Abstract: A pneumatic inhaler that is able to deliver a controlled burst or dose of aerosol from a reservoir of liquid or powder medication. A supersonic jet of gas is emitted from a nozzle and shock waves are developed in the jet. In one embodiment the supersonic jet is directed into a shock chamber. Liquid or micronized powder material is introduced into the supersonic jet to form an aerosol. In one embodiment, smaller aerosol particles are separated from larger aerosol particles with a separator. In another embodiment, the produced aerosol is contained in an aerosol storage chamber prior to inhalation by the users.

Abstract: A pneumatic inhaler that is able to deliver a controlled burst or dose of aerosol from a reservoir of liquid medication. The inhaler is suitable for the aerosolization of liquid medication that is in solution or suspension form. The inhaler is also ideal for the delivery of unique and specialty liquid medications in short aerosol bursts because no additional formulation development is needed and has the further advantage of being able to deliver multiple medications, as mixed by the patient, doctor, or pharmacist, with a single burst at a repeatable output. Because medication and propellant are not mixed until aerosolization occurs, the inhaler is appropriate for more pharmaceutical agents than the current inhalers available and at a substantial cost savings.

Abstract: A pneumatic inhaler that is able to deliver a controlled burst or dose of aerosol from a reservoir of liquid medication. The inhaler is suitable for the aerosolization of liquid medication that is in solution or suspension form. The inhaler is also ideal for the delivery of unique and specialty liquid medications in short aerosol bursts because no additional formulation development is needed and has the further advantage of being able to deliver multiple medications, as mixed by the patient, doctor, or pharmacist, with a single burst at a repeatable output. Because medication and propellant are not mixed until aerosolization occurs, the inhaler is appropriate for more pharmaceutical agents than the current inhalers available and at a substantial cost savings.

Abstract: A pneumatic inhaler that is able to deliver a controlled burst or dose of aerosol from a reservoir of liquid or powder medication. A supersonic jet of gas is emitted from a nozzle and shock waves are developed in the jet. In one embodiment the supersonic jet is directed into a shock chamber. Liquid or micronized powder material is introduced into the supersonic jet to form an aerosol. In one embodiment, smaller aerosol particles are separated from larger aerosol particles with a separator. In another embodiment, the produced aerosol is contained in an aerosol storage chamber prior to inhalation by the users.

Abstract: Polypeptides of HFGAN72 receptor ligands and polynucleotides encoding the polypeptides are provided. Methods of using these polypeptides to diagnose or treat diseases relating to the under- or over-expression of HFGAN72 receptor ligands are also provided. In addition, methods of identifying agonists or antagonists of the interaction of HFGAN72 receptor ligands with the HFGAN72 receptor are provided. Methods of treatment by administering the identified agonists or antagonists to patients in need thereof are further disclosed.

Abstract: Polypeptides of HFGAN72 receptor ligands and polynucleotides encoding the polypeptides are provided. Methods of using these polypeptides to diagnose or treat diseases relating to the under- or over-expression of HFGAN72 receptor ligands are also provided. In addition, methods of identifying agonists or antagonists of the interaction of HFGAN72 receptor ligands with the HFGAN72 receptor are provided. Methods of treatment by administering the identified agonists or antagonists to patients in need thereof are further disclosed.

Abstract: An inhalation therapy device includes a collapsible aerosol storage bag (7) having an opening which connects to the end of a dual port member, one port (8) of which is in fluid communication with a nebulizer. During patient exhalation the aerosol storage bag becomes partially inflated with exhaled gas during the first part of exhalation. The laminar coherent aerosol jet exits the dual port member and remains coherent until reaching the end of the aerosol storage bag, at which time it diverges and expels all exhaled gas from the aerosol storage bag, thus filling the aerosol storage bag with aerosol. All escaping gas exits the aerosol storage bag via the remaining port (9) of the dual port member, where it escapes into the ambient environment through the ambient port. The remaining dual port of the dual port member, in addition to providing means for escaping gas from the aerosol storage bag, is also in fluid communication with the ambient port and the mouthpiece (1).

Abstract: A pneumatic inhaler that is able to deliver a controlled burst or dose of aerosol from a reservoir of liquid medication. The inhaler is suitable for the aerosolization of liquid medication that is in solution or suspension form. The inhaler is also ideal for the delivery of unique and specialty liquid medications in short aerosol bursts because no additional formulation development is needed and has the further advantage of being able to deliver multiple medications, as mixed by the patient, doctor, or pharmacist, with a single burst at a repeatable output. Because medication and propellant are not mixed until aerosolization occurs, the inhaler is appropriate for more pharmaceutical agents than the current inhalers available and at a substantial cost savings.

Abstract: A pneumatic nebulizer that produces a high volume of aerosols for inhalent delivery of medications and other constituencies. High pressure gas formed into a gas jet is passed through a thin choked region of fluid that is entrailed and impinged upon an aerosol amplifier which creates a spray whose aerosol components are directed up through vents to an aerosol outlet for delivery. Larger-sized liquid particles are caused to pool up in a region surrounding the aerosol amplifer and then drip down back into the liquid medication reservoir.

Abstract: A dual area pressure pulmonary modulator apparatus which provides constant flow, pressure cycled ventilatory support to patients. The pressure pulmonary modulator apparatus opens at a selected pressure and shuts at a substantially lower pressure. The pressure pulmonary modulator apparatus can be incorporated into an automatic resuscitator suited for providing ventilatory support during resuscitation and/or transport of patients. The automatic resuscitator may be combined with a nebulizer to serve as a positive pressure aerosol therapy device. The pressure pulmonary modulator apparatus can also be incorporated into a percussive therapy device used for the mobilization of mucus in patients. The pressure pulmonary modulator apparatus may be made almost entirely of injection molded plastic and is inexpensive, portable and disposable.

Abstract: A method and apparatus for storing data defining a graphical outline of an object, the graphical outline comprising a series of curve segments. First, those curve segments which comprise straight line segments are determined. The method next stores a first number of associated control points for each of said curve segments which do not comprise straight line segments. The method then operates to store a reduced number of associated control points for each of the curve segments which comprise straight line segments.