Patents by Inventor David P. Hause

David P. Hause has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-hypertensive and cholesterol-lowering fixed-dose combination and method of manufacture
    Patent number: 11737988
    Abstract: Disclosed is a method of manufacturing a cardiovascular fixed-dose combination pharmaceutical dosage form that includes an anti-hypertensive active agent, a cholesterol-lowering active agent, and optionally, an enteric-coated aspirin or platelet inhibitor. The fixed-dose combination is prepared with at least two granulation solutions that are free of citric acid and enhance the aqueous solubility of the cholesterol-lowering agent in fixed-dose combination. The active agents in the resulting dosage form, which is also free of citric acid, have the same strength and release profiles as the same active agents prepared as a single formulation.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: August 29, 2023
    Assignee: CardioPharma, Inc.
    Inventors: Roy A. Stimits, Daniel Tyree Gregory, Jr., Wayne L. Whittingham, Stephan Dale Glenn, David P. Hause
  • ANTI-HYPERTENSIVE AND CHOLESTEROL-LOWERING FIXED-DOSE COMBINATION AND METHOD OF MANUFACTURE
    Publication number: 20200330391
    Abstract: Disclosed is a method of manufacturing a cardiovascular fixed-dose combination pharmaceutical dosage form that includes an anti-hypertensive active agent, a cholesterol-lowering active agent, and optionally, an enteric-coated aspirin or platelet inhibitor. The fixed-dose combination is prepared with at least two granulation solutions that are free of citric acid and enhance the aqueous solubility of the cholesterol-lowering agent in fixed-dose combination. The active agents in the resulting dosage form, which is also free of citric acid, have the same strength and release profiles as the same active agents prepared as a single formulation.
    Type: Application
    Filed: April 17, 2019
    Publication date: October 22, 2020
    Inventors: Roy A. Stimits, Daniel Tyree Gregory, JR., Wayne L. Whittingham, Stephan Dale Glenn, David P. Hause
  • PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF PAIN
    Publication number: 20090041839
    Abstract: The present invention provides pharmaceutical compositions comprising an allosteric adenosine A1 receptor enhancer, such as T-62, in an oral dosage form and processes for the manufacture of such compositions and dosage forms. In another aspect, the present invention relates to a method of employing such dosage forms for the treatment of pain, including acute pain, e.g., postoperative pain, chronic pain, inflammatory pain, neuropathic pain and pain associated with migraine.
    Type: Application
    Filed: May 22, 2008
    Publication date: February 12, 2009
    Inventors: Martin W. Beasley, David P. Hause, David J. Reynolds
  • Oral compositions of H.sub.2 -antagonists
    Patent number: 5538737
    Abstract: The present invention provides pharmaceutical capsule compositions for the oral administration of an H.sub.2 -antagonist. The composition includes a capsule containing an emulsion having a water portion and an oil portion. A pharmaceutically acceptable salt of an H.sub.2 -antagonist is dissolved in the water portion. The composition delivers a therapeutically effective amount of the H.sub.2 -antagonist to a patient in need thereof. The present invention also provides methods of making the capsule composition.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: July 23, 1996
    Assignee: Applied Analytical Industries, Inc.
    Inventors: Thomas W. Leonard, David P. Hause, Frederick D. Sancilio, James Swarbrick, Edward S. Wilson