Abstract: The present disclosure relates to protein molecules that specifically bind to CD123, which may have at least one humanized or human CD123-binding domain. Such molecules are useful for the treatment of cancer. The protein molecule binding to CD123 may have a second binding domain that binds to another target. In one embodiment, multi-specific polypeptide molecules bind both CD123-expressing cells and the T-cell receptor complex on T-cells to induce target-dependent T-cell cytotoxicity, activation, and proliferation. The disclosure also provides pharmaceutical compositions comprising the CD123-binding polypeptide molecules, nucleic acid molecules encoding these polypeptides and methods of making these molecules.

Abstract: Electrical switch assemblies are described which include multiple switch bars. Each switch bar provides both physical and electrical separation between adjacent electrical components. Also, described are battery powered devices using the switch assemblies. Examples of devices using the switch assemblies include flashlights and remote control devices. The devices and switch assemblies avoid parasitic battery drain.

Abstract: A strainer adapted for releasable engagement with an open top of a can or container is described. The strainer includes an open ring member and a spout integrally formed therewith. Also described is a strainer system using the strainer and a mesh material. Various methods of use are also described.

Abstract: A control system for a machine with a rotatable operator station includes sensors to produce data indicative of suitability and unsuitability of the machine for initiating and completing adjustment, respectively, between a first control configuration where the operator station is at a first orientation and a second control configuration where the operator station is at a second orientation. A control device in the control system transitions the control system between a locking state for inhibiting rotation of the operator station and an unlocking state for permitting rotation, based on the suitability data and the unsuitability data.

Abstract: A control system for a machine with a rotatable operator station includes sensors to produce data indicative of suitability and unsuitability of the machine for initiating and completing adjustment, respectively, between a first control configuration where the operator station is at a first orientation and a second control configuration where the operator station is at a second orientation. A control device in the control system transitions the control system between a locking state for inhibiting rotation of the operator station and an unlocking state for permitting rotation, based on the suitability data and the unsuitability data.

Abstract: Electrical switch assemblies are described which include multiple switch bars. Each switch bar provides both physical and electrical separation between adjacent electrical components. Also, described are battery powered devices using the switch assemblies. Examples of devices using the switch assemblies include flashlights and remote control devices. The devices and switch assemblies avoid parasitic battery drain.