Abstract: Disclosed are compositions comprising a first lipid-conjugated oligonucleotide comprising a first lipid moiety, a first hybridization region, and a first primer region; a second lipid-conjugated oligonucleotide comprising a second hybridization region and a second lipid moiety, wherein the second hybridization region is the reverse complement of the first hybridization region; and a third oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region; compositions comprising a lipid-conjugated DNA oligonucleotide comprising a lipid moiety, a barcode region, and a capture sequence; and composition comprising a first lipid-conjugated DNA oligonucleotide comprising a lipid moiety and a first primer region; and a second DNA oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region

Abstract: Disclosed systems and methods herein provide for high bandwidth processing using a plurality of compute-memory chiplets. A computing package may be configured with a plurality of the compute-memory chiplets in order to perform processing operations in connection with a large language model. The compute-memory chiplets may be configured to operate using small, low-power computing dies that can efficiently operate for workloads with low arithmetic intensity.

Abstract: Provided are a method and system for readout error mitigation, the method comprising: obtaining, with a quantum computing system, a phase value representing a tetrahedral group or supergroup; applying to a qubit, with the quantum computing system, a signal corresponding to the phase value representing an element sampled from the tetrahedral group or supergroup; measuring, with the quantum computing system, an output of the qubit after applying the signal; determining, with the quantum computing system, a full specification of an error channel for the qubit based on selected group operations and the measured outputs, the error channel being specifiable based on the tetrahedral group or supergroup; and calculating, with the quantum computing system, a correction based on the determined error channel specification, for a further readout measurement result of the qubit to produce an error mitigated readout result for the qubit.

Abstract: Disclosed are compositions comprising a first lipid-conjugated oligonucleotide comprising a first lipid moiety, a first hybridization region, and a first primer region; a second lipid-conjugated oligonucleotide comprising a second hybridization region and a second lipid moiety, wherein the second hybridization region is the reverse complement of the first hybridization region; and a third oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region; compositions comprising a lipid-conjugated DNA oligonucleotide comprising a lipid moiety, a barcode region, and a capture sequence; and composition comprising a first lipid-conjugated DNA oligonucleotide comprising a lipid moiety and a first primer region; and a second DNA oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region

Abstract: A method is described that includes executing a convolutional neural network layer on an image processor having an array of execution lanes and a two-dimensional shift register. The two-dimensional shift register provides local respective register space for the execution lanes. The executing of the convolutional neural network includes loading a plane of image data of a three-dimensional block of image data into the two-dimensional shift register.

Abstract: A dual mode method of assessing a toll fee by collecting i) sensor data of a vehicle as it travels on a lane and determining a first axle count based on said sensor data; and 2) collecting video images of said vehicle and determining a second axle count based on said video images. The video images are analyzed using computer vision and machine learning to determine the second axle count, and the first and second axles count compared and if identical the vehicle is charged based on the axle count. However, the video images are re-analyzed if the first and second axle counts are not identical and this is repeated until identity is obtained. The system learns from its errors, and the axle count improves with time. If identity is not reached, the transaction record can be flagged for human intervention, but tests show at least 100 fold reduction in errors, thus obviating thousands of interventions per day. Ultimately, monthly summaries of charges are compiled and sent to the customer.

Abstract: An aerial vehicle with a plurality of selectively collapsible arms capable of transitioning between an extended state and a contracted state is described. In the extended position, the distance between the main body of the vehicle and the rotor associated with each arm is maximized. In the contracted state, the distance between the main body of the vehicle and the rotor associated with each arm is minimized. In certain embodiments, each of the arms may include one or more tape springs that are biased to selectively move the associated one or more rotors of each arm between the retracted and extended states.

Abstract: A coupling system for quickly connecting fluid conveying conduits.

Abstract: The disclosure generally relates to methods and applications of single-cell barcoding and methods of nucleotide sequencing using composition comprising lipid-modified oligonucleotides.

Abstract: The invention provides a method of treating cancer in a subject in need thereof, comprising administering to the subject: (a) a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein R is hydrogen or an acyl group; and (b) a PD-1 signaling inhibitor; wherein the compound of Formula I or pharmaceutically acceptable salt thereof and the PD-1 signaling inhibitor are administered in amounts which in combination are therapeutically effective. The invention further provides a pharmaceutical composition comprising a compound of Formula I or a pharmaceutically acceptable salt thereof, a PD-1 signaling inhibitor and a pharmaceutically acceptable carrier or excipient.

Abstract: The invention provides a method of treating cancer in a subject in need thereof, comprising administering to the subject: (a) a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein R is hydrogen or an acyl group; and (b) a PD-1 signaling inhibitor; wherein the compound of Formula I or pharmaceutically acceptable salt thereof and the PD-1 signaling inhibitor are administered in amounts which in combination are therapeutically effective. The invention further provides a pharmaceutical composition comprising a compound of Formula I or a pharmaceutically acceptable salt thereof, a PD-1 signaling inhibitor and a pharmaceutically acceptable carrier or excipient.

Abstract: The present invention provides assistance to a user that is on-boarding an action for a virtual assistant. Methods and systems provide, based on an initial command group, recommendations for additional commands, actions, and applications that are relevant to commands included in the initial command group. The initial command group includes commands that include a sequence of natural language words or tokens. Additional commands are determined. The additional commands are relevant to the initial commands and provided to the user as recommended commands to include in the command group. The additional commands are determined by employing the initial commands as search queries to search preprocessed document clusters. Each document included in the document clusters relates to a potential command to include in the command group. In response to receiving a selection of a recommended command, the command group is updated to include the selected recommended command.

Abstract: Disclosed are compositions comprising a first lipid-conjugated oligonucleotide comprising a first lipid moiety, a first hybridization region, and a first primer region; a second lipid-conjugated oligonucleotide comprising a second hybridization region and a second lipid moiety, wherein the second hybridization region is the reverse complement of the first hybridization region; and a third oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region; compositions comprising a lipid-conjugated DNA oligonucleotide comprising a lipid moiety, a barcode region, and a capture sequence; and composition comprising a first lipid-conjugated DNA oligonucleotide comprising a lipid moiety and a first primer region; and a second DNA oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region

Abstract: A method is described that includes, on an image processor having a two dimensional execution lane array and a two dimensional shift register array, repeatedly shifting first content of multiple rows or columns of the two dimensional shift register array and repeatedly executing at least one instruction between shifts that operates on the shifted first content and/or second content that is resident in respective locations of the two dimensional shift register array that the shifted first content has been shifted into.

Abstract: An aerial vehicle with a plurality of selectively collapsible arms capable of transitioning between an extended state and a contracted state is described. In the extended position, the distance between the main body of the vehicle and the rotor associated with each arm is maximized. In the contracted state, the distance between the main body of the vehicle and the rotor associated with each arm is minimized. In certain embodiments, each of the arms may include one or more tape springs that are biased to selectively move the associated one or more rotors of each arm between the retracted and extended states.

Abstract: An apparatus is described. The apparatus includes an execution lane array coupled to a two dimensional shift register array structure. Locations in the execution lane array are coupled to same locations in the two-dimensional shift register array structure such that different execution lanes have different dedicated registers.

Abstract: Systems, methods, and non-transitory computer-readable storage media are provided for crowdsourcing actions and commands of a digital assistant application, irrespective of the languages spoken by users of the digital assistant application. Techniques described herein enable the on-boarding of actions datasets, which include defined commands and actions that result therefrom, from client devices to a remote server device. More specifically, the described techniques facilitate the proper on-boarding, distribution, and retrieval of action datasets regardless of the command language employed by users of the digital assistant application to invoke a properly-determined corresponding action.

Abstract: A coupling system for quickly connecting fluid conveying conduits.

Abstract: The present invention provides assistance to a user that is on-boarding an action for a virtual assistant. Methods and systems provide, based on an initial command group, recommendations for additional commands, actions, and applications that are relevant to commands included in the initial command group. The initial command group includes commands that include a sequence of natural language words or tokens. Additional commands are determined. The additional commands are relevant to the initial commands and provided to the user as recommended commands to include in the command group. The additional commands are determined by employing the initial commands as search queries to search preprocessed document clusters. Each document included in the document clusters relates to a potential command to include in the command group. In response to receiving a selection of a recommended command, the command group is updated to include the selected recommended command.