Patents by Inventor David Panikashvili

David Panikashvili has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-arachidonylglycerol (2-AG)-an inhibitor of tumor necrosis factor-&agr; and neuroprotector of brain in closed head injury
    Patent number: 6566543
    Abstract: The present invention relates to 2-arachidonylglycerol (2-AG) to be used as inhibitor of a tumor necrosis factor (TNF-&agr;), in the reduction of edema caused by closed head injury, in the reduction of neurological deficits caused by closed head injury and stroke and in treating pathological conditions caused by TNF-&agr; and/or by radical oxygen intermediates (ROI), in pharmaceutical composition for the same use comprising as active ingredient 2-AG. It comprises also the use of 2-AG and pharmaceutical compositions comprising same in the preparation of a medicament for the treatment of said indications and methods of treatment by 2-AG and pharmaceutical compositions comprising same for diseases caused by said indications.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: May 20, 2003
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem
    Inventors: Raphael Mechoulam, Ruth Gallily, Aviva Breuer, Esther Shohami, David Panikashvili
  • 2-Arachidonylglycerol (2-AG)-an inhibitor of tumor necrosis factor-alpha and neuroprotector of brain in closed head injury
    Publication number: 20020072539
    Abstract: The present invention relates to 2-arachidonylglycerol (2-AG) to be used as inhibitor of a tumor necrosis factor (TNF-&agr;), in the reduction of edema caused by closed head injury, in the reduction of neurological deficits caused by closed head injury and stroke and in treating pathological conditions caused by TNF-&agr; and/or by radical oxygen intermediates (ROI), in pharmaceutical composition for the same use comprising as active ingredient 2-AG. It comprises also the use of 2-AG and pharmaceutical compositions comprising same in the preparation of a medicament for the treatment of said indications and methods of treatment by 2-AG and pharmaceutical compositions comprising same for diseases caused by said indications.
    Type: Application
    Filed: June 22, 2001
    Publication date: June 13, 2002
    Inventors: Raphael Mechoulam, Ruth Gallily, Aviva Breuer, Esther Shohami, David Panikashvili