Patents by Inventor David P Speert

David P Speert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of dextran and other polysaccharides to improve mucus clearance
    Publication number: 20020032172
    Abstract: This invention relates to the use of polysaccharide such as dextran to improve mucus clearance. In the present invention, dextran has been shown to reduce viscoelasticity and increase mucus clearability of sputum of cystic fibrosis patients. Dextran also reduced viscoelasticity of healthy dog mucus. The present invention therefore may be used to improve mucus clearance in cystic fibrosis patients and treat other conditions associated with defect in airway mucus clearance including chronic bronchitis, bronchiectasis and bronchial asthma.
    Type: Application
    Filed: June 28, 2001
    Publication date: March 14, 2002
    Inventors: Malcolm King, David P. Speert
  • Use of dextran and other polysaccharides to improve mucus clearance
    Patent number: 6339075
    Abstract: This invention relates to the use of polysaccharide such as dextran to improve mucus clearance. In the present invention, dextran has been shown to reduce viscoelasticity and increase mucus clearability of sputum of cystic fibrosis patients. Dextran also reduced viscoelasticity of healthy dog mucus. The present invention therefore may be used to improve mucus clearance in cystic fibrosis patients and treat other conditions associated with defect in airway mucus clearance including chronic bronchitis, bronchiectasis and bronchial asthma.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: January 15, 2002
    Assignees: The University of British Columbia, The University of Alberta
    Inventors: Malcolm King, David P Speert
  • Method of preventing or reducing the risk of infection by bacterial pathogens utilizing simple and conjugated dextrans
    Patent number: 5514665
    Abstract: Methods for reducing the risk of or preventing infections by bacterial pathogens in vivo. In particular, a method for reducing the risk of P. aeruginosa infection in vivo in compromised hosts such as cystic fibrosis patients. The methods involve the use of dextran or dextran sulphate as the active ingredient.
    Type: Grant
    Filed: October 3, 1994
    Date of Patent: May 7, 1996
    Assignee: University of British Columbia
    Inventors: David P. Speert, Thomas C. Usher