Patents by Inventor David Pleasure

David Pleasure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTRACELLULAR TOLL-LIKE RECEPTORS PATHWAYS AND AXONAL DEGENERATION
    Publication number: 20120207766
    Abstract: The present invention is directed to the identification of novel mechanisms involved in the initiation and spreading of axonal degeneration. In particular, the instant invention relates to the identification of a relationship between Toll-Like Receptors (TLRs) and axonal degeneration and the use of TLR inhibitors as antagonists of axonal degeneration.
    Type: Application
    Filed: January 30, 2012
    Publication date: August 16, 2012
    Inventors: Athena Soulika, David Pleasure
  • Human leucine-zipper protein kinase and methods of use
    Patent number: 5676945
    Abstract: A novel protein kinase, leucine-zipper protein kinase, 668 amino acids in length is provided by the present invention. This protein kinase is localized to the human brain. Nucleic acid sequences encoding the protein kinase are also provided.
    Type: Grant
    Filed: February 28, 1995
    Date of Patent: October 14, 1997
    Assignee: Children's Hospital of Philadelphia
    Inventors: Usharani Reddy, David Pleasure
  • Nucleic acid sequences encoding human leucine-zipper protein-kinase
    Patent number: 5554523
    Abstract: A novel protein kinase, leucine-zipper protein kinase, 668 amino acids in length is provided by the present invention. This protein kinase is localized to the human brain. Nucleic acid sequences encoding the protein kinase are also provided.
    Type: Grant
    Filed: March 1, 1994
    Date of Patent: September 10, 1996
    Assignee: Children's Hospital of Philadelphia
    Inventors: Usharani Reddy, David Pleasure
  • Methods for screening for neurotoxicity using a clonal human teratocarcinoma cell line
    Patent number: 5449609
    Abstract: Methods for screening for excitotoxic effects of an agent on neurons of the central nervous system are provided by the present invention.
    Type: Grant
    Filed: January 31, 1994
    Date of Patent: September 12, 1995
    Assignee: Children's Hospital of Philadelphia
    Inventors: Donald P. Younkin, David Pleasure