paths of a first body to be electrically connected to the conductive paths of a second body. The assembly comprising:at least two spigot members; anda connecting member having a cover member into which a resilient member and a displaceable member are assembled.Each of the members of the connecting member are provided with corresponding orifices that form a passageway which is shaped so that it can engage with a groove formed on a respective spigot member. In operation, the spigot members are inserted into a respective passageway and the connecting member moved relative thereto so that the groove and passageway co-operate with one another to clamp the first and second bodies together, and thereby effect electrical connection between the respective conductive paths.