Patents by Inventor David Patrick Knox

David Patrick Knox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant DNA molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections
    Publication number: 20080145379
    Abstract: The present invention provides nucleic acid molecules containing nucleotide sequences encoding helminth aminopeptidase enzymes, and antigenic fragments and functionally-equivalent variants thereof, their use in the preparation of vaccines, for use against helminth parasites, and synthetic polypeptides encoded by them.
    Type: Application
    Filed: November 2, 2006
    Publication date: June 19, 2008
    Applicant: The Agricultural and Food Research Council
    Inventors: Margaret Graham, Trevor Stanley Smith, Edward Albert Munn, David Patrick Knox, Joanna Jane Oliver, Susan Elizabeth Newton
  • Vaccines against helminthic parasites
    Publication number: 20030129204
    Abstract: The present invention provides a protective helminth parasite antigen obtainable from adult helminths characterized by: (I) in native form being an integral membrane protein; (ii) having a native localization in the parasite gut; (iii) being capable of binding to a thiol affinity medium; and (iv) being recognized by sera from immunized animal hosts, containing antibodies capable of inhibiting parasite growth and/or development, or a functionally-equivalent variant, or antigenic fragment or precursor thereof, its preparation from adult helminths, its use in vaccine compositions, DNA sequences encoding it and its production by recombinant means.
    Type: Application
    Filed: June 7, 2002
    Publication date: July 10, 2003
    Applicant: Moredun Scientific Limited
    Inventors: David Patrick Knox, Stuart Kevin Smith, William David Smith, Diane Redmond, Jacqueline Murray
  • Recombinant DNA molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections
    Publication number: 20030078398
    Abstract: The present invention provides nucleic acid molecules containing nucleotide sequences encoding helminth aminopeptidase enzymes, and antigenic fragments and functionally-equivalent variants thereof, their use in the preparation of vaccines, for use against helminth parasites, and synthetic polypetides encoded by them.
    Type: Application
    Filed: March 19, 2002
    Publication date: April 24, 2003
    Inventors: Margaret Graham, Trevor Stanley Smith, Edward Albert Munn, David Patrick Knox, Joanna Jane Oliver, Susan Elizabeth Newton
  • Recombinant DNA molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections
    Patent number: 6534638
    Abstract: The present invention provides nucleic acid molecules containing nucleotide sequences encoding helminth aminopeptidase enzymes, and antigenic fragments and functionally-equivalent variants thereof, their use in the preparation of vaccines for use against helminth parasites, and synthetic polypeptides encoded by them.
    Type: Grant
    Filed: August 5, 1998
    Date of Patent: March 18, 2003
    Assignee: Barbraham Institute
    Inventors: Margaret Graham, Trevor Stanley Smith, Edward Albert Munn, David Patrick Knox, Joanna Jane Oliver, Susan Elizabeth Newton
  • Recombinant DNA molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections
    Patent number: 6066503
    Abstract: The present invention provides nucleic acid molecules containing nucleotide sequences encoding helminth aminopeptidase enzymes, and antigenic fragments and functionally-equivalent variants thereof, their use in the preparation of vaccines for use against helminth parasites, and synthetic polypeptides encoded by them.
    Type: Grant
    Filed: January 9, 1995
    Date of Patent: May 23, 2000
    Assignee: Barbraham Institute
    Inventors: Margaret Graham, Trevor Stanley Smith, Edward Albert Munn, David Patrick Knox, Joanna Jane Oliver, Susan Elizabeth Newton