Patents by Inventor David R. Barnidge

David R. Barnidge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS
    Publication number: 20240410899
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Application
    Filed: August 29, 2024
    Publication date: December 12, 2024
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills
  • Identification and monitoring of immunoglobulin J chains
    Patent number: 12153052
    Abstract: This document relates to materials and methods for identifying and monitoring immunoglobulin J chains in a sample, such as a biological sample, using mass spectrometry techniques.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: November 26, 2024
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge
  • Isotyping immunoglobulins using accurate molecular mass
    Patent number: 12099065
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Grant
    Filed: February 7, 2023
    Date of Patent: September 24, 2024
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills
  • Identification and monitoring of apoptosis inhibitor of macrophage
    Patent number: 11946937
    Abstract: This document provides materials and methods for identifying and quantifying AIM polypeptides in a sample using mass spectrometry techniques. For example, methods of using mass spectrometry to identify and quantify AIM polypeptides in a serum sample are provided. In some cases, quantification of AIM polypeptides can be used to diagnose and/or treat patients having a disease or disorder characterized by altered (e.g., increased or decreased) AIM polypeptide levels.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: April 2, 2024
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge
  • ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS
    Publication number: 20230243845
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Application
    Filed: February 7, 2023
    Publication date: August 3, 2023
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills
  • Isotyping immunoglobulins using accurate molecular mass
    Patent number: 11604196
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: March 14, 2023
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills
  • Identification of immunoglobulin free light chains by mass spectrometry
    Patent number: 11209439
    Abstract: This document relates to methods for identifying one or more immunoglobulin free light chains in a sample using mass spectrometry. For example, this document relates to a method for identifying one or more immunoglobulin free light chains in a sample that includes (a) providing a sample; (b) subjecting the sample to a mass spectrometry technique to obtain a mass spectrum of the sample; and (c) identifying the presence of the one or more immunoglobulin free light chains.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: December 28, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David R. Barnidge, David L. Murray
  • Identification and monitoring of cleaved immunoglobulins by molecular mass
    Patent number: 10955420
    Abstract: This document relates to materials and methods for identifying and monitoring immunoglobulin cleavage (e.g., IgG cleavage) in a sample, such as a biological sample, using mass spectrometry techniques.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: March 23, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David R. Barnidge, David L. Murray
  • ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS
    Publication number: 20200341003
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Application
    Filed: July 16, 2020
    Publication date: October 29, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills
  • IDENTIFICATION AND MONITORING OF APOPTOSIS INHIBITOR OF MACROPHAGE
    Publication number: 20200292556
    Abstract: This document provides materials and methods for identifying and quantifying AIM polypeptides in a sample using mass spectrometry techniques. For example, methods of using mass spectrometry to identify and quantify AIM polypeptides in a serum sample are provided. In some cases, quantification of AIM polypeptides can be used to diagnose and/or treat patients having a disease or disorder characterized by altered (e.g., increased or decreased) AIM polypeptide levels.
    Type: Application
    Filed: September 13, 2018
    Publication date: September 17, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge
  • IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN J CHAINS
    Publication number: 20200284800
    Abstract: This document relates to materials and methods for identifying and monitoring immunoglobulin J chains in a sample, such as a biological sample, using mass spectrometry techniques.
    Type: Application
    Filed: September 13, 2018
    Publication date: September 10, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge
  • IDENTIFICATION AND MONITORING OF ACID HYDROLYSIS PRODUCTS OF IMMUNOGLOBULIN HEAVY CHAINS
    Publication number: 20200271663
    Abstract: This document provides materials and methods for identifying and/or quantifying immunoglobulin heavy chains (e.g., IgG heavy chains) in a sample, such as a biological sample, using mass spectrometry techniques. For example, mass spectrometry techniques that can be used to identify and/or quantify IgG heavy chain acid hydrolysis products in a serum sample without the need for any IgG cleavage reagents (e.g., enzymes) are provided.
    Type: Application
    Filed: September 13, 2018
    Publication date: August 27, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge
  • Isotyping immunoglobulins using accurate molecular mass
    Patent number: 10753945
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: August 25, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills
  • Quantifying monoclonal antibody therapeutics by LC-MS/MS
    Patent number: 10690676
    Abstract: This document relates to methods for quantifying antibody therapeutics using mass spectrometry techniques.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: June 23, 2020
    Assignee: Mayo Roundation for Medical Education and Research
    Inventors: David R. Barnidge, Maria Alice Vieira Willrich, David L. Murray, Melissa R. Snyder
  • ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS
    Publication number: 20200003784
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Application
    Filed: March 8, 2019
    Publication date: January 2, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills
  • IDENTIFICATION AND MONITORING OF CLEAVED IMMUNOGLOBULINS BY MOLECULAR MASS
    Publication number: 20190195888
    Abstract: This document relates to materials and methods for identifying and monitoring immunoglobulin cleavage (e.g., IgG cleavage) in a sample, such as a biological sample, using mass spectrometry techniques.
    Type: Application
    Filed: September 7, 2017
    Publication date: June 27, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David R. Barnidge, David L. Murray
  • Isotyping immunoglobulins using accurate molecular mass
    Patent number: 10267806
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: April 23, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills
  • IDENTIFICATION OF IMMUNOGLOBULIN FREE LIGHT CHAINS BY MASS SPECTROMETRY
    Publication number: 20180267057
    Abstract: This document relates to methods for identifying one or more immunoglobulin free light chains in a sample using mass spectrometry. For example, this document relates to a method for identifying one or more immunoglobulin free light chains in a sample that includes (a) providing a sample; (b) subjecting the sample to a mass spectrometry technique to obtain a mass spectrum of the sample; and (c) identifying the presence of the one or more immunoglobulin free light chains.
    Type: Application
    Filed: September 26, 2016
    Publication date: September 20, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David R. Barnidge, David L. Murray
  • QUANTIFYING MONOCLONAL ANTIBODY THERAPEUTICS BY LC-MS/MS
    Publication number: 20180106815
    Abstract: This document relates to methods for quantifying antibody therapeutics using mass spectrometry techniques.
    Type: Application
    Filed: July 29, 2015
    Publication date: April 19, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David R. Barnidge, Maria Alice Vieira Willrich, David L. Murray, Melissa R. Snyder
  • ISOTYPING IMMUNOGLOBULINS USING ACCURATE MOLECULAR MASS
    Publication number: 20170023584
    Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.
    Type: Application
    Filed: April 3, 2015
    Publication date: January 26, 2017
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: David L. Murray, David R. Barnidge, Surendra Dasari, John R. Mills