Patents by Inventor David Peretz

David Peretz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10527614
    Abstract: The present disclosure provides methods and kits for detecting analytes using avidin-biotin assays.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: January 7, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventor: David Peretz
  • Publication number: 20190254834
    Abstract: The present invention relates generally to a prosthetic spinal disc for replacing a damaged disc between two vertebrae of a spine and methods for inserting said discs. The intervertebral prosthetic discs are provided with connections for facilitating implantation and removal and features which enhance primary and secondary stability over time.
    Type: Application
    Filed: May 2, 2019
    Publication date: August 22, 2019
    Inventors: Anand Balasubramanian, Edward Dwyer, David Peretz, David W. Ankney, William Rhoda, David C. Paul, Christopher Angelucci
  • Publication number: 20190247094
    Abstract: Orthopedic fixation devices and methods of installing the same. The orthopedic fixation device may include a coupling element and a bone fastener, whereby the bone fastener can be loaded into the coupling element through the bottom of a bore in the coupling element.
    Type: Application
    Filed: April 26, 2019
    Publication date: August 15, 2019
    Inventors: George Yacoub, Jeff Nichols, David Peretz, Caelan Allen
  • Patent number: 10314716
    Abstract: The present invention relates generally to a prosthetic spinal disc for replacing a damaged disc between two vertebrae of a spine and methods for inserting said discs. The intervertebral prosthetic discs are provided with connections for facilitating implantation and removal and features which enhance primary and secondary stability over time.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: June 11, 2019
    Assignee: Globus Medical, Inc.
    Inventors: Anand Balasubramanian, Edward J. Dwyer, David Peretz, David W. Ankney, William Rhoda, David C. Paul, Christopher Angelucci
  • Publication number: 20180064550
    Abstract: The present invention relates generally to a prosthetic spinal disc for replacing a damaged disc between two vertebrae of a spine and methods for inserting said discs. The intervertebral prosthetic discs are provided with connections for facilitating implantation and removal and features which enhance primary and secondary stability over time.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 8, 2018
    Inventors: Anand Balasubramanian, Edward J. Dwyer, David Peretz, David W. Ankney, William Rhoda, David C. Paul, Christopher Angelucci
  • Patent number: 9844442
    Abstract: The present invention relates generally to a prosthetic spinal disc for replacing a damaged disc between two vertebrae of a spine and methods for inserting said discs. The intervertebral prosthetic discs are provided with connections for facilitating implantation and removal and features which enhance primary and secondary stability over time.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: December 19, 2017
    Assignee: GLOBUS MEDICAL, INC.
    Inventors: Anand Balasubramanian, Ed Dwyer, David Peretz, David Ankney, William S Rhoda, David C Paul, Christopher Angelucci
  • Publication number: 20170131269
    Abstract: The present disclosure provides methods and kits for detecting analytes using avidin-biotin assays.
    Type: Application
    Filed: November 8, 2016
    Publication date: May 11, 2017
    Inventor: DAVID PERETZ
  • Publication number: 20140296985
    Abstract: The present invention relates generally to a prosthetic spinal disc for replacing a damaged disc between two vertebrae of a spine and methods for inserting said discs. The intervertebral prosthetic discs are provided with connections for facilitating implantation and removal and features which enhance primary and secondary stability over time.
    Type: Application
    Filed: June 12, 2014
    Publication date: October 2, 2014
    Inventors: Anand Balasubramanian, Ed Dwyer, David Peretz, David Ankney, William S Rhoda, David C Paul, Christopher Angelucci
  • Patent number: 8844304
    Abstract: A pool heating system is disclosed. The pool heating system includes, in some embodiments, an immersed condenser coil. In some embodiments, the immersed condenser coil is immersed in a pool of water receiving hot refrigerant gas at high pressure from an outdoor unit, transferring heat to water in the pool, condensing the gas and transmitting condensed refrigerant to the outdoor unit. The system also includes an outdoor unit. In some embodiments, the outdoor unit includes a compressor, an expansion valve, an evaporator, and a fan.
    Type: Grant
    Filed: May 11, 2011
    Date of Patent: September 30, 2014
    Inventor: David Peretz
  • Publication number: 20130273573
    Abstract: The invention provides methods for assessing increased probability of having Alzheimer's disease in a subject under assessment including a step of obtaining a measurement of A?40 aggregates in a biological sample from the subject, where the biological sample does not include brain tissue, a fraction of brain tissue, or brain homogenate. In some embodiments, the invention relates to methods of assessing increased probability of early stage Alzheimer's disease. The invention further provides methods of assessing increased probability of not having Alzheimer's disease, methods of monitoring disease progression in a subject with Alzheimer's disease, and methods of assigning disease stage for a subject with Alzheimer's disease, and methods of assessing increased probability of MCI progressing to Alzheimer's disease.
    Type: Application
    Filed: November 30, 2010
    Publication date: October 17, 2013
    Applicant: NOVARTIS AG
    Inventors: Sophie Allauzen, Joseph Fedynyshyn, David Peretz, Xuemei Wang, Alice Yam
  • Publication number: 20130109581
    Abstract: The invention provides methods for detecting the presence of an aggregate in a sample by contacting the sample suspected of containing an aggregate with an aggregate-specific binding reagent under conditions that allow the binding of the reagent to the aggregate, if present; and detecting the presence of the aggregate, if any, in the sample by its binding to the reagent; where the aggregate-specific binding reagent typically has a net charge of at least about positive one at the pH at which the sample is contacted with the ASB reagent, is attached to a solid support at a charge density of at least about 60 nmol net charge per square meter, and binds preferentially with aggregates over monomers when attached to the solid support. Methods for detecting the presence of oligomer are also provided. Compositions for use in the methods are provided.
    Type: Application
    Filed: November 4, 2010
    Publication date: May 2, 2013
    Inventors: David Peretz, Alice Yam, Xuemei Wang, Man Gao
  • Publication number: 20120065774
    Abstract: One embodiment of the present invention relates to a semi-automated apparatus for vending granular materials in a container comprising a cabinet with a carousel capable of rotating and housing at least one dispensing container. Each dispensing container is adapted to hold granular material and in one embodiment includes a pressure actuated valve. A pneumatic system is coupled to each of the dispensing containers. A motor is coupled to the carousel. The apparatus further comprises a loading station adapted to hold the container, a control system and a user control panel having at least one user interface for controlling operation of the vending machine. The control system, coupled to the motor, the pneumatic system and the user control panel, engages the motor, causing the carousel to rotate, and the pneumatic system, pressurizing the selected dispensing container causing a predetermined amount of granular material to dispense into the vending container.
    Type: Application
    Filed: September 14, 2010
    Publication date: March 15, 2012
    Inventor: David Peretz
  • Publication number: 20120027677
    Abstract: The invention relates to peptoid reagents that interact preferentially with a pathogenic form of a conformational disease protein as compared to a nonpathogenic form of the conformational disease protein where the peptoid reagent comprises an amino-terminal region, a carboxy-terminal region, and at least one peptoid region between the amino-terminal region and the carboxy-terminal region where the peptoid region comprises 3 to about 30 N-substituted glycines, and optionally one or more amino acids. The invention also relates to methods of using the peptoids in detecting and isolating prions, and in the treatment and prevention of prion-related diseases.
    Type: Application
    Filed: October 7, 2010
    Publication date: February 2, 2012
    Inventors: David Peretz, Michael D. Connolly, Ronald Zuckermann, Man Gao, Gulliver Timoteo, Robert M. Shimizu
  • Publication number: 20110277488
    Abstract: A pool heating system is disclosed. The pool heating system includes, in some embodiments, an immersed condenser coil. In some embodiments, the immersed condenser coil is immersed in pool of water receiving hot refrigerant gas at high pressure from an outdoor unit, transferring heat to water in the pool, condensing the gas and transmitting condensed refrigerant to the outdoor unit. The system also includes an outdoor unit. In some embodiments, the outdoor unit includes a compressor, an expansion valve, an evaporator, and a fan.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Inventor: David Peretz
  • Publication number: 20110189692
    Abstract: The invention provides methods for detecting the presence of a non-prion pathogenic conformer in a sample by contacting the sample suspected of containing a non-prion pathogenic conformer with a pathogenic conformer-specific binding reagent under conditions that allow the binding of the reagent to the pathogenic conformer, if present; and detecting the presence the pathogenic conformer, if any, in the sample by its binding to the reagent; where the pathogenic conformer-specific binding reagent is typically derived from a prion protein fragment and interacts preferentially with a pathogenic prion protein. Methods for diagnosis of conformational diseases are also provided.
    Type: Application
    Filed: April 29, 2009
    Publication date: August 4, 2011
    Inventors: David Peretz, Xuemei Wang, Carol Man Gao, Alice Yam, Anthony Lau, Ping Wu
  • Publication number: 20100291598
    Abstract: Assays for detecting PrPSc in a sample are described. In particular, pathogenic prion ELISAs are described. The assays utilize pathogenic prion-specific reagents to capture the PrPSc and digestion with a site-specific protease, for example trypsin or SV-8 protease, to reduce the amount of interference from non-pathogenic prion proteins that are occasionally present in the samples.
    Type: Application
    Filed: April 4, 2008
    Publication date: November 18, 2010
    Inventor: David Peretz
  • Patent number: 7834144
    Abstract: The invention relates to peptoid reagents that interact preferentially with a pathogenic form of a conformational disease protein as compared to a nonpathogenic form of the conformational disease protein where the peptoid reagent comprises an amino-terminal region, a carboxy-terminal region, and at least one peptoid region between the amino-terminal region and the carboxy-terminal region where the peptoid region comprises 3 to about 30 N-substituted glycines, and optionally one or more amino acids. The invention also relates to methods of using the peptoids in detecting and isolating prions, and in the treatment and prevention of prion-related diseases.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: November 16, 2010
    Assignee: Novartis AG
    Inventors: David Peretz, Michael D. Connolly, Ronald Zuckermann, Man Gao, Gulliver Timoteo, Robert M. Shimizu
  • Publication number: 20100196934
    Abstract: The invention relates to an assay method for detecting the presence of PrPSc using at least one sequence-specific protease for a substantially complete digestion of the proteins in a sample, leaving the octarepeat region in both PrPSc and PrPC intact, leaving the protease-resistant core of PrPSc intact and remain connected to the octarepeat region, region, while digesting away at least part of the amino acid sequences in PrPC corresponding to the protease-resistant core in PrPSc. The method further comprises a step of inhibiting further digestion by the protease, a step of denaturation, and a step of detecting the presence of PrPSc using at least two binding partners, a first binding partner and a second binding partner, wherein the first binding partner specifically binds an epitope in the amino-proximal region, and the second binding partner specifically binds an epitope within a region of the protease-resistant core of PrPSc that has been cleaved away in PrPC.
    Type: Application
    Filed: April 3, 2008
    Publication date: August 5, 2010
    Inventors: David Peretz, Alice Yam
  • Publication number: 20100145508
    Abstract: The present invention is an apparatus and method for dispensing collectibles to a user comprising a housing with a user interface, such as displays, speakers, touch screens, push buttons, joy sticks, track balls, mouse(s), spinning dials, wheels, microphone and/or pull actuators. The user interface provides audio visual information related to one or more collectibles. A plurality of hoppers are coupled to a dispensing mechanism and are adapted to hold the collectibles. A controller is coupled to the user interface and the dispensing mechanism. The user may designate one or more collectibles through the user interface. The dispensing mechanism releases the designated collectibles from the appropriate hoppers. The apparatus and method may incorporate one or more games that may be configured to allow a user to affect the collectible being dispensed. Tracking the inventory of available collectibles may also affect the availability of specific collectibles.
    Type: Application
    Filed: September 10, 2009
    Publication date: June 10, 2010
    Inventor: David Peretz
  • Publication number: 20090130774
    Abstract: Peptide reagents that interact preferentially with the PrPsc form of the prion protein are described for use in detecting PrPsc in biological samples. In particular, ELISA assays are described.
    Type: Application
    Filed: January 13, 2006
    Publication date: May 21, 2009
    Inventors: David Peretz, Melissa Michelitsch, Celine Hu, Xuemei Wang, Man Gao, Michael Connolly, Thomas Horn, Ronald Zuckermann, David Chien