Patents by Inventor David P. Summers

David P. Summers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10869842
    Abstract: A method of administering a pharmaceutical agent to the circulatory system through the skin of a mammal may include the steps of loading a pharmaceutical agent in a transdermal patch, applying the transdermal patch to the skin of the mammal and releasing the pharmaceutical agent into the circulatory system at a rate of at least 0.001 micrograms per hour up to 50.0 micrograms per hour per kilogram of bodyweight of the mammal. The drug delivery system may comprise a transdermal patch loaded with the pharmaceutical agent. The patch may include a porous membrane and an outer impermeable cover defining a cavity therebetween. A plurality of drug delivery layers may be disposed between the porous membrane and the impermeable cover. A lipophilic/hydrophilic suspension may be disposed between the drug delivery layers.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: December 22, 2020
    Inventor: David P Summers
  • Patent number: 9962393
    Abstract: In a multilamellar liposome, a pharmaceutical agent is encapsulated in the liposome in the absence of a partition enhancing buffer. Preferably, the pharmaceutical agent is prostaglandin E1 (PGE1). The pharmaceutical agent may be administered to a mammal in an amount effective to treat vascular disease. The release of the pharmaceutical agent from the multilamellar liposome may be regulated by proper selection of liposome size, dosage of the pharmaceutical agent, lipid to pharmaceutical agent weight ratio, and rate of infusion of the pharmaceutical agent.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: May 8, 2018
    Inventor: David P Summers
  • Patent number: 7074812
    Abstract: In a method of developing muscle mass in a mammal, nicotine or nicotine acetylcholine receptor agonist (nAChR) is administered in combination with exercise to stimulate, recruit and mobilize muscle cells to a specific muscle mass.
    Type: Grant
    Filed: August 2, 2003
    Date of Patent: July 11, 2006
    Assignee: Nutraleutical Development Corporation
    Inventors: David P. Summers, James Davidson
  • Publication number: 20040167179
    Abstract: In a method of developing muscle mass in a mammal, nicotine or nicotine acetylcholine receptor agonist (nAChR) is administered in combination with exercise to stimulate, recruit and mobilize muscle cells to a specific muscle mass.
    Type: Application
    Filed: August 2, 2003
    Publication date: August 26, 2004
    Inventors: David P. Summers, James Davidson
  • Publication number: 20040106988
    Abstract: A resorbable, biodegradable, drug delivery prosthesis (10) includes mechanical properties for maintaining the strength needed to acutely open and maintain a vessel, duct, tract, or organ, and precise chronicity for controlling the release and delivery of drugs or biologic agents. The drugs and biologic agents are capable of acting upon and altering the mechanisms of biologic systems in an manner providing a medicinal therapy. The method of the invention includes a one step process of extruding the admixture forming the prosthesis (10) into a geometry compatible with its use.
    Type: Application
    Filed: March 28, 2003
    Publication date: June 3, 2004
    Inventor: David P. Summers
  • Patent number: 6395023
    Abstract: A prosthesis for replacing or strengthening a particular part of the body is coated with a biodegradable, resorbable and biocompatible surface coating. Biologically active microspheres which controllably release the biologically active agents are embedded in the surface coating. The biologically active microspheres include encapsulated PGE1 in a polyethylene glycol mix, which over a period of time dissolves and releases the PGE1 into the body part.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: May 28, 2002
    Assignee: Endovasc Ltd., Inc.
    Inventor: David P. Summers
  • Patent number: 5980551
    Abstract: A stent or vascular graft for supporting a blood vessel or organ lumen is coated with a biodegradable, resorbable and hemocompatible surface substrate. Biologically active microspheres which controllably release the biologically active agent into the vessel wall or organ to inhibit restenosis of the stent is embedded in the stent substrate. The biologically active microspheres include encapsulated PGE1 in a water soluble polyethylene glycol mix, which over a period of time dissolves and releases the PGE1 into the vessel wall or organ.
    Type: Grant
    Filed: February 7, 1997
    Date of Patent: November 9, 1999
    Assignee: Endovasc Ltd., Inc.
    Inventors: David P. Summers, Jackie R. See
  • Patent number: 5728129
    Abstract: A distal atherectomy catheter is disclosed for removing obstructions, plaque, stenosis, occlusions, or the like from an artery or coronary vessel. The catheter comprises a flexible, hollow catheter tube. A cutting element is located within a cylindrical housing mounted at the distal end of the catheter tube. The cutting element is connected to a hollow, flexible drive shaft concentrically located within the catheter tube. The cutting element housing includes a side opening window or port providing access to the interior of the housing. An idler shaft journaled about the drive shaft provides a non-rotating surface adjacent the cutting element. An annular return passage is defined between the catheter tube and the flexible drive shaft providing a discharge passage communicating with external aspirating means for collection of cuttings removed by the cutting element from the artery or coronary vessel.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 17, 1998
    Assignee: American Biomed, Inc.
    Inventor: David P. Summers
  • Patent number: 5695519
    Abstract: A distal intravascular filter is disclosed for filtering blood flow therethrough and entrapping and retaining embolic debris. The intravascular filter including a small diameter hollow guide wire or tube capable of percutaneous placement of the distal end thereof beyond a carotid stenosis. The distal portion of the tube includes a filter mounted thereon. The filter is deployable from a tightly closed configuration to an open circumference for blocking the unfiltered flow of blood beyond the carotid stenosis. The filter is deployable between open and closed positions by manipulation of an actuating wire extending from the filter and out the proximal end of the tube.
    Type: Grant
    Filed: November 30, 1995
    Date of Patent: December 9, 1997
    Assignee: American Biomed, Inc.
    Inventors: David P. Summers, Gary Ball
  • Patent number: 5607445
    Abstract: A stent comprising a coil including a plurality of arcuate sections that alternate directions around a central axis, each arcuate section including a pair of curved turns joined by a cusp, and the cusps of adjacent arcuate sections intermeshing and defining at least one region of overlap, which in turn describes a helix around and along the length of the coil. In the preferred embodiment, there are two regions of overlap, which together describe a double helix. In another preferred embodiment, the stent is bifurcated so as to support a branched vessel or the like.A method for forming a stent, including the steps of providing a flat sheet of material, chemically etching said sheet to form a blank, and forming said blank into a cylindrical coil. The coiling step is preferably carried out on a plurality of rollers.
    Type: Grant
    Filed: December 16, 1994
    Date of Patent: March 4, 1997
    Assignee: American BioMed, Inc.
    Inventor: David P. Summers
  • Patent number: 5458573
    Abstract: The present invention is directed to a toposcopic dilatation catheter system utilizing a dilatation balloon in combination with an everting tube in a miniature catheter of a scale sufficiently small to negotiate a blood vessel for therapeutic as well as diagnostic purposes. The catheter system utilizes a primary catheter shaft provided with multiple lumen or passageways extending the length thereof. The dilatation balloon lumen provides access to a balloon carried at the distal end of the primary catheter shaft. The dilatation balloon may be expanded as required to aid in advancing the catheter system to the site requiring therapy. A secondary catheter tube is coaxially carried within the primary catheter shaft. The leading end of the secondary catheter tube includes an everting tube which everts from the leading end of the primary catheter shaft. The everting tube advances under fluid pressure in advance to the leading end of the primary catheter shaft.
    Type: Grant
    Filed: May 1, 1992
    Date of Patent: October 17, 1995
    Assignee: American BioMed, Inc.
    Inventor: David P. Summers
  • Patent number: 5431673
    Abstract: A distal atherectomy catheter is disclosed for removing obstructions, plaque, stenosis, occlusions, or the like from an artery or coronary vessel. The catheter comprises a flexible, hollow catheter tube. A reciprocating, and rotating or oscillating cutting element is located within a cylindrical housing mounted at the distal end of the catheter tube. The cutting element is connected to a hollow, flexible drive shaft concentrically located within the catheter tube. The cutting element housing includes a side opening window or port providing access to the interior of the housing. An idler shaft journaled about the drive shaft provides a non-rotating surface adjacent the cutting element. An annular return passage is defined between the catheter tube and the flexible drive shaft providing a discharge passage communicating with external aspirating means for collection of cuttings removed by the cutting element from the artery or coronary vessel.
    Type: Grant
    Filed: June 8, 1992
    Date of Patent: July 11, 1995
    Assignee: American BioMed, Inc.
    Inventors: David P. Summers, Gail L. Brinson
  • Patent number: 5383884
    Abstract: The surgical instrument of the present invention includes a cannula shaft terminating in a cutting window at the distal end of the cannula shaft. The proximal end of the cannula shaft is supported by a handle having an axial bore extending therethrough. A flexible drive shaft, connected at one end to an external drive mechanism, extends through the handle and the cannula shaft. A cutting head is mounted to the distal end of the drive shaft and positioned for cooperative cutting action with the cutting window of the cannula shaft. A non-rotating idler shaft is journaled about the drive shaft. Severed tissue is removed or evacuated from the surgical site through an annular passage formed by the cannula and idler shafts.
    Type: Grant
    Filed: December 4, 1992
    Date of Patent: January 24, 1995
    Assignee: American BioMed, Inc.
    Inventor: David P. Summers
  • Patent number: 5370651
    Abstract: This disclosure sets out a catheter for bodily insertion. The catheter tip supports an elongate hollow housing with a window for occlusive material cutting, a cutter head on the interior rotates, driven by a drive wire in the hollow catheter tube. In addition, the cutter head reciprocates or oscillates to cut on its back edge, the edge trimming material entering through the window. The window and optional slots admit the unwanted material and enable trimming for a vacuum removal through the catheter tube. The window is urged into contact by a pair of flexed wires, the wires moving the housing into operative contact.
    Type: Grant
    Filed: February 10, 1992
    Date of Patent: December 6, 1994
    Inventor: David P. Summers
  • Patent number: 5342387
    Abstract: A stent comprising a coil including a plurality of arcuate sections that alternate directions around a central axis, each arcuate section including a pair of curved turns joined by a cusp, and the cusps of adjacent arcuate sections intermeshing and defining at least one region of overlap, which in turn describes a helix around and along the length of the coil. In the preferred embodiment, there are two regions of overlap, which together describe a double helix. In another preferred embodiment, the stent is bifurcated so as to support a branched vessel or the like.
    Type: Grant
    Filed: June 18, 1992
    Date of Patent: August 30, 1994
    Assignee: American BioMed, Inc.
    Inventor: David P. Summers
  • Patent number: 5112292
    Abstract: A temporary circulatory assist pump is disclosed for implantation in the heart of a patient through the femoral artery. The pump is driven by a flexible drive shaft extending through a catheter and being connected to a power source outside the body of the patient. The pump utilizes a helical-shaped foil impeller to pump blood at a rate of approximately three to four liters per minute through the circulatory system of the patient.
    Type: Grant
    Filed: October 25, 1990
    Date of Patent: May 12, 1992
    Assignee: American Biomed, Inc.
    Inventors: Ned H. C. Hwang, David P. Summers
  • Patent number: 5112349
    Abstract: A temporary circulatory assist pump is disclosed for implantation in the heart of a patient through the femoral artery. The pump is driven by a flexible drive shaft extending through a catheter and being connected to a power source outside the body of the patient. The pump utilizes the moineau pumping principal to pump blood at a rate of approximately three to four liters per minute through the circulatory system of the patient.
    Type: Grant
    Filed: October 22, 1990
    Date of Patent: May 12, 1992
    Assignee: American BioMed, Inc.
    Inventors: David P. Summers, Jeddy D. Nixon
  • Patent number: 5087265
    Abstract: This disclosure sets out a catheter for bodily insertion. The catheter tip supports an elongate hollow housing with a window for occlusive material cutting, a cutter head on the interior rotates, driven by a drive wire in the hollow catheter tube. In addition, the cutter head reciprocates or oscillates to cut on its back edge, the edge trimming material entering through the window. The window and optional slots admit the unwanted material and enable trimming for a vacuum removal through the catheter tube. The window is urged into contact by a pair of flexed wires, the wires moving the housing into operative contact.
    Type: Grant
    Filed: July 24, 1989
    Date of Patent: February 11, 1992
    Assignee: American BioMed, Inc.
    Inventor: David P. Summers
  • Patent number: 4994067
    Abstract: A distal atherectomy catheter comprises a flexible outer catheter tube housing a reciprocal cutting element at its distal end. The cutting element is connected to an inner catheter tube concentrically located within the outer catheter tube. An annular passage defined between the inner and outer tubes provides a discharge passage communicating with an external vacuum mechanism for collection of excised material removed from the coronary vessel. A flexible drive shaft extending through the inner catheter tube terminates in a detachable cutting burr for boring through obstructions in the coronary vessel. The drive cable is connected to an external drive motor.
    Type: Grant
    Filed: February 17, 1989
    Date of Patent: February 19, 1991
    Assignee: American Biomed, Inc.
    Inventor: David P. Summers
  • Patent number: 4969865
    Abstract: A temporary circulatory assist pump is disclosed for implantation in the heart of a patient through the femoral artery. The pump is driven by a flexible drive shaft extending through a catheter and being connected to a power source outside the body of the patient. The pump utilizes a helical-shaped foil impeller to pump blood at a rate of approximately three to four liters per minute through the circulatory system of the patient.
    Type: Grant
    Filed: January 9, 1989
    Date of Patent: November 13, 1990
    Assignee: American Biomed, Inc.
    Inventors: Ned H. C. Hwang, David P. Summers