Patents by Inventor David R. Cheng

David R. Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRISPR-associated transposon systems and components
    Patent number: 12054754
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of DNA, RNA, and protein substrates. Each system includes one or more protein components and one or more nucleic acid components that together target DNA, RNA, or protein substrates.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: August 6, 2024
    Assignee: Arbor Biotechnologies, Inc.
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan
  • CRISPR DNA targeting enzymes and systems
    Patent number: 11976308
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Grant
    Filed: December 28, 2022
    Date of Patent: May 7, 2024
    Assignee: ARBOR BIOTECHNOLOGIES, INC.
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan, Tia M. Ditommaso
  • CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20240101990
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: September 12, 2023
    Publication date: March 28, 2024
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan, Tia M. DiTommaso
  • COMPOSITIONS COMPRISING A NUCLEASE AND USES THEREOF
    Publication number: 20240093228
    Abstract: The present invention relates to nucleases or nucleic acids encoding the nucleases, RNA guides or nucleic acids encoding the RNA guides, processes for characterizing the nucleases and/or RNA guides, compositions comprising the nucleases and/or RNA guides, and kits and/or methods for preparing and/or using the nucleases and/or RNA guides.
    Type: Application
    Filed: January 21, 2022
    Publication date: March 21, 2024
    Inventors: David A. SCOTT, David R. CHENG, Winston X. YAN, Tia M. DITOMMASO
  • CRISPR DNA targeting enzymes and systems
    Patent number: 11912992
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Grant
    Filed: December 9, 2022
    Date of Patent: February 27, 2024
    Assignee: ARBOR BIOTECHNOLOGIES, INC.
    Inventors: Shaorong Chong, Winston X Yan, David A. Scott, David R. Cheng, Pratyusha Hunnewell
  • COMPOSITIONS COMPRISING A NUCLEASE AND USES THEREOF
    Publication number: 20240011031
    Abstract: The present invention relates nucleases, processes for characterizing the nucleases, compositions comprising the nucleases, and methods of using the nucleases.
    Type: Application
    Filed: August 17, 2021
    Publication date: January 11, 2024
    Applicant: Arbor Biotechnologies, Inc.
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan, Tia M. Ditommaso
  • NOVEL CRISPR-ASSOCIATED SYSTEMS AND COMPONENTS
    Publication number: 20230407281
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered Type III-E CRISPR-Cas systems, components, and methods for targeted modification of DNA, RNA, and protein substrates. Each system includes one or more protein components and one or more nucleic acid components that together target DNA, RNA, or protein substrates.
    Type: Application
    Filed: April 24, 2023
    Publication date: December 21, 2023
    Inventors: David R. Cheng, David A. Scott, Winston X. Yan
  • CRISPR DNA targeting enzymes and systems
    Patent number: 11795442
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Grant
    Filed: August 17, 2022
    Date of Patent: October 24, 2023
    Assignee: ARBOR BIOTECHNOLOGIES, INC.
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan, Tia M. DiTommaso
  • NOVEL CRISPR DNA AND RNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20230242891
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: March 14, 2019
    Publication date: August 3, 2023
    Inventors: Elise Keston-Smith, David A. Scott, David R. Cheng, Winston X. Yan, Pratyusha Hunnewell, Jason Carte
  • NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20230212542
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: December 28, 2022
    Publication date: July 6, 2023
    Inventors: David A. SCOTT, David R. CHENG, Winston X. YAN, Tia M. DITOMMASO
  • NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20230183688
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: December 9, 2022
    Publication date: June 15, 2023
    Inventors: Shaorong Chong, Winston X. Yan, David A. Scott, David R. Cheng, Pratyusha Hunnewell
  • CRISPR-associated systems and components
    Patent number: 11667904
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered Type III-E CRISPR-Cas systems, components, and methods for targeted modification of DNA, RNA, and protein substrates. Each system includes one or more protein components and one or more nucleic acid components that together target DNA, RNA, or protein substrates.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: June 6, 2023
    Assignee: ARBOR BIOTECHNOLOGIES, INC.
    Inventors: David R. Cheng, David A. Scott, Winston X. Yan
  • Crispr DNA targeting enzymes and systems
    Patent number: 11643654
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR-Cas systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: May 9, 2023
    Assignee: ARBOR BIOTECHNOLOGIES, INC.
    Inventors: David R. Cheng, David A. Scott, Winston X. Yan
  • NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20230057102
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: August 17, 2022
    Publication date: February 23, 2023
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan, Tia M. DiTommaso
  • COMPOSITIONS COMPRISING A NUCLEASE AND USES THEREOF
    Publication number: 20230045187
    Abstract: The present invention relates to genes coding for nucleases, processes for characterizing the nucleases, cells comprising the nucleases, and methods of using the nucleases.
    Type: Application
    Filed: December 3, 2020
    Publication date: February 9, 2023
    Inventors: David A. Scott, Winston X. Yan, David R. Cheng, Tia M. DiTommaso
  • NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20230016656
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: August 26, 2020
    Publication date: January 19, 2023
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan, Tia M. Ditommaso
  • NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20220372456
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: July 10, 2020
    Publication date: November 24, 2022
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan, Tia Marie Ditommaso
  • NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20220333102
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR-Cas systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: June 1, 2022
    Publication date: October 20, 2022
    Inventors: David R. Cheng, David A. Scott, Winston X. Yan
  • NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
    Publication number: 20220315913
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids such as DNA. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Application
    Filed: June 12, 2020
    Publication date: October 6, 2022
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan
  • CRISPR DNA targeting enzymes and systems
    Patent number: 11453867
    Abstract: The disclosure describes novel systems, methods, and compositions for the manipulation of nucleic acids in a targeted fashion. The disclosure describes non-naturally occurring, engineered CRISPR systems, components, and methods for targeted modification of nucleic acids. Each system includes one or more protein components and one or more nucleic acid components that together target nucleic acids.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: September 27, 2022
    Assignee: ARBOR BIOTECHNOLOGIES, Inc.
    Inventors: David A. Scott, David R. Cheng, Winston X. Yan, Tia M. DiTommaso