Abstract: The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations. In some embodiments, analysis results are correlated with clinical outcome measures such as risk of bladder cancer recurrence.

Abstract: The present disclosure relates to viral vaccine formulations with enhanced stability and methods of use thereof.

Abstract: The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations. In some embodiments, analysis results are correlated with clinical outcome measures such as risk of bladder cancer recurrence.

Abstract: The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations. In some embodiments, analysis results are correlated with clinical outcome measures such as risk of bladder cancer recurrence.

Abstract: The present disclosure relates to viral vaccine formulations with enhanced stability and methods of use thereof.

Abstract: Systems and methods for reducing engine emissions in a locomotive are presented. In an embodiment, a fuel injector or a fuel injection pump of a fuel injection mechanism includes a plunger with an upper helix whose angle changes between points on the plunger that correspond to an idle throttle position and a full throttle position. As such, injection timing is optimized, and engine emissions are reduced.

Abstract: Systems and methods for reducing engine emissions in a locomotive are presented. In an embodiment, a fuel injector or a fuel injection pump of a fuel injection mechanism includes a plunger with an upper helix whose angle changes between points on the plunger that correspond to an idle throttle position and a full throttle position. As such, injection timing is optimized, and engine emissions are reduced.

Abstract: Systems and methods for reducing engine emissions in a locomotive are presented. In an embodiment, a fuel injector or a fuel injection pump of a fuel injection mechanism includes a plunger with an upper helix whose angle changes between points on the plunger that correspond to an idle throttle position and a full throttle position. As such, injection timing is optimized, and engine emissions are reduced.

Abstract: Systems and methods for reducing engine emissions in a locomotive are presented. In an embodiment, a fuel injector or a fuel injection pump of a fuel injection mechanism includes a plunger with an upper helix whose angle changes between points on the plunger that correspond to an idle throttle position and a full throttle position. As such, injection timing is optimized, and engine emissions are reduced.

Abstract: A one-piece toilet seat hinge composed of an elastomeric material throughout, and having the characteristics of rubber, and including a flat flange member and a coplanar support shank, the flange member being designed to be connected to the toilet seat and the support shank being generally cylindrical in shape and externally threaded to facilitate mounting thereof within a cavity normally found on the toilet stool for connection of the seat thereto. The flange member has lower peripheral portions having sufficient memory to cause the toilet seat to swing from a horizontal orientation, upon release, to a vertically extending orientation, thereby obviating the likelihood of the seat being soiled by a subsequent male urinator.

Abstract: A Sleeve Valve for regulating the water level in ponds, lagoons and other wetlands which includes an outer tubular section of plastic pipe with a plurality of vertically spaced openings and an inner tubular section of plastic pipe that is disposed telescopically within, and rotatable relative to, the outer tubular pipe. This inner tubular pipe includes a plurality of vertically spaced openings that are positionally staggered about a circumference and arranged for selective alignment with one of the openings in the outer pipe. Each of the openings in the outer pipe are sealed against the outer wall of the inner pipe until rotation of the inner pipe causes alignment of a selected opening in the outer pipe with a corresponding opening in the inner pipe, thereby allowing water to pass only through such corresponding aligned openings. The water level is regulated by selecting and aligning corresponding openings in the outer and inner pipes at the water level desired.

Abstract: A method for producing and using oak chips or other divided forms of the oak for aging wine is described. The chips or other divided forms are provided in a permeable container. In particular a method is described for removing undesirable flavors from the oak by soaking the oak in an aqueous solution of water or water and ethanol and toasting the oak to enhance desirable flavors prior to or after the soaking. The method produces wines which are comparable to the best barrel aged wines.