Patents by Inventor David Polsky

David Polsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for detecting circulating mutant BRAF DNA
    Patent number: 7442507
    Abstract: The present invention relates to a method for detecting the presence of circulating mutant BRAF DNA, which may be present in circulating melanoma cells or as DNA shed from tumor cells. Methods, compositions and kits which employ one or more sets of BRAF mutant specific primer pairs for detection of circulating mutant BRAF DNA are presented. Also provided are methods for diagnosing and/or determining stage/progression of a melanoma in a mammal based on detection of a BRAF mutant nucleic acid sequence. Such methods are also well suited to monitoring disease activity in patients with active disease or those in remission.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: October 28, 2008
    Assignees: New York University School of Medicine, Memorial Sloan-Kettering Cancer Center
    Inventors: David Polsky, Iman Osman, Paul B. Chapman
  • Methods for detecting circulating mutant BRAF DNA
    Publication number: 20060246476
    Abstract: The present invention relates to a method for detecting the presence of circulating mutant BRAF DNA, which may be present in circulating melanoma cells or as DNA shed from tumor cells. Methods, compositions and kits which employ one or more sets of BRAF mutant specific primer pairs for detection of circulating mutant BRAF DNA are presented. Also provided are methods for diagnosing and/or determining stage/progression of a melanoma in a mammal based on detection of a BRAF mutant nucleic acid sequence. Such methods are also well suited to monitoring disease activity in patients with active disease or those in remission.
    Type: Application
    Filed: January 24, 2006
    Publication date: November 2, 2006
    Inventors: David Polsky, Iman Osman, Paul Chapman